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Filtered Search Results
Medchemexpress LLC Diphenidol hydrochloride | 3254-89-5 | MFCD00151479 | 99.1% | C21H28ClNO | 1 G
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Diphenidol hydrochloride is a non-selective muscarinic M1-M4 receptor antagonist with anti-arrhythmic activity. It is also a potent non-specific blocker of voltage-gated ion channels (Na+, K+, and Ca2+) in neuronal cells. It can be used in the study of antivertigo and antinausea.
- Acts as a non-selective muscarinic M1-M4 receptor antagonist
- Exhibits anti-arrhythmic activity
- Functions as a potent non-specific blocker of voltage-gated ion channels (Na+, K+, and Ca2+) in neuronal cells
- Inhibits sodium currents and can produce spinal anesthesia
- Shown to reduce neuropathic pain and TNF-α overexpression in rat models
- Demonstrates an inhibitory effect on exercise and morphine-induced vomiting in pica rats
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Aobchem AOBCHEM
5000863771 1 2-DIFLUORO-4- 2-PROPEN-1-YL
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Medchemexpress LLC (R)-1-(Naphthalen-1-yl)ethanamine hydrochloride | 82572-04-1 | 99.8% | C₁₂H₁₄ClN | 1 G
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(R)-1-(Naphthalen-1-yl)ethanamine hydrochloride is a white to off-white solid primarily intended for research use only and has not been fully validated for medical applications.
- Consistent with structure as verified by ¹H NMR spectrum and LCMS.
- High purity of 99.84% (LCMS).
- Store at 4°C under nitrogen.
- For solvent solutions, store at -80°C for 6 months or -20°C for 1 month under nitrogen.
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Medchemexpress LLC (R)-N-(1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propanamide | 1005450-55-4 | 99.1% | C22H20F3NO | 1 G
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This product is a drug intermediate used for the synthesis of various active compounds. It is supplied as a white to off-white solid with high purity, ensuring reliability for laboratory applications. This substance is intended for research use only and is not for medical applications or sale to patients.
- Used as a drug intermediate for synthesizing active compounds
- Solid, white to off-white appearance
- Purity of 99.1%
- Stable under recommended storage conditions
- For research use only
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Medchemexpress LLC Migalastat (hydrochloride) | 75172-81-5 | 99.7% | 199.63 | 25 MG
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Migalastat hydrochloride (GR181413A) is an orally active α-galactosidase A molecular chaperone. It binds to the active site of unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. Upon dissociation in the acidic environment, Migalastat enables these mutant enzymes to regain biological activity. It exhibits an IC50 and Ki value of 0.04 μM for human α-Gal A.
- Orally active α-galactosidase A molecular chaperone
- IC50 and Ki of 0.04 μM for human α-Gal A
- Facilitates transport and restores activity of mutant α-galactosidase A enzymes
- Reduces Gb3 accumulation and lysosome volume in vitro
- Increases α-Gal A activity in heart, kidney, spleen, and liver in transgenic mice
- Reduces lyso-Gb3 levels in kidney, heart, and skin in transgenic mice
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eMolecules 29671-92-9 | Chloroformamidine Hydrochloride | Accela ChemBio (ASD) | MFCD00035527 | 114.960 | CH4Cl2N2 | 95.000 | Cl.NC(Cl)=N | 25g | 490829087
Chloroformamidine Hydrochloride | Accela ChemBio (ASD) | 29671-92-9 | MFCD00035527 | 114.960 | CH4Cl2N2 | 95.000 | Cl.NC(Cl)=N | 25g | 490829087
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Apexbio Technology LLC Naphthol AS-MX phosphate 1596-56-1 100mg
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Naphthol AS-MX phosphate (CAS 1596-56-1) is a small molecule inhibitor that disrupts the interaction between cAMP response element-binding protein (CREB) and CREB-binding protein (CBP) key components of a transcription factor complex In lung cancer cells it demonstrates antiproliferative effects as evidenced by an IC50 of 3 701 mol/L and inhibits both colony formation and anchorage-independent growth Naphthol AS-MX phosphate is utilized in studies investigating KRAS-mutant lung cancers particularly in the context of chemoresistance and poor prognosis
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000430826 BI-27 SUPPLEMENT 50 50ML
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Medchemexpress LLC Phenformin (hydrochloride) | 834-28-6 | 99.6% | 241.72 | 1 G
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Phenformin hydrochloride is an anti-diabetic agent belonging to the biguanide class, known for its ability to activate AMPK activity. It stimulates the phosphorylation and activation of both AMPKalpha1 and AMPKalpha2 without altering LKB1 activity, and has been shown to increase AMPK activity and phosphorylation in isolated hearts, correlated with increased cytosolic [AMP].
- Activates AMPK activity
- Targets AMPK
- Inhibits mitochondrial complex I more potently than metformin
- Induces apoptosis in LKB1 deficient NSCLC cell lines
- Appears as a white to off-white solid
- High purity of 99.6%
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Selleck Chemical LLC BI-9564
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BI-9564 is a selective inhibitor of BRD9 and BRD7 bromodomains with the IC50 of 75 nM and 3 4 M respectively
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Medchemexpress LLC Gabapentin hydrochloride | 60142-95-2 | 98.0% | C9H18ClNO2 | 100 MG
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Gabapentin hydrochloride is a potent, orally active P/Q type Ca2+ channel blocker. It inhibits neuronal Ca2+ influx and reduces neurotransmitter release. This GABA analog can be used to relieve neuropathic pain.
- Potent, orally active P/Q type Ca2+ channel blocker
- Inhibits neuronal Ca2+ influx
- Reduces neurotransmitter release
- GABA analog for neuropathic pain relief
- Inhibits K+-induced Ca2+ increase in synaptosomes
- Decreases K+-evoked release of aspartate and glutamate
- Reduces K+-evoked noradrenaline release
- Improves cognitive performance in animal models
- Provides analgesic effects in animal models
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Selleck Chemical LLC GSK 5959
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GSK5959 is a potent and selective BRPF1 bromodomain inhibitor with an IC50 of 80 nM and exhibits 100-fold selectivity for BRPF1 over a panel of 35 other bromodomains including BRPF2/3 and BET family bromodomains
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eMolecules 1204580-76-6 | 5-Tributylstannyl-2-trifluoromethylpyridine | Synthonix - Stock | MFCD11109387 | 436.150 | C18H30F3NSn | 96.000 | CCCC[Sn](CCCC)(CCCC)c1ccc(nc1)C(F)(F)F | 500mg | 492245331
5-Tributylstannyl-2-trifluoromethylpyridine | Synthonix - Stock | 1204580-76-6 | MFCD11109387 | 436.150 | C18H30F3NSn | 96.000 | CCCC[Sn](CCCC)(CCCC)c1ccc(nc1)C(F)(F)F | 500mg | 492245331
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Aobchem AOBCHEM
5000863929 2- 4-BROMOPHENYL METHOXY -1 3
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eMolecules 9001-62-1 | Sustine? 131 | Strem Chemicals238.201 | C11H9N3NaO2 | 0.000 | [Na+].OC1=CC(=O)C=C\C1=N\Nc1ccccn1 | 100g | 576207973
Sustine? 131 | Strem Chemicals | 9001-62-1238.201 | C11H9N3NaO2 | 0.000 | [Na+].OC1=CC(=O)C=C\C1=N\Nc1ccccn1 | 100g | 576207973
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