Perphenazine-d4 is the deuterium labeled Perphenazine, a typical antipsychotic agent that inhibits several receptors, including the 5-HT2A receptor, Alpha-1A adrenergic receptor, Dopamine receptor D2/D3, D2L receptor, and Histamine H1 receptor. Deuterium substitution in drug molecules, as seen in Perphenazine-d4, has garnered attention due to its potential to influence the pharmacokinetic and metabolic profiles of drugs. The product is a solid, ranging in color from white to off-white, with a molecular weight of 407.99. It dissolves in DMSO at 100 mg/mL, though ultrasonic treatment may be required.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.