Diterpenoids
Medchemexpress LLC Tanshinone I | 568-73-0 | MFCD00210563 | 98.8% | 276.29 g/mol | C18H12O3 | 10 MG
Analytical standard of Tanshinone I supplied as a high-purity reference material for research and analytical use. It is intended for qualitative and quantitative analysis, method development, calibration, and identity/purity testing by techniques such as liquid chromatography, gas chromatography, and mass spectrometry. Reported purity ≈98.8% and CAS 568-73-0.
- Intended for analytical applications such as LC, GC, and MS.
- High purity suitable for calibration and quantitative analysis.
- Useful for method development and identity and purity testing.
- Available in small research quantities for laboratory use.
Medchemexpress LLC Tanshinone IIB | 17397-93-2 | 310.34 | 1 MG
Tanshinone IIB is a major active constituent of the roots of Salvia miltiorrhiza (Danshen) which is widely used for the research of stroke and coronary heart disease in Asian countries. It has a neuroprotective effect via inhibition of apoptosis.
Medchemexpress LLC 4,4'-sulfonylbis(2-methylphenol) | 16346-97-7 | MFCD00130281 | 97.0% | 278.32 g/mol | C14H14O4S | 5 MG
This bisphenol-derived small-molecule inhibits DNA topoisomerase II alpha and is intended for research use. It demonstrates topo II inhibitory activity and in vitro cell growth inhibition, making it suitable for biochemical and anticancer studies.
- Small-molecule inhibitor of DNA topoisomerase II alpha.
- Bisphenol-derived structure; formula C14H14O4S.
- Documented in vitro topo II inhibitory activity and cell growth IC50 values.
- Supplied in small quantities for research use (5 mg pack).
- Intended for biochemical and anticancer research applications.
Medchemexpress LLC HY-N0134 5mg Medchemexpress, Tanshinone I CAS:568-73-0 Purity:>98%
Medchemexpress, HY-N0134 5mg Tanshinone I CAS:568-73-0 Tanshinone I is an inhibitor of type IIA human recombinant sPLA 2 ( IC 50 =11 μM) and rabbit recombinant cPLA 2 ( IC 50 =82 μM). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Tanshinone IIA anhydride | 61077-78-9 | 310.34 | 1 MG
Tanshinone IIA anhydride is a potent and irreversible human carboxylesterase (CE) inhibitor. It has Ki values of 1.9 nM for human CE1 and 1.4 nM for human intestinal CE (hiCE).
- Potent and irreversible human carboxylesterase (CE) inhibitor
- Ki values of 1.9 nM for human CE1
- Ki values of 1.4 nM for human intestinal CE (hiCE)
Medchemexpress LLC HY-N0360 10mg Medchemexpress, Dihydrotanshinone I CAS:87205-99-0 Purity:>98%
Medchemexpress, HY-N0360 10mg Dihydrotanshinone I CAS:87205-99-0 Dihydrotanshinone I is a natural compound extracted from Salvia miltiorrhiza Bunge which has been widely used for treating cardiovascular diseases. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Cucurbitacin IIa | 58546-34-2 | 562.73 | 1 MG
Cucurbitacin IIa, also known as Hemslecin A, is an orally active EGFR inhibitor capable of permeating the blood-brain barrier. It demonstrates an IC50 of 1.455 nM against human EGFR and exhibits anti-inflammatory activity by inhibiting the EGFR-MAPK signaling pathway.
Features and Benefits:
- Induces caspase-3-dependent apoptosis.
- Downregulates survivin expression.
- Enhances autophagy levels.
- Disrupts the actin cytoskeleton via actin aggregation.
- Arrests the cell cycle at the G2/M phase.
- Supports research into inflammation-related diseases.
- Useful in studies on depression and cancers like non-small cell lung cancer.
Medchemexpress LLC Tanshinone IIA sulfonate sodium | 69659-80-9 | 396.39 | 5 MG
Tanshinone IIA sulfonate (sodium) is a derivative of tanshinone IIA. It acts as an inhibitor of store-operated Ca2+ entry (SOCE) and is used to treat cardiovascular disorders. This product is for research use only and not sold to patients.
- Inhibits store-operated Ca2+ entry (SOCE)
- Used to treat cardiovascular disorders
- Inhibits hypoxia-induced PKG and PPAR-γ downregulation
- Suppresses TRPC1 and TRPC6 expression in hypoxic PASMCs
- Inhibits CYP3A4 activity
- Attenuates scopolamine-induced cognitive dysfunctions
- Alleviates hypoxia-induced characteristic changes in chronic hypoxia PH rat model
- Prevents peritoneal adhesion
eMolecules 568-72-9 | Tanshinone IIA | MFCD00238692 | 100mg
Ambeed | Tanshinone IIA | 100mg | 552521161 | A104838 | 568-72-9 | MFCD00238692 | 294.350 | C19H18O3
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Sigma Aldrich Fine Chemicals Biosciences Tanshinone IIA United States Pharmacopeia (USP) Reference Standard | 568-72-9 | MFCD00238692 | 20MG
Tanshinone IIA United States Pharmacopeia (USP) Reference Standard | Mol Wt: 294.34 | 568-72-9 | MFCD00238692 | 20MG
Medchemexpress LLC 4,4'-sulfonylbis(2-methylphenol) | 16346-97-7 | MFCD00130281 | 97.0% | 278.32 g·mol-1 | C14H14O4S | 25 MG
Topoisomerase IIα-IN-9 is a bisphenol-derived small-molecule inhibitor of human DNA topoisomerase IIα intended for research use. Reported biochemical activity includes Topo II inhibition (IC50 ≈ 571 μM) and cell growth inhibitory activity in K562 and CHO cells (IC50 ≈ 117 μM and 218 μM, respectively). Molecular formula C14H14O4S and molecular weight 278.32 g·mol-1 are provided; consult the Certificate of Analysis for purity and storage conditions.
- Moderate inhibitor of DNA topoisomerase IIα.
- Exhibits cell growth inhibition in selected cell lines.
- Provided as a characterized small molecule with formula and molecular weight.
- Suitable for biochemical assays and cell-based research applications.
- Certificate of Analysis available for purity and handling details.
