Diterpenoids
Medchemexpress LLC Nab-Paclitaxel 50mg | 50mg
Nab-Paclitaxel (Nanoparticle albumin-bound Paclitaxel) is an albumin-bound nanoparticle formulation of Paclitaxel (HY-B0015) Nab-Paclitaxel is composed of albumin and the active pharmaceutical ingredient Paclitaxel in which human albumin is used as an excipient to disperse and stabilize particles and carry the main drug Nab-Paclitaxel is a solvent-free taxane with higher response rates and improved tolerability Nab-Paclitaxel displays less toxicity and greater antitumor activity Nab-Paclitaxel is more readily available for tumor cell uptake in three rhabdomyosarcoma seven neuroblastoma cell lines and one ostersarcoma cell line Nab-Paclitaxel can be studied in cancer research for example breast cancer and solid tumors (The product specifications below only indicate the effective content of Paditaxel the actual albumin quality depends on the batch the ratio of each ingredient in this product is Paditaxel albumin -1 7 1 11)[1][2]
Medchemexpress LLC Nab-Paclitaxel 5mg | 5mg
Nab-Paclitaxel (Nanoparticle albumin-bound Paclitaxel) is an albumin-bound nanoparticle formulation of Paclitaxel (HY-B0015) Nab-Paclitaxel is composed of albumin and the active pharmaceutical ingredient Paclitaxel in which human albumin is used as an excipient to disperse and stabilize particles and carry the main drug Nab-Paclitaxel is a solvent-free taxane with higher response rates and improved tolerability Nab-Paclitaxel displays less toxicity and greater antitumor activity Nab-Paclitaxel is more readily available for tumor cell uptake in three rhabdomyosarcoma seven neuroblastoma cell lines and one ostersarcoma cell line Nab-Paclitaxel can be studied in cancer research for example breast cancer and solid tumors (The product specifications below only indicate the effective content of Paditaxel the actual albumin quality depends on the batch the ratio of each ingredient in this product is Paditaxel albumin -1 7 1 11)[1][2]
Medchemexpress LLC Paclitaxel | 33069-62-4 | MFCD00869953 | 100.0% | 853.91 g·mol⁻¹ | C47H51NO14 | 10 MG
Paclitaxel is a microtubule-stabilizing antineoplastic reagent used in biological research to inhibit mitosis and induce apoptosis. It is supplied as a solid for preparation of experimental stock solutions and is commonly used in cell culture, in vivo studies, and assay development.
- Stabilizes tubulin polymerization and induces mitotic arrest.
- Used for cell culture, in vivo tumor models, and assay development.
- Supplied as a solid powder suitable for dissolution in DMSO or other organic solvents.
- Storage recommendations: protect from light; solids at 4°C; solutions at -20°C (short term) or -80°C (long term).
- Analytical identity confirmed by LC-MS; batch-specific purity reported by certificate of analysis.
Enzo Life Sciences Tanshinone IIA (25mg). CAS: 568-72-9
Tanshinone IIA is a diterpenoid naphthoquinone found in the traditional Chinese medicine Tanshen (Salvia sp). It inhibits AP-1 activity by suppressing jun-fos-DNA complex formation (IC50=0.22 µM) and induces apoptosis in a variety of cell lines Purity: ≥93% (HPLC). Solubility: Soluble in DMSO (25mg/ml) or 100% ethanol (5mg/ml). Long Term Storage: +4°C.
Apexbio Technology LLC Docetaxel 114977-28-5 100mg
Docetaxel (CAS 114977-28-5) is a semisynthetic taxane derivative originally isolated from the European yew (Taxus baccata) As an antineoplastic agent docetaxel disrupts microtubule dynamics by stabilizing tubulin polymerization resulting in cell cycle arrest at mitosis and subsequent apoptosis In both in vitro and in vivo studies docetaxel demonstrates pronounced cytotoxic activity against diverse tumor types such as breast lung ovarian head and neck and gastric cancers Research particularly highlights its enhanced potency against ovarian cancer cell lines compared to paclitaxel cisplatin and etoposide indicating substantial research value in oncology programs
AdipoGen Paclitaxel
Chemical. CAS 33069-62-4. Formula C47H51NO14. MW 853.9. Isolated from the bark of the pacific yew tree Taxus brevifolia. Anticancer compound. Chemotherapeutic used in patients with cancer and advanced forms of Kaposis sarcoma. Microtubule assembly stabilizer. Reversibly binds to polymerized tubulin. Anti-mitotic. Mitotic spindle assembly, chromosome segregation and cell division inhibitor. Induces cell cycle arrest at the G2/M phase. Apoptosis inducer through aberrant activation of cyclin-dependent kinases CKDs and the c-Jun N-terminal kinase/stress activated protein kinase JNK/SAPK. Immunosuppressor. Immunostimulant. Antiproliferative agent for the prevention of restenosis. TRAIL sensitizer
Sigma Aldrich Fine Chemicals Biosciences Aphidicolin - CAS 38966-21-1 - Calbiochem Aphidicolin, CAS 38966-21-1, is a cell-permeable antibiotic that acts as a cell synchronization agent. Blocks the cell cycle at early S-phase. | 38966-21-1 | MFCD00083214 | 1MG
Aphidicolin - CAS 38966-21-1 - Calbiochem Aphidicolin, CAS 38966-21-1, is a cell-permeable antibiotic that acts as a cell synchronization agent. Blocks the cell cycle at early S-phase. | Purity: >=98% (TLC) | Mol Wt: 338.48 | 38966-21-1 | MFCD00083214 | 1MG
Sigma Aldrich Fine Chemicals Biosciences Aphidicolin from Nigrospor5MG
Aphidicolin from Nigrospor5MG
Sigma Aldrich Fine Chemicals Biosciences Geranylgeranylacetone | 6809-52-5 | MFCD00869547 | 10MG
Geranylgeranylacetone | Purity: >=98% (HPLC) | Mol Wt: 330.55 | 6809-52-5 | MFCD00869547 | 10MG
Sigma Aldrich Fine Chemicals Biosciences Cryptotanshinone >=98% (HPLC) | 35825-57-1 | MFCD07636810 | 5MG
Cryptotanshinone >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 296.36 | 35825-57-1 | MFCD07636810 | 5MG
Abcam Paclita x el, Anticancer agent, 50MG
MW 853.9 Da, Purity >98%. Anticancer agent. Inhibits depolymerization of microtubules, causing mitotic arrest in cancer cells, and apoptosis.
The product is subject to the following: Abcam Restricted Use Statement
Sigma Aldrich Fine Chemicals Biosciences Anhydrous Docetaxel European Pharmacopoeia (EP) Reference Standard | 114977-28-5 | MFCD00800737 |
Anhydrous Docetaxel European Pharmacopoeia (EP) Reference Standard | Mol Wt: 807.88 | 114977-28-5 | MFCD00800737 |
Sigma Aldrich Fine Chemicals Biosciences Tanshinone IIA >=97% (HPLC) | 568-72-9 | MFCD00238692 | 25MG
Tanshinone IIA >=97% (HPLC) | Purity: >=97% (HPLC) | Mol Wt: 294.34 | 568-72-9 | MFCD00238692 | 25MG
Selleck Chemical LLC Paclitaxel S1150-100mg
Paclitaxel is a microtubule polymer stabilizer with IC50 of 0 1 pM in human endothelial cells Paclitaxel can cause both mitotic arrest and apoptotic cell death Paclitaxel also induces autophagy
Cayman Chemical Paclitaxel Neurochemicals
A potent disruptor of microtubules used as a chemotherapeutic compound; inhibits growth of cervical (HeLa), lung (A549), breast (MCF-7), colon (HT-29), ovarian (OVG-1), and pancreatic (PC-Sh) carcinomas with IC50 values ranging from 2.5-7.5 nM; induces mitotic arrest and initiates apoptosis of cancer cells through multiple mechanisms