Phenylpropanoids and polyketides
Cayman Chemical EpIcatechIn 25mg
A polyphenol flavonoid with diverse biological activities; scavenges DPPH radicals in a cell-free assay at 5 µM; inhibits COX-1 (IC50 = 3.2 μM); acts synergistically with epigallocatechin gallate to induce apoptosis in, and reduce the proliferation of, PC-9 cells at 200 µM; reduces LPS-induced increases in plasma creatinine and urea levels in a rat model of renal inflammation at 80 mg/kg
Medchemexpress LLC (-)-Epicatechin gallate (standard) | 1257-08-5 | 442.37 | 1 MG
(-)-Epicatechin gallate (Standard) is the analytical standard of (-)-Epicatechin gallate. This product is intended for research and analytical applications. It inhibits cyclooxygenase-1 (COX-1) with an IC50 of 7.5 μM, and is a GLUT1 and GLUT5 inhibitor, decreasing cell growth of GLUT5-expressing hxt 0 yeast cells.
- Targets: COX, autophagy, virus protease, GLUT
- Research areas: Infection, cancer
- Structural classification: Flavonoids, flavanols, phenols, polyphenols
- Source classification: *Camellia sinensis* (L.) O. Ktze. plants, Theaceae
Cayman Chemical LuteolIn 7-O-GlucuronIde 1mg
A flavonoid with antioxidant, enzyme inhibitory, and anti-inflammatory properties; scavenges DPPH radicals in a cell-free assay (IC50 = 80.6 μM); inhibits porcine α-amylase and yeast α-glucosidase in vitro (IC50s = 61.5 and 14.7 μM, respectively); inhibits rat aldose reductase in vitro (IC50 = 0.7 μM) and sorbitol accumulation in isolated rat lens at 5 μg/ml; inhibits LPS-induced cytokine release from RAW 264.7 macrophages in a dose-dependent manner
TARGETMOL CHEMICALS INC Luteolin 7-diglucuronide 5MG
Also available in 1 mg, 10 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. Luteolin 7-diglucuronide, the major flavonoid isolated from Verbena officinalis and Aloysia triphylla. Purity 98.44%
TARGETMOL CHEMICALS INC Epicatechin 100MG
Also available in 1 mL, 10 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. (-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1beta-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-kB. Purity 98%
Indofine Chemical Epicatechin With Hplc, 10 Mg
EPICATECHIN with HPLC 10 MG, Herbal Standards, 3,5,7,3',4'-Pentahydroxyflavan, C15H14O6, MW: 290.28, 99% by HPLC, 490-46-0, MFCD00075648
Cayman Chemical ApIgenIn 7-glucosIde 50mg
A flavonoid with anti-inflammatory and anxiolytic activities; inhibits LPS-induced nitric oxide production in RAW 264.7 cells from 0.16-10 μM; reduces pulmonary edema and lung inflammation in a mouse model of LPS-induced acute lung injury at 10 mg/kg; increases the number of entries and the time spent in the open arms of the elevated plus maze in rats
Selleck Chemical LLC Luteolin S2320-1g
Luteolin (Luteoline Luteolol Digitoflavone) is a flavonoid found in Terminalia chebula which is a non-selective phisphodiesterase PDE inhibitor for PDE1-5 with Ki of 15 0 M 6 4 M 13 9 M 11 1 M and 9 5 M respectively
Medchemexpress LLC (-)-epicatechin | 490-46-0 | MFCD00075648 | ≥97.0% | 290.27 | C15H14O6 | 10 MG
(-)-Epicatechin is a naturally occurring flavanol (catechin) used as a research reagent and analytical standard. It is used in biochemical and cellular assays to study cyclooxygenase activity and inflammatory signaling pathways.
Medchemexpress LLC Luteolin 5-O-glucoside | 20344-46-1 | 448.38 | 1 MG
Luteolin 5-O-glucoside is a major flavonoid extracted from *Cirsium maackii*. It exhibits anti-inflammatory properties by inhibiting LPS-induced NO production and t-BHP-induced ROS generation. This compound also suppresses the expression of iNOS and COX-2 in macrophages, making it suitable for various research applications focusing on inflammation pathways.
- Inhibits LPS-induced NO production.
- Suppresses t-BHP-induced ROS generation.
- Reduces expression of iNOS and COX-2 in macrophages.
- Derived from natural plant sources.
Selleck Chemical LLC Apigenin S2262-1g
Apigenin is a potent P450 inhibitor for CYP2C9 with Ki of 2 M
Medchemexpress LLC Apigenin-7-O-sulfate potassium | 120562-19-8 | 99.9% | 388.39 g·mol⁻1 | C15H9KO8S | 5mg
Apigenin-7-O-sulfate is a major flavonoid which is found to be a distinctive feature of plants from the Bay of Cadiz and can be extracted from these plants[1]
Medchemexpress LLC Apigenin (standard) | 520-36-5 | 270.24 | 50 MG
Apigenin (Standard) is an analytical standard intended for research and analytical applications. It is a competitive CYP2C9 inhibitor with a Ki of 2 μM and serves as a reference standard for assays.
- Analytical standard for research and analytical applications
- Competitive CYP2C9 inhibitor
- Reference standard for assays
- Used in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS applications
Cayman Chemical Luteolin Inhibitors
A common dietary phenolic flavone; inhibits soybean and reticulocyte 15-lipoxygenases (IC50 = 0.6 µM); inhibits the release of TNFα from neutrophils; inhibits matrix metalloproteinases