Triterpenoids
Cayman Chemical BetulInIc Aldehyde 5mg
A triterpenoid with diverse biological activities; active against P. falciparum (IC50 = 6.5 μg/ml) and M. tuberculosis (MIC = 25 μg/ml) in vitro, as well as laboratory and clinical isolates of methicillin-resistant and -sensitive S. aureus (MICs = 128-512 and 8-512 μg/ml, respectively); inhibits dengue virus NS5 RNA-dependent RNA polymerase (IC50 = 6.1 μM) and inhibits dengue virus type 2 replication by 20 and 55% at 5 and 10 μg/ml, respectively; inhibits growth of leukemia, melanoma, neuroblastoma, and normal fibroblast cell lines (IC50s = 1.1-4.9, 9.6-10.6, 7.5-8.8, and 18.5 μM, respectively)
Medchemexpress LLC Betulinic acid | 472-15-1 | MFCD00009619 | 99.2% | 456.7 g/mol | C30H48O3 | 100 MG
Betulinic acid is a natural pentacyclic triterpenoid (CAS 472-15-1) provided as an analytical reference standard for research and analytical applications. It is used as a qualitative and quantitative standard in method development and validation for HPLC, GC, and MS, and is reported to have biological activities including anti-HIV, anti-malarial, anti-inflammatory, and anti-tumor effects.
- High reported purity for analytical applications.
- Suitable for HPLC, GC, and MS method development.
- Intended for qualitative and quantitative reference standards.
- Supplied as a solid reference material with defined sizes.
- Supports research into multiple biological activities.
AdipoGen Forskolin, 66428-89-5, MFCD00082317, 1 mg
MF: C22H34O7, MW: 410.5, ≥99%, Appearance: White to off-white solid. Potent, cell permeable adenylyl cyclase activator. Increases intracellular cAMP levels. Widely used tool to investigate cAMP as a second messenger. Inotropic and antihypertensive. Smooth muscle relaxant/vasodilator.
Cayman Chemical BetulInIc AcId 50mg
An agonist of the bile acid receptor TGR5 (EC50 = 1 µM) and blocks fatty liver development in cells and mice given ethanol; reduces NF-κB signaling and expression of miR-33 in LPS-treated macrophages, increasing levels of ABCA1; inhibits replication of HIV-1 (IC50 = 1.4 µM) and has cytotoxic effects against cancer cells
Medchemexpress LLC Glycyrrhizic acid (standard) | 1405-86-3 | 97.5% | 10 MG
Glycyrrhizic acid (standard) is an analytical reference material of glycyrrhizic acid intended for method development, calibration, and compound identification in analytical workflows. Supplied as a solid in small mass packages, it is suitable for HPLC and LC-MS reference use. CAS 1405-86-3; molecular weight 822.93 g/mol; formula C42H62O16.
- Intended for analytical applications such as HPLC and LC-MS calibration.
- Provided as a solid reference standard in small mass packs (10 MG).
- Identified by CAS 1405-86-3 and molecular weight 822.93 g/mol.
- Used for quality control and compound identification.
- Batch-specific purity and certificate of analysis available on request.
Medchemexpress LLC Limonin | 1180-71-8 | 99.4% | 470.51 | 100 MG
Limonin inhibits HIV-1 with an EC50 of 60.0 μM. It induces human colon adenocarcinoma cells apoptosis with an IC50 of 54.74 μM. Limonin possesses antiviral and antitumor activities, making it relevant for research in infection and cancer.
- Inhibits HIV-1.
- Induces apoptosis in human colon adenocarcinoma cells.
- Exhibits antiviral and antitumor activities.
- Targets HIV.
- Targets apoptosis.
- Targets endogenous metabolite.
- Targets cytochrome P450.
- Targets P-glycoprotein.
Medchemexpress LLC Squalene | 111-02-4 | 410.72 | 50 MG
Squalene is an intermediate product in the synthesis of cholesterol. It exhibits several pharmacological properties, including hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumor activities. It is for research use only.
- Decreases intracellular ROS level
- Prevents H2O2-induced oxidative injury
- Protects against oxidative DNA damage in MCF10A epithelial cells
- Increases high density lipoprotein-cholesterol and paraoxonase 1 in mice
- Decreases oxidative stress in mice