Triterpenoids
Medchemexpress LLC Limonin (Standard) | 1180-71-8 | MFC26H30O8 | 99.1% | 470.51 | 50 MG
Limonin (Standard) is an analytical standard used for research and analytical applications. It exhibits antiviral and antitumor activities, including the inhibition of HIV-1 and induction of apoptosis in human colon adenocarcinoma cells. This standard is commonly employed in qualitative, quantitative, and methodological research experiments.
- Inhibits HIV-1 with an EC50 of 60.0 μM.
- Induces apoptosis in human colon adenocarcinoma cells with an IC50 of 54.74 μM.
- Used in HPLC, GC, and MS applications.
- Appears as a white to off-white solid.
- Classified as a terpenoid and triterpene.
- Initially sourced from plants of the Rutaceae family.
- Functions as an endogenous metabolite.
Medchemexpress LLC HY-N0818 5mg Medchemexpress, Chikusetsusaponin Iva CAS:51415-02-2 Purity:>98%
Medchemexpress, HY-N0818 5mg Chikusetsusaponin Iva CAS:51415-02-2 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC Forskolin, 100mg. Cas: 66575-29-9 MFCD: MFCD00082317. adenylate cyclase activator
Forskolin is a labdane diterpenoid with antihypertensive, positive inotropic, platelet aggregation inhibitory and adenylate cyclase activating properties. 66575-29-9. MFCD00082317
Medchemexpress LLC Lupeol | 545-47-1 | 426.72 | 100 MG
Lupeol is an active pentacyclic triterpenoid with anti-oxidant, anti-mutagenic, anti-tumor, and anti-inflammatory activity. It is a potent androgen receptor (AR) inhibitor and can be used for cancer research, particularly for prostate cancer of androgen-dependent phenotype (ADPC) and castration-resistant phenotype (CRPC).
- Has anti-oxidant activity
- Has anti-mutagenic activity
- Has anti-tumor activity
- Has anti-inflammatory activity
- Potent androgen receptor (AR) inhibitor
- Can be used for cancer research
Apexbio Technology LLC Limonin 1180-71-8 200mg
Limonin (CAS 1180-71-8) is a natural limonoid with inhibitory activities against carcinogenesis and HIV-1 replication It modulates apoptotic signaling pathways to induce apoptosis and suppress HIV-1 replication In in vitro studies limonin demonstrates dose-dependent inhibition of HIV-1 replication with an EC50 of approximately 60 M in human peripheral blood mononuclear cells (PBMCs) and monocyte/macrophage (M/M) cells In human hepatoma HepG2 cells limonin induces apoptosis by affecting relevant signaling pathways Animal studies show that limonin reduces tumor burden and incidence in DMBA-treated Syrian hamsters and inhibits colon adenocarcinoma development in azoxymethane (AOM)-treated rats Based on these pharmacological properties limonin holds research potential in HIV antiviral mechanisms and chemically-induced carcinogenesis models
Selleck Chemical LLC Glycyrrhetinic acid
Glycyrrhetinic acid is a triterpenoid aglycone component of the natural product glycyrrhizinic acid and possesses remarkable anti-proliferative and apoptosis-inducing activity in various cancer cell lines
Medchemexpress LLC 18α-Glycyrrhizic acid | 83896-44-0 | 10 MG
18α-Glycyrrhizic acid is a derivative of Glycyrrhizic acid with weak antihepatotoxic and anti-inflammatory activities. This product is for research use only.
- Purity: 99.79%.
- Appearance: Solid.
- Color: White to off-white.
- Store at -20°C, protected from light. In solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light.
- In vitro solubility: 100 mg/mL in DMSO.
- Two in vivo dissolution protocols available.
Cayman Chemical Betulinic Acid methyl ester, Purity: ≥95%, CAS: 2259-06-5, 5 mg
A triterpenoid and an esterified version of betulinic acid with diverse biological activities; inhibits HIV-1 reverse transcriptase (IC50 = 11 μM); active against L. braziliensis and T. cruzi (IC50s = 69.9 and 93.3 μM, respectively); induces melanogenesis in (EC50 = 2.5 μM) and inhibits the growth of B16 2F2 melanoma cells in vitro (IC50 = 4.9 μM); cytotoxic to SK-LU-1, HepG2, HeLa, SK-MEL-2, and AGS cells (IC50s = 60.84, 77.43, 80.17, 66.17, and 69.94 μg/ml, respectively);
Cayman Chemical 23-hydroxy Betulinic Acid, Purity: ≥98%, CAS: 85999-40-2, 10 mg
A triterpenoid with anticancer activity; inhibits proliferation of K562, B16, and HeLa cells (IC50s = 39.9, 78.5, and 80 µM, respectively), as well as HUVECs (IC50 = 94.8 µM); halts the cell cycle at the S phase and induces apoptosis in K562 cells
AdipoGen Limonin
Chemical. CAS 1180-71-8. Formula C26H30O8. MW 470.51. Synthetic. Limonin is the first described limonoid, which are naturally occurring tetranortriterpenoids that impart bitter flavor in citrus fruits. Compounds belonging to this group have reported anti-proliferative and proapoptotic activity on several cancer cell lines as well as pesticidal, anti-malarial, anti-microbial, anti-HIV, anti-inflammatory, antinociceptive and neuroprotective activity. Shown to inhibit arginase I and II and P-glycoprotein. May be used in assays as control, standard or competitor, or in studies on the physiology, metabolism and biosynthesis of limonin.
Medchemexpress LLC Squalane (Standard) | 111-01-3 | 500 MG
Squalane, a saturated derivative of Squalene, is found in various natural sources including fish oils and certain vegetable oils. It is recognized for its diverse biological activities, encompassing anticancer, antioxidant, skin hydrating, and emollient properties. Research indicates its potential application as a drug carrier and detoxifying agent, with observed effects in both animal models and in vitro studies.
- Purity: 98.0%
- Molecular weight: 422.83
- Formula: C30H62
- Appearance: Colorless to light yellow liquid
- Sourced from animals (fish oils)
- Storage: Pure form -20°C for 3 years, 4°C for 2 years; in solvent -80°C for 6 months, -20°C for 1 month.
- Soluble in DMSO: 100 mg/mL
Medchemexpress LLC Betulinic acid | 472-15-1 | MFCD00009619 | 99.1% | 456.70 g/mol | C30H48O3 | 200 MG
Betulinic acid is a naturally occurring pentacyclic triterpenoid used in research as an apoptosis inducer and bioactive small molecule. It is commonly used in pharmacology and cell biology to probe apoptotic pathways, evaluate anti-inflammatory and antiviral activity, and as a scaffold for synthetic derivatization.
- Natural pentacyclic triterpenoid compound.
- Functions as an apoptosis inducer in cellular assays.
- High purity suitable for research (≈99.1%).
- Available in multiple pack sizes for screening and synthesis workflows.
- Soluble in DMSO for preparation of stock solutions.
Sigma Aldrich Fine Chemicals Biosciences Squalene M.W.: 410.72 | CAS No.: 111-02-4 | MDL No.: MFCD00008912| 1g
Squalene 1G | M.W.: 410.72 | CAS No.: 111-02-4 | MDL No.: MFCD00008912| 1g
TARGETMOL CHEMICALS INC Oleanolic Acid 1G
Also available in 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Oleanolic Acid (Caryophyllin) is a natural compound with anti-tumor activities, which are widely distributed in plants. Purity 98.4%
Cayman Chemical Betulinic Acid, Purity: ≥97%, CAS: 472-15-1, 100 mg
An agonist of the bile acid receptor TGR5 (EC50 = 1 µM) and blocks fatty liver development in cells and mice given ethanol; reduces NF-κB signaling and expression of miR-33 in LPS-treated macrophages, increasing levels of ABCA1; inhibits replication of HIV-1 (IC50 = 1.4 µM) and has cytotoxic effects against cancer cells