Diterpenoids
eMolecules Tanshinone IIA | 568-72-9 | MFCD00238692 | 100mg
Ambeed | Tanshinone IIA | 100mg | 552521161 | A104838 | | 568-72-9 | MFCD00238692 | 294.350 | C19H18O3
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Medchemexpress LLC 4,4'-sulfonylbis(2-methylphenol) | 16346-97-7 | MFCD00130281 | 97.0% | 278.32 g·mol-1 | C14H14O4S | 25 MG
Topoisomerase IIα-IN-9 is a bisphenol-derived small-molecule inhibitor of human DNA topoisomerase IIα intended for research use. Reported biochemical activity includes Topo II inhibition (IC50 ≈ 571 μM) and cell growth inhibitory activity in K562 and CHO cells (IC50 ≈ 117 μM and 218 μM, respectively). Molecular formula C14H14O4S and molecular weight 278.32 g·mol-1 are provided; consult the Certificate of Analysis for purity and storage conditions.
- Moderate inhibitor of DNA topoisomerase IIα.
- Exhibits cell growth inhibition in selected cell lines.
- Provided as a characterized small molecule with formula and molecular weight.
- Suitable for biochemical assays and cell-based research applications.
- Certificate of Analysis available for purity and handling details.
Medchemexpress LLC 4,4'-sulfonylbis(2-methylphenol) | 16346-97-7 | MFCD00130281 | 278.32 g/mol | C14H14O4S | 10 MG
Topoisomerase IIα-IN-9 (4,4'-sulfonylbis(2-methylphenol)) is a bisphenol compound that moderately inhibits human DNA topoisomerase II and reduces cell proliferation in selected cell lines. It is supplied for laboratory research; lot-specific purity, solubility, and storage conditions are provided in the product data sheet and Certificate of Analysis.
- Moderate topoisomerase II inhibition (IC50: 571 μM).
- Inhibits K562 cell growth (IC50: 117 μM) and CHO cell growth (IC50: 218 μM).
- Molecular weight 278.32 g/mol and formula C14H14O4S.
- CAS number 16346-97-7 for unambiguous identification.
- Intended for research use; consult Certificate of Analysis for purity and storage.
eMolecules Tanshinone i | 568-73-0 | MFCD00210563 | 1g
Combi-Blocks, Inc. | Tanshinone i | 1g | 603145422 | QC-9410 | 95.000 | 568-73-0 | MFCD00210563 | 276.291 | C18H12O3
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Abcam LDN-57444, UCH-L1 inhibitor, 25MG
MW 397.6 Da, Purity >98%. Reversible, competitive ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor (Ki = 0.4 μM. Increases ubiquitinated protein levels and decreases proteasome activity. Also induces apoptosis.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Myricetin, irreversible Tr x R inhibitor, 5MG
MW 318.24 g/mol, Purity >97%. Directly inhibits MEK, JAK1, Akt and MKK4 kinase activity. Able to inhibit cytochrome P450 3A4 and 2C9 (IC₅₀ = 7.81 and 13.5 μM, respectively). .
The product is subject to the following: Abcam Restricted Use Statement
Abcam Paclita x el, Anticancer agent, 10MG
MW 853.9 Da, Purity >98%. Anticancer agent. Inhibits depolymerization of microtubules, causing mitotic arrest in cancer cells, and apoptosis.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical Paclitaxel, 33069-62-4, 100 mg
Molecular Formula C47H51NO14, Purity ≥98%, Formula Weight 853.9, Synonyms: NSC 125973; A potent disruptor of microtubules used as a chemotherapeutic compound; inhibits growth of cervical (HeLa), lung (A549), breast (MCF-7), colon (HT-29), ovarian (OVG-1), and pancreatic (PC-Sh) carcinomas with IC50 values ranging from 2.5-7.5 nM; induces mitotic arrest and initiates apoptosis of cancer cells through multiple mechanisms.