Triterpenoids
Medchemexpress LLC Lupeol (Clerodol; Monogynol B; Fagarasterol) | 545-47-1 | 426.72 | 25 MG
Lupeol is an active pentacyclic triterpenoid with anti-oxidant, anti-mutagenic, anti-tumor, and anti-inflammatory activities. It is also a potent androgen receptor (AR) inhibitor and is used for cancer research, particularly for androgen-dependent phenotype (ADPC) and castration-resistant phenotype (CRPC) prostate cancer.
- Active pentacyclic triterpenoid
- Anti-oxidant activity
- Anti-mutagenic activity
- Anti-tumor activity
- Anti-inflammatory activity
- Potent androgen receptor (AR) inhibitor
- Can be used for cancer research, especially prostate cancer of ADPC and CRPC phenotypes
Medchemexpress LLC Lupeol acetate | 1617-68-1 | MFCD00017362 | 98.0% | 468.75 g/mol | C32H52O2 | 10MG
Lupeol acetate is a triterpenoid acetate supplied as an analytical research standard for use in chemical and biological research. It serves as a reference material for analytical assays and research into anti-inflammatory, antibacterial, and anticancer activities. A certificate of analysis is provided for batch-specific storage and handling recommendations.
- CAS number 1617-68-1
- Chemical formula C32H52O2
- Molecular weight 468.75 g/mol
- Purity 98.0% (NMR)
- Intended for use as an analytical standard and reference material
- Certificate of analysis available for batch-specific storage and handling
eMolecules 67416-61-9 | (3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bS)-3-Acetoxy-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4-carboxylic acid | MFCD03788777 | 10mg
Ambeed | (3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bS)-3-Acetoxy-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4-carboxylic acid | 10mg | 524995179 | A106831 | 67416-61-9 | MFCD03788777 | 512.731 | C32H48O5
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Apexbio Technology LLC Oleanolic acid(Synonyms: Oleanic acid, Caryophyllin, Astrantiagenin, Giganteumgenin, Caryophyllinic acid, 3β-Hydroxyolean-12-en-28-oic acid), 100mg, CAS: 508-02-1.
Oleanolic acid (CAS 508-02-1) is a naturally occurring triterpenoid isolated primarily from garlic and Phytolacca americana It exerts anti-HIV activity through induction of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) enzymes involved in inflammatory and immune responses Due to its mechanism of modulating these targets oleanolic acid serves as a valuable compound in biomedical research aimed at exploring novel antiviral strategies and immune pathway modulation
Enzo Life Sciences Betulinic acid (~95%) (1g). CAS: 472-15-1
Antitumor and anti-HIV agent. Induces apoptosis by activating mitochondrial permeability transition (MPT). Inhibits NF-κB activation and NF-κB-regulated gene expression induced by carcinogens and inflammatory stimuli. Decreases expression of Bcl-2 and cyclin D1. Potent proteasome activator. Alternative name: 3beta-Hydroxy-20(29)-lupaene-28-oic acid. Purity: ≥90% (HPLC). Appearance: White to off-white powder. Solubility: Soluble in DMSO. Long Term Storage: +4°C.
Medchemexpress LLC 18β-Glycyrrhetinic acid | 471-53-4 | 99.88% | 470.68 | 5 G
18β-Glycyrrhetinic acid is the major bioactive component of Glycyrrhiza uralensis and Glycyrrhizae Radix, known for its anti-ulcerative, anti-inflammatory, and antiproliferative properties. In vitro studies show it suppresses cell proliferation in a dose-dependent manner and influences PARP levels. In vivo, low-dose administration has demonstrated hepatoprotective effects against Triptolide-induced lesions and suppresses cytokine release.
- Exhibits anti-ulcerative, anti-inflammatory, and antiproliferative properties
- Suppresses cell proliferation in various cell lines in a dose-dependent manner
- Decreases full-length PARP levels and increases cleaved-PARP levels
- Demonstrates hepatoprotective effects against Triptolide-induced lesions in rats
- Suppresses cytokine release in animal models
- Applicable for cell assays with primary microglia cultures
- Suitable for animal administration studies
Medchemexpress LLC 18α-Glycyrrhizic acid | 83896-44-0 | 50 MG
18α-Glycyrrhizic acid is a derivative of Glycyrrhizic acid. It exhibits weak antihepatotoxic and anti-inflammatory activities.
- Molecular weight: 822.93
- Formula: C42H62O16
- Appearance: Solid
- Color: White to off-white
- Structure classification: Ketones, aldehydes, acids
- Initial source: Plants, specifically Leguminosae, Glycyrrhiza glabra Linn.
- Purity: 99.79%
- In vitro solubility: DMSO: 100 mg/mL (121.52 mM; requires ultrasonic; hygroscopic DMSO significantly impacts solubility, use newly opened DMSO)
Medchemexpress LLC Oleanolic acid 28-O-β-D-glucopyranoside | 14162-53-9 | 5 MG
Oleanolic acid 28-O-β-D-glucopyranoside is an orally active pentacyclic triterpenoid compound with anti-inflammatory effects. It inhibits inflammatory responses, enhances intestinal epithelial barrier function, and modulates gut microbiota in ulcerative colitis models. Its mechanism of action is related to the PI3K-AKT and MAPK signaling pathways and can be used in research for diseases such as colitis.
- Orally active pentacyclic triterpenoid compound with anti-inflammatory effects
- Inhibits inflammatory responses and modulates gut microbiota
- Enhances intestinal epithelial barrier function
- Targets IL-6 and COX-2 pathways
- Increases transepithelial electrical resistance (TEER) and tight junction protein expression in Caco-2 cells
- Reduces inflammatory cytokines (IL-6, TNF-α, COX-2, iNOS) in Caco-2 cells
- Ameliorates ulcerative colitis in mouse models by reducing inflammation and improving colon health
Cayman Chemical BetulInIc Aldehyde 1mg
A triterpenoid with diverse biological activities; active against P. falciparum (IC50 = 6.5 μg/ml) and M. tuberculosis (MIC = 25 μg/ml) in vitro, as well as laboratory and clinical isolates of methicillin-resistant and -sensitive S. aureus (MICs = 128-512 and 8-512 μg/ml, respectively); inhibits dengue virus NS5 RNA-dependent RNA polymerase (IC50 = 6.1 μM) and inhibits dengue virus type 2 replication by 20 and 55% at 5 and 10 μg/ml, respectively; inhibits growth of leukemia, melanoma, neuroblastoma, and normal fibroblast cell lines (IC50s = 1.1-4.9, 9.6-10.6, 7.5-8.8, and 18.5 μM, respectively)
Selleck Chemical LLC COLFORSIN-100MG
Colforsin, 100MG, CAS# 66575-29-9, MFCD00082317 *For Research & Development use only. Product is not intended for drug, household, or human consumption.