Diterpenoids
Medchemexpress LLC Isophytol (isovegetable alcohol) | 505-32-8 | MFCD00048380 | 99.7% | 296.53 | C20H40O | 100 G
Isophytol (isovegetable alcohol) is a branched-chain diterpenoid alcohol provided for research use as a biochemical assay reagent. It is a clear, oily organic compound (C20H40O, MW 296.53) commonly used in biochemical and analytical applications; manufacturer-stated purity is approximately 99.7%.
- Biochemical assay reagent for life-science research.
- High nominal purity suitable for analytical applications.
- Clear, oily liquid form for easy formulation and handling.
- Supplied in multiple pack sizes for laboratory convenience.
Medchemexpress LLC Cucurbitacin IIa | 58546-34-2 | 562.73 | 1 ML
Cucurbitacin IIa, also known as Hemslecin A, is an orally active and blood-brain barrier-permeable EGFR inhibitor, demonstrating an IC50 of 1.455 nM against human EGFR. It plays a role in inducing caspase-3-dependent apoptosis, downregulating survivin expression, and enhancing autophagy levels. This compound disrupts the actin cytoskeleton through actin aggregation, arrests the cell cycle at the G2/M phase, and provides anti-inflammatory effects by inhibiting the EGFR-MAPK signaling pathway.
- Orally active, blood-brain barrier-permeable EGFR inhibitor
- Induces caspase-3-dependent apoptosis
- Downregulates survivin expression
- Enhances autophagy levels
- Disrupts actin cytoskeleton via actin aggregation
- Arrests cell cycle at G2/M phase
- Exerts anti-inflammatory activity by inhibiting EGFR-MAPK signaling pathway
- Suitable for research in inflammation-related diseases, depression, and cancers
Medchemexpress LLC Tanshinone IIA sulfonate sodium | 69659-80-9 | MFCD09028094 | 396.39 | 50 MG
Tanshinone IIA sulfonate (sodium) is a derivative of tanshinone IIA, acting as an inhibitor of store-operated Ca2+ entry (SOCE), and is utilized in the treatment of cardiovascular disorders. It is intended for research use only and is not sold to patients.
- Acts as an inhibitor of store-operated Ca2+ entry (SOCE).
- Used to treat cardiovascular disorders.
- Inhibits hypoxia-induced PKG and PPAR-γ downregulation.
- Suppresses TRPC1 and TRPC6 expression and reverses suppressive effects on basal calcium concentration and SOCE in hypoxic PASMCs.
- Inhibits CYP3A4 activity.
- Attenuates scopolamine-induced cognitive dysfunctions and improves the cholinergic system.
- Increases superoxide dismutase activity and decreases oxidative stress markers.
- Alleviates hypoxia-induced changes in chronic hypoxia PH rat model.
- Prevents peritoneal adhesion.
Selleck Chemical LLC Cryptotanshinone (Tanshinone C) S2285-10mM/1mL
Cryptotanshinone (Tanshinone C) is a STAT3 inhibitor with IC50 of 4 6 M in a cell-free assay strongly inhibits phosphorylation of STAT3 Tyr705 with a small effect on STAT3 Ser727 but none against STAT1 nor STAT5 Cryptotanshinone induces ROS-dependent autophagy and mitochondria-mediated apoptosis
Medchemexpress LLC HY-N0360 10mg Medchemexpress, Dihydrotanshinone I CAS:87205-99-0 Purity:>98%
Medchemexpress, HY-N0360 10mg Dihydrotanshinone I CAS:87205-99-0 Dihydrotanshinone I is a natural compound extracted from Salvia miltiorrhiza Bunge which has been widely used for treating cardiovascular diseases. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-N0134 5mg Medchemexpress, Tanshinone I CAS:568-73-0 Purity:>98%
Medchemexpress, HY-N0134 5mg Tanshinone I CAS:568-73-0 Tanshinone I is an inhibitor of type IIA human recombinant sPLA 2 ( IC 50 =11 μM) and rabbit recombinant cPLA 2 ( IC 50 =82 μM). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 568-72-9 | Tanshinone IIA | MFCD00238692 | 100mg
Ambeed | Tanshinone IIA | 100mg | 552521161 | A104838 | 568-72-9 | MFCD00238692 | 294.350 | C19H18O3
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Medchemexpress LLC Cucurbitacin IIa | 58546-34-2 | 562.73 | 1 MG
Cucurbitacin IIa, also known as Hemslecin A, is an orally active EGFR inhibitor capable of permeating the blood-brain barrier. It demonstrates an IC50 of 1.455 nM against human EGFR and exhibits anti-inflammatory activity by inhibiting the EGFR-MAPK signaling pathway.
Features and Benefits:
- Induces caspase-3-dependent apoptosis.
- Downregulates survivin expression.
- Enhances autophagy levels.
- Disrupts the actin cytoskeleton via actin aggregation.
- Arrests the cell cycle at the G2/M phase.
- Supports research into inflammation-related diseases.
- Useful in studies on depression and cancers like non-small cell lung cancer.
Selleck Chemical LLC Tanshinone IIA 50mg 568-72-9 Tanshinone B
Tanshinone IIA (Tanshinone B) is the most abundant diterpene quinone in Danshen, Salviae miltiorrhizae Radix, a widely prescribed traditional herbal medicine that is used to treat cardiovascular and inflammatory diseases; A natural monoacylglycerol lipase inhibitor. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Apexbio Technology LLC Tanshinone IIA 568-72-9 10mM (in 1mL DMSO)
Tanshinone IIA (CAS 568-72-9) is a diterpene quinone extracted from the medicinal plant Salvia miltiorrhiza (Danshen) It modulates cellular signaling by inhibiting the binding of transcription factors NF- B and AP-1 to DNA thereby regulating gene expression associated with inflammation and proliferation Tanshinone IIA has demonstrated the capacity to suppress -amyloid aggregation and protect neuronal PC12 cells against -amyloid-induced apoptosis It exhibits both antioxidant and anti-inflammatory properties supporting its use in studies related to oncology neurodegeneration and inflammation
Apexbio Technology LLC Tanshinone IIA 568-72-9 20mg
Tanshinone IIA (CAS 568-72-9) is a diterpene quinone extracted from the medicinal plant Salvia miltiorrhiza (Danshen) It modulates cellular signaling by inhibiting the binding of transcription factors NF- B and AP-1 to DNA thereby regulating gene expression associated with inflammation and proliferation Tanshinone IIA has demonstrated the capacity to suppress -amyloid aggregation and protect neuronal PC12 cells against -amyloid-induced apoptosis It exhibits both antioxidant and anti-inflammatory properties supporting its use in studies related to oncology neurodegeneration and inflammation
Medchemexpress LLC Tanshinone I | 568-73-0 | MFCD00210563 | 98.8% | 276.29 g/mol | C18H12O3 | 10 MG
Analytical standard of Tanshinone I supplied as a high-purity reference material for research and analytical use. It is intended for qualitative and quantitative analysis, method development, calibration, and identity/purity testing by techniques such as liquid chromatography, gas chromatography, and mass spectrometry. Reported purity ≈98.8% and CAS 568-73-0.
- Intended for analytical applications such as LC, GC, and MS.
- High purity suitable for calibration and quantitative analysis.
- Useful for method development and identity and purity testing.
- Available in small research quantities for laboratory use.