Formic Acid
Formic acid (HCOOH) is naturally-occurring, flammable, corrosive, organic, and the simplest carboxylic acid. Used as a hydride ion source in synthetic organic chemistry, a mobile phase component in HPLC, a preservative/antibacterial agent in agriculture, etc.
Formic or methanoic acid (CAS: 64-18-6; PubChem ID: 284) is a colorless organic acid with the formula HCOOH. At ambient temperatures, it has a strong, penetrating odor, like acetic acid. Used in chemical synthesis as an intermediate, this simple carboxylic acid is miscible in water and most organic solvents and is somewhat hydrocarbon-soluble.
Formic acid occurs naturally in the venom of some ants and bees. Formate, the conjugate base of formic acid, also occurs naturally in bodily fluids following methanol poisoning.
Formic acid is a source of hydride ion in synthetic organic chemistry, as in the Eschweiler-Clarke and Leuckart-Wallach reactions. It is also a useful component of the mobile phase in reversed-phase high-performance liquid chromatography (RP-HPLC) for peptides, proteins, and intact viruses.
Although formic acid is easily metabolized and eliminated, it can have toxic effects. Methanol metabolism produces formic acid and formaldehyde, which are responsible for the optic nerve damage that results from methanol poisoning. Chronic exposure in humans may cause kidney damage and skin allergies in some people.
In diluted forms, formic acid and formate esters are used as artificial flavorings and perfume additives. In higher concentrations, formic acid is flammable, and skin and eye contact with concentrated liquid or vapors is dangerous.
In agriculture, formic acid is used as a preservative and antibacterial agent and by beekeepers to kill mites. It is useful in leather tanning, textile dyeing and finishing, and in rubber production. Formic acid replaces mineral acids in limescale removers and other cleaning products.
Medchemexpress LLC Pkciota-IN-2 formic | 99.0% | 402.36 | C25H23N5O3 | 5 MG
PKCiota-IN-2 formic is a research-grade small-molecule inhibitor targeting atypical protein kinase C iota (PKCι). It exhibits low-nanomolar potency and a defined selectivity profile, and is supplied as a powder for laboratory use with recommended sealed, refrigerated storage.
- Low-nanomolar potency against PKCι (IC50 2.8 nM).
- Inhibits PKCα and PKCε with higher IC50s (71 nM and 350 nM).
- High chemical purity (99.04%).
- Molecular weight 402.36 g·mol⁻¹.
- Provided as a powder with refrigerated storage recommended.
- Available in small research pack sizes (including 5 mg).
Sigma Aldrich Fine Chemicals Biosciences Formic acid reagent grade, >=95% | 64-18-6 | MFCD00003297 | 100ML
Formic acid reagent grade, >=95% | Purity: >=95% | Mol Wt: 46.03 | 64-18-6 | MFCD00003297 | 100ML
eMolecules Oakwood Chemicals Formic Acid ACS Grade 4kg 480143865 093996 0 000 64-18-6 MFCD00003297 46 025 CH2O2
Oakwood Chemicals Formic Acid ACS Grade 4kg 480143865 093996 0 000 64-18-6 MFCD00003297 46 025 CH2O2
Sigma Aldrich Fine Chemicals Biosciences FORMIC ACID 98-100%,1L
Formic acid 98-100% | CAS No: 64-18-6 | Linear Formula: HCOOH | Molecular Weight: 46.03 | 1 liter
Medchemexpress LLC Dl-01 formic | 2964513-44-6 | 98.5% | 1144.30 | C56H73N9O15S | 5 MG
DL-01 formic is a drug-linker conjugate used in the synthesis of antibody-drug conjugates (ADCs) and related research applications. It is supplied as a high-purity solid for laboratory research use only and should be handled and stored according to the product datasheet and safety documentation.
- Drug-linker conjugate for ADC synthesis
- High purity (approximately 98.5%) solid, white to light yellow
- Molecular formula C56H73N9O15S and molecular weight 1,144.30
- CAS number 2964513-44-6
- Store at -80°C, protect from light, store under nitrogen
Medchemexpress LLC Bisindolylmaleimide IX formic | 00-00-0 | 96.0% | 503.57 g/mol | C26H25N5O4S | 5 MG
Ro 31-8220 formic is the formic acid salt of bisindolylmaleimide IX, a potent protein kinase C (PKC) inhibitor provided for laboratory research. The compound is supplied as a small, high-purity solid with manufacturer storage and handling guidance available on the product datasheet.
- Potent PKC inhibitor with low-nanomolar activity.
- Formic acid salt for improved handling and solubility options.
- High purity (≈96.0%).
- Orange to red solid appearance.
- Supplied as a 5 mg vial for research use.
- Recommended storage: sealed, away from moisture, at -20 °C; in solvent, store at -80 °C (up to 6 months) or -20 °C (up to 1 month).
![eMolecules Formic Acid[for LC-MS] | TCI America | 64-18-6 | MFCD00003297 | 46.025 | CH2O2 | 98.000 | OC=O | 25ml | 115078985](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC2396979.JPG-250.jpg)
eMolecules Formic Acid[for LC-MS] | TCI America | 64-18-6 | MFCD00003297 | 46.025 | CH2O2 | 98.000 | OC=O | 25ml | 115078985
Formic Acid[for LC-MS] | TCI America | 64-18-6 | MFCD00003297 | 46.025 | CH2O2 | 98.000 | OC=O | 25ml | 115078985