Alkyl chlorides
Medchemexpress LLC 2-Chloro-5-(trifluoromethyl)pyrimidine | 69034-12-4 | 182.53 | 25 G
2-Chloro-5-(trifluoromethyl)pyrimidine is a white to light yellow solid that serves as a drug intermediate for the synthesis of various active compounds. This product is intended for research use only.
- Purity verified by HPLC at 99.84%
- Molecular weight of 182.53
- Chemical formula C5H2ClF3N2
- Appearance as a white to light yellow solid
- Suitable for synthesis of active compounds
- Long-term stability: powder at -20°C for 3 years, or 4°C for 2 years
- Stability in solvent: -80°C for 6 months, or -20°C for 1 month
Medchemexpress LLC 1-Fluoronaphthalene | 321-38-0 | MFCD00003873 | 96.9% | 146.16 | 250 MG
1-Fluoronaphthalene (Standard) is an organofluorine compound derived from naphthalene derivatives and fluorinated aromatics. It is intended for research and analytical applications, serving as the analytical standard for 1-Fluoronaphthalene. This compound can be used to synthesize LY248686, a potent inhibitor of serotonin and noradrenaline uptake. It is commonly utilized in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
- Analytical standard for 1-Fluoronaphthalene.
- Used in research and analytical applications.
- Can be used to synthesize LY248686.
- Suitable for HPLC, GC, and MS research experiments.
Medchemexpress LLC 1-Fluoronaphthalene (standard) | 321-38-0 | 96.9% | 146.16 | 50 MG
1-Fluoronaphthalene (Standard) is the analytical standard of 1-Fluoronaphthalene, intended for research and analytical applications. It is an organofluorine compound derived from naphthalene derivatives and fluorinated aromatics. This compound can be used to synthesize LY248686, a potent inhibitor of serotonin and noradrenaline uptake.
- Used as an analytical standard.
- Commonly employed in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
Medchemexpress LLC 1-Fluoronaphthalene (standard) | 321-38-0 | 96.9% | 146.16 | 25 MG
1-Fluoronaphthalene (Standard) is an analytical standard intended for research and analytical applications. It is an organofluorine compound derived from naphthalene derivatives and fluorinated aromatics. This compound can be used to synthesize LY248686, a potent inhibitor of serotonin and noradrenaline uptake.
- Analytical standard for reference assays.
- Used in qualitative, quantitative, and methodological research experiments.
- Suitable for techniques such as HPLC, GC, and MS.
Medchemexpress LLC 1-Fluoronaphthalene | 321-38-0 | 96.9% | 146.16 | 100 MG
1-Fluoronaphthalene is the analytical standard of 1-Fluoronaphthalene, intended for research and analytical applications. It is an organofluorine compound derived from naphthalene derivatives and fluorinated aromatics. This compound can be used to synthesize LY248686, a potent inhibitor of serotonin and noradrenaline uptake.
- The compound is the grade of analytical standard, which is the reference standard supplied assay.
- It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Medchemexpress LLC 3,5,6-trichloro-2-pyridinol | 6515-38-4 | MFCD00130269 | 99.9% | 198.43 g·mol⁻¹ | C5H2Cl3NO | 1 ML
3,5,6-Trichloro-2-pyridinol is supplied as a 10 mM solution in DMSO (1 mL) for research and analytical use. The compound has CAS 6515-38-4 and a molecular weight of 198.43 g·mol⁻¹. Follow recommended storage guidelines for solution and powder to maintain stability.
- High purity (99.85%).
- Ready-to-use 10 mM solution in DMSO.
- Compact 1 mL vial for small-scale assays.
- Suitable for analytical and research applications.
- Recommended storage: in solvent -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC TL13-112 | 2229037-19-6 | MFCD12922943 | 98.0% | 1002.57 | C49H60ClN9O10S | 10MM 1ML
TL13-112 is a proteolysis targeting chimera (PROTAC) designed to selectively induce degradation of anaplastic lymphoma kinase (ALK) in cellular models. It is supplied as a solid and as a 10 mM solution in DMSO for use in preclinical degradation studies, mechanistic assays, and target validation workflows.
- Selective ALK degradation in cellular assays.
- High purity suitable for biological studies.
- Available as solid or 10 mM DMSO solution for convenient dosing.
- Recommended storage conditions for powder and solvent preparations.
- Applicable to mechanistic studies and preclinical target validation.
Medchemexpress LLC Rapastinel trifluoroacetate | 1435786-04-1 | MFCD20527320 | 98.0% | 527.49 | C20H32F3N5O8 | 10 MG
Rapastinel trifluoroacetate is a peptide-based NMDA receptor modulator used in preclinical research to investigate antidepressant-related mechanisms and receptor pharmacology. It is supplied as a white to off-white solid with high purity and defined storage recommendations.
- High purity (98.0%) suitable for research applications.
- Peptide NMDA receptor modulator with glycine-site partial agonist activity.
- White to off-white solid, convenient for formulation and dosing.
- Available in small milligram quantities for in vitro and in vivo studies.
- Recommended storage: sealed, away from moisture; in solvent -80°C (up to 6 months).
Medchemexpress LLC Spi-112 | 1051387-90-6 | MFCD31620831 | 98.0% | 468.46 g/mol | C22H17FN4O5S | 1 ML
SPI-112 is a potent, selective, and competitive inhibitor of SHP2 (PTPN11) used for in vitro biochemical and biophysical studies. It inhibits SHP2 with an IC50 of approximately 1 μM, with weaker activity against related phosphatases. Kinetic and binding data indicate competitive inhibition (Ki ≈ 0.8 μM) and 1:1 binding by SPR (KD ≈ 1.3 μM). The compound is not cell permeable and is supplied for research applications.
- Inhibits SHP2 with IC50 ≈ 1 μM.
- Shows selectivity over related phosphatases (IC50s 18.3 μM for PTP, 14.5 μM for PTP1B).
- Exhibits competitive inhibition kinetics (Ki ≈ 0.8 μM).
- Binds 1:1 in SPR with KD ≈ 1.3 μM.
- Not cell permeable due to polar or charged functional groups.
- Supplied as a solid and as a 10 mM solution for in vitro assays.
- High purity suitable for biochemical assays (≈98%).
- Store solid at 4°C; in solvent store at -80°C (long term) or -20°C (short term).