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Filtered Search Results
Medchemexpress LLC SOCE inhibitor 1 | 2169316-15-6 | 99.7% | 513.47 | 50 MG
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SOCE inhibitor 1, also known as Compound 39, is a potent store-operated calcium entry (SOCE) inhibitor. It demonstrates good stability in plasma and an IC50 of 4.4 μM, making it suitable for various research applications.
- Potent store-operated calcium entry (SOCE) inhibitor
- IC50 of 4.4 μM
- Good stability in plasma
- White to pink solid appearance
- Purity of 99.73%
- For research use only
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![Medchemexpress LLC 5-Pyrimidineacetic acid, 4,6-bis(dimethylamino)-2-[[4-[[4-(trifluoromethyl)benzoyl]amino]phenyl]methyl]- | 1093108-50-9 | 99.4% | 501.50 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000438367-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC 5-Pyrimidineacetic acid, 4,6-bis(dimethylamino)-2-[[4-[[4-(trifluoromethyl)benzoyl]amino]phenyl]methyl]- | 1093108-50-9 | 99.4% | 501.50 | 25 MG
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BI-671800 is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2), with IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. It has potential for the treatment of poorly controlled asthma.
- Highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2).
- IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively.
- Potential for the treatment of poorly controlled asthma.
- Solid appearance, white to off-white color.
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eMolecules 569-42-6 | NAPHTHALENE-1,8-DIOL | AstaTech | MFCD00042701 | 160.172 | C10H8O2 | 95.000 | Oc1cccc2cccc(O)c12 | 1g | 233625920
NAPHTHALENE-1,8-DIOL | AstaTech | 569-42-6 | MFCD00042701 | 160.172 | C10H8O2 | 95.000 | Oc1cccc2cccc(O)c12 | 1g | 233625920
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Medchemexpress LLC Clobutinol (hydrochloride) | 1215-83-4 | 99.9% | 292.25 | 1 ML
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Clobutinol hydrochloride is a compound with anti-tussive effects. It affects heart rate and blood pressure and can be used for cough-related research.
- Anti-tussive effects
- Affects heart rate and blood pressure
- Used for cough-related research
- 99.9% purity
- Molecular weight: 292.25
- CAS Number: 1215-83-4
- Harmful if swallowed
- Causes skin irritation
- Causes serious eye irritation
- May cause respiratory irritation
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Medchemexpress LLC BI-2493 | 2937344-16-4 | C24H27N7OS | 100 MG
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BI-2493 is a structural analogue of BI-2865, functioning as a highly selective and orally active pan-KRAS inhibitor. It is utilized in cancer research due to its ability to attenuate tumor growth.
- Highly selective and orally active pan-KRAS inhibitor
- Attenuates tumor growth
- Inhibits proliferation of KRAS mutant cancer cell lines
- Exhibits tumor-suppressive activity in xenograft models
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Medchemexpress LLC Carmoterol (hydrochloride) | 137888-11-0 | 98.7% | 404.89 | 25 MG
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Carmoterol hydrochloride is a highly potent, selective, and long-acting β2-adrenoceptor agonist with a pEC50 of 10.19. It exhibits 53 times higher affinity for β2-adrenoceptors compared to β1-adrenoceptors. This compound is suitable for research related to asthma and chronic obstructive pulmonary disease (COPD).
- Highly potent, selective, and long-acting β2-adrenoceptor agonist.
- 53 times higher affinity for β2-adrenoceptors than for β1-adrenoceptors.
- Can be used for the research of asthma and chronic obstructive pulmonary disease (COPD).
- High purity: 98.73%.
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Medchemexpress LLC KTX-582 | 2573298-13-0 | 98.7% | 872.93 | 1 MG
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KTX-582 is a potent IRAK4 degrader with DC50 values of 4 nM and 5 nM for IRAK4 and Ikaros, respectively. It can induce apoptosis in MYD88MT DLBCL and is efficient at inducing in vivo tumor regressions in a lymphoma model.
- Potent IRAK4 degrader
- Induces apoptosis in MYD88MT DLBCL
- Efficient at inducing in vivo tumor regressions in lymphoma models
- Degrades IRAK4 in whole blood monocyte and lymphocyte with IC50s of <0.05 μM
- Inhibits IRAK4 in human whole blood LPS TNFα with an IC50 of 0.05-1 μM
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Medchemexpress LLC AES-135 10mM 1mL | 2361659-61-0 | 1 ML
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AES-135 is a hydroxamic acid-based pan-HDAC inhibitor supplied as a 10 mM solution in DMSO (1 mL) for research use only. It shows inhibitory activity against HDAC3, HDAC6, HDAC8, and HDAC11 and is provided with high reported purity and defined storage recommendations.
- Hydroxamic acid-based pan-HDAC inhibitor.
- Inhibits HDAC3, HDAC6, HDAC8, and HDAC11 (reported IC50s in sub-micromolar to low-micromolar range).
- Provided as a 10 mM solution in DMSO, 1 mL.
- Reported purity 98.21%.
- Molecular formula C33H29F6N3O5S; molecular weight 693.66.
- Storage recommendations: powder at -20°C (up to 3 years); solution at -80°C (up to 6 months).
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Selleck Chemical LLC BI-4464
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BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK with an IC50 of 17 nM
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eMolecules 56413-95-7 | dichloropyrazine-2,3-dicarbonitrile | Pharmablock | MFCD00191419 | 198.990 | C6Cl2N4 | 97.000 | Clc1nc(C#N)c(nc1Cl)C#N | 1g | 551283556
dichloropyrazine-2,3-dicarbonitrile | Pharmablock | 56413-95-7 | MFCD00191419 | 198.990 | C6Cl2N4 | 97.000 | Clc1nc(C#N)c(nc1Cl)C#N | 1g | 551283556
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Medchemexpress LLC Seproxetine hydrochloride | 127685-30-7 | MFCD06658520 | 93.1% | 331.76 g·mol⁻1 | C16H17ClF3NO | 100MG
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Seproxetine hydrochloride is the hydrochloride salt of seproxetine (S-norfluoxetine), a selective serotonin reuptake inhibitor (SSRI) and an active metabolite of fluoxetine. Intended for research use in biochemical and pharmacological studies, the compound is provided in multiple small-scale package sizes and is characterized by its molecular formula C16H17ClF3NO, molecular weight 331.76 g·mol⁻1, and CAS 127685-30-7.
- High enantiomeric excess and purity for research applications (97.6% ee; 93.1% purity).
- Available in multiple small package sizes to support screening and synthesis.
- Provided as the hydrochloride salt for improved handling and stability.
- Documented molecular formula and weight for accurate formulation and calculations.
- CAS number included for unambiguous chemical identification.
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Medchemexpress LLC Butenafine (hydrochloride) | 101827-46-7 | 100.0% | 353.93 | 1 ML
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Butenafine Hydrochloride is a synthetic benzylamine antifungal. It works by inhibiting the synthesis of sterols through the inhibition of squalene epoxidase. This drug is used to control dermal fungal infections such as athlete's foot and ringworm. It has excellent penetration into the epidermis and a prolonged retention time, conferring residual therapeutic activity after treatment cessation. Butenafine also possesses anti-inflammatory activity.
- Inhibits squalene epoxidase
- Controls dermal fungal infections
- Provides excellent epidermal penetration
- Offers prolonged retention time
- Possesses anti-inflammatory properties
- Effective for tinea corporis cruris and tinea manuum pedis
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Medchemexpress LLC Butenafine Hydrochloride | 101827-46-7 | 99.9% | 353.93 | 5 G
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Butenafine Hydrochloride | 101827-46-7 | 99.9% | 353.93 | 5 G
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Alkali Scientific Naphthol AS MX phosphate, 100 Mg
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Naphthol AS MX Phosphate (APH002 CP) is a reagent used in laboratory experiments involving enzyme activity assays. This 100mg package is specifically used as a phosphate substrate for enzyme reactions, particularly in histochemistry and cytochemistry studies. The naphthol-based substrate undergoes a colorimetric change when enzymatically cleaved, providing a visible indication of enzyme activity. Naphthol AS MX Phosphate is used to study the activity of phosphatases and other enzymes in cellular and tissue samples. This compound is often employed in diagnostic and research applications, particularly in the study of enzyme-linked immunosorbent assays (ELISA) and other biochemical tests.
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Medchemexpress LLC 1,4-naphthoquinone-d6 | 26473-08-5 | 99.2% | 164.19 g/mol | C10D6O2 | 10 MG
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1,4-Naphthoquinone-d6 is the deuterium-labeled analogue of 1,4-naphthoquinone supplied as a high-purity solid for use as a stable isotope standard, tracer, or analytical reference in mechanistic studies and mass spectrometry. The material is formulated and supplied with storage guidance to maintain isotopic and chemical integrity for laboratory use.
- Deuterium labeled (d6) for isotope tracing and internal standard use.
- High purity suitable for analytical applications (99.2%).
- Solid, light yellow to yellow appearance for easy handling.
- Supplied in small sizes for quality-controlled experiments.
- Storage guidance supports long-term stability of powder and solutions.
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