Halomethanes
Medchemexpress LLC TEPC466 | 2621957-88-6 | 99.4% | 544.60 | 50 MG
TEPC466 is a novel TEPP-46-based aggregation-induced emission (AIE) probe that shows high selectivity and sensitivity for detecting the PKM2 protein via the AIE effect. It can be used for PKM2 detection and has been successfully applied in imaging the PKM2 protein in colorectal cancer cells with low toxicity. It is a useful tool for cancer diagnosis and research.
- Novel TEPP-46-based aggregation-induced emission (AIE) probe
- High degree of selectivity and sensitivity for the detection of PKM2 protein
- Successfully applied in imaging PKM2 protein in colorectal cancer cells with low toxicity
- Useful tool for cancer diagnosis and research
Medchemexpress LLC Aryl Hydrocarbon Receptor Antibody (YA610) | Predicted band size: 96 kDa; Observed band size: 105 kDa | 50 UL
Aryl Hydrocarbon Receptor Antibody (YA610) is a rabbit-derived, non-conjugated IgG monoclonal antibody, specifically targeting the Aryl Hydrocarbon Receptor. It is for research use only and not intended for patient use.
- Rabbit-derived recombinant monoclonal antibody
- Targets human Aryl Hydrocarbon Receptor
- Validated for Western Blot and Immunocytochemistry/Immunofluorescence
- Supplied as a liquid in TBS with BSA, glycerol, and sodium azide preservative
- Store at -20°C for up to 1 year
- Plays a role in development, immunity, and cancer
- Regulates angiogenesis, hematopoiesis, and metabolism
- Functions as a ligand-activated transcription factor
- Subcellular localization in cytoplasm and nucleus
eMolecules ChemScene / 4-Chloro-N-hydroxybenzamide / 100mg / 714103995 / CS-0145140 / 0.000 / 1613-88-3 / MFCD03551074 / 171.580 / C7H6ClNO2
ChemScene / 4-Chloro-N-hydroxybenzamide / 100mg / 714103995 / CS-0145140 / 0.000 / 1613-88-3 / MFCD03551074 / 171.580 / C7H6ClNO2
eMolecules AstaTech / POTASSIUM PHENYL SULFATE / 0.25g / 448280741 / T71922 / 98.000 / 1733-88-6 / MFCD00070590 / 212.260 / C6H5KO4S
AstaTech / POTASSIUM PHENYL SULFATE / 0.25g / 448280741 / T71922 / 98.000 / 1733-88-6 / MFCD00070590 / 212.260 / C6H5KO4S
Medchemexpress LLC N-(4-((4-isopropylpiperazin-1-yl)sulfonylphenyl)-5-pentafluorophenyl)nicotinamide | 1803003-65-7 | 99.9% | 513.54 | 5 MG
RN-1665 is an orally active TRPV4 antagonist that exhibits excellent selectivity for related TRP receptors such as TRPV1, TRPV3, and TRPM8. RN-1665 is a TRPV4 probe for focus screens, with IC50s of 0.26 μM and 0.39 μM for hTRPV4 and rTRPV4 from human and rat, respectively.
- IC50 for human TRPV4 is 0.26 μM.
- IC50 for rat TRPV4 is 0.39 μM.
- Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 minutes.
- Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 minutes.
- Pharmacokinetic analysis has been performed in Wistar rats.
eMolecules 6,7-Dibromobenzo(1,4)dioxan | 25812-80-0 | MFCD00463506 | 1g
Combi-Blocks | 6,7-Dibromobenzo(1,4)dioxan | 1g | 117543164 | OT-1148 | 97.000 | 25812-80-0 | MFCD00463506 | 293.942 | C8H6Br2O2
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Medchemexpress LLC Myrcene (β-Myrcene) | 123-35-3 | 136.23 | 5 G
Myrcene (β-Myrcene) is an aromatic compound that inhibits TNFα and NF-κB activity. It possesses anti-invasive action, inhibits the cell cycle, and induces apoptosis in cancer cells. Additionally, Myrcene demonstrates strong blood protection effects, anti-inflammation, and anti-inflammatory activity.
- Inhibits TNFα and NF-κB activity
- Possesses anti-invasive properties
- Inhibits the cell cycle
- Induces apoptosis in cancer cells
- Demonstrates strong blood protection effects
- Anti-inflammation and anti-inflammatory activities
Medchemexpress LLC 1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7R)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)- | 2413020-56-9 | 99.9% | 476.53 | 25 MG
BAY-593 is an orally active GGTase-I inhibitor. It can block YAP1/TAZ signaling in animals and has antitumor activity.
- Orally active GGTase-I inhibitor
- Blocks YAP1/TAZ signaling in animals
- Exhibits antitumor activity
- Inhibits proliferation of HT-1080 and MDA-MB-231 cells with IC50 values of 0.038 and 0.564 μM, respectively
- Shows dose-dependent antitumor activity in HT-1080 fibrosarcoma and MDA-MB-231 triple negative breast cancer xenotransplantation mouse models
Medchemexpress LLC Demethylzeylasteral | 107316-88-1 | 480.59 | 20 MG
Demethylzeylasteral | 107316-88-1 | 480.59 | 20 MG
eMolecules AstaTech / 5-(4-CHLOROBENZAMIDO)-2-ETHOXYBENZENE-1-SULFONYL CHLORIDE / 0.1g / 721754411 / AB1324 / 95.000 / 680617-88-3 / MFCD03424955 / 374.230 / C15H13Cl2NO4S
AstaTech / 5-(4-CHLOROBENZAMIDO)-2-ETHOXYBENZENE-1-SULFONYL CHLORIDE / 0.1g / 721754411 / AB1324 / 95.000 / 680617-88-3 / MFCD03424955 / 374.230 / C15H13Cl2NO4S
Medchemexpress LLC MPP+ (iodide) | 36913-39-0 | 99.96% | 297.14 | 25 MG
MPP+ iodide is a toxic metabolite of the neurotoxin MPTP. It causes symptoms of Parkinson's disease in animal models by selectively destroying dopaminergic neurons in the substantia nigra. The compound is taken up by the dopamine transporter into dopaminergic neurons, where it exerts its neurotoxic action on mitochondria by affecting complex I of the respiratory chain. It is also a high-affinity substrate for the serotonin transporter (SERT).
- Toxic metabolite of neurotoxin MPTP
- Causes Parkinson's disease symptoms in animal models
- Selectively destroys dopaminergic neurons in the substantia nigra
- Taken up by the dopamine transporter
- Exerts neurotoxic action on mitochondria by affecting complex I of the respiratory chain
- High-affinity substrate for the serotonin transporter (SERT)
eMolecules ChemScene / 5-(Trifluoromethyl)pyridazin-3-amine / 50mg / 582640721 / CS-W022265 / 0.000 / 1211591-88-6 / MFCD20726836 / 163.103 / C5H4F3N3
ChemScene / 5-(Trifluoromethyl)pyridazin-3-amine / 50mg / 582640721 / CS-W022265 / 0.000 / 1211591-88-6 / MFCD20726836 / 163.103 / C5H4F3N3
Medchemexpress LLC CCL4 Human 100ug
CCL4 Protein Human is a small cytokine of the CC chemokine subfamily that binds to the CCR5 chemokine receptor on the cell surface promotes leukocyte aggregation under various inflammatory conditions and contributes to immune protection against human immunodeficiency virus type 1 CCL4 Protein Human is a recombinant human CCL4 (A24-N92) expressed by E coli[1]
eMolecules AstaTech / N-ACETYL-16-DIAMINOHEXANE / 0.1g / 696743659 / D93510 / 95.000 / 49631-88-1 / MFCD00871149 / 158.245 / C8H18N2O
AstaTech / N-ACETYL-16-DIAMINOHEXANE / 0.1g / 696743659 / D93510 / 95.000 / 49631-88-1 / MFCD00871149 / 158.245 / C8H18N2O