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Filtered Search Results
Medchemexpress LLC Trilaciclib hydrochloride | 1977495-97-8 | >98.0% | 519.47 g/mol | C24H32Cl2N8O | 1 G
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Trilaciclib hydrochloride is the hydrochloride salt of trilaciclib, a potent cyclin-dependent kinase 4/6 (CDK4/6) inhibitor used in preclinical research to study cell-cycle regulation and to evaluate protection against chemotherapy-induced myelosuppression.
- Inhibits CDK4 and CDK6 with low-nanomolar potency (IC50 ≈ 1 nM and 4 nM).
- Aqueous solubility ~0.96 mg/mL after ultrasonic treatment and acidification to pH 1.
- Molecular weight 519.47 g/mol.
- Store sealed at 4°C; in solution store at -80°C (up to 6 months) or -20°C (up to 1 month).
- Commonly provided in small masses suitable for stock solution preparation.
- Reported purity ≥98% in supplier listings.
- Used to investigate mitigation of chemotherapy-induced myelosuppression in vitro and in vivo models.
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eMolecules 1161737-33-2 | ChemScene | 6-Cyclopropyl-3(2H)-pyridazinone | 250mg | 569147518 | CS-W003885 | MFCD16871334 | 136.154 | C7H8N2O
Medchem Express | TEPP-46 | 5mg | 446269233 | HY-18657 | 1221186-53-3 | MFCD23160747 | 372.460 | C17H16N4O2S2
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Selleck Chemical LLC BI-1347 S1058-25mg
BI-1347 is a small molecule inhibitor of Cyclin-dependent kinase 8(CDK8) with IC50 of 1 1 nM
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eMolecules 23665-09-0 | Phenylzinc iodide, 0.50 M in THF | Synthonix | MFCD00671995 | 269.390 | C6H5IZn | 0.000 | [I-].[Zn+]c1ccccc1 | 100ml | 532652965
Phenylzinc iodide, 0.50 M in THF | Synthonix | 23665-09-0 | MFCD00671995 | 269.390 | C6H5IZn | 0.000 | [I-].[Zn+]c1ccccc1 | 100ml | 532652965
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Medchemexpress LLC Rilmazafone hydrochloride | 85815-37-8 | 511.79 | 100 MG
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Rilmazafone hydrochloride is a benzodiazepine (omega) ligand, intended for research use only.
- Solid storage at 4°C
- Sealed storage, away from moisture
- In solvent storage at -80°C for 6 months
- In solvent storage at -20°C for 1 month
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eMolecules Synthonix 2-Chlorophenylzinc iodide 0.50 M in THF 50ml 532652670 C73152 148651-35-8 MFCD01863648 303.830 C6H4ClIZn
Synthonix 2-Chlorophenylzinc iodide 0.50 M in THF 50ml 532652670 C73152 148651-35-8 MFCD01863648 303.830 C6H4ClIZn
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eMolecules 908138-51-2 | 3-Fluoro-5-methylphenyl magnesium bromide, 0.5 M in THF | Synthonix - Stock213.332 | C7H6BrFMg | 0.000 | [Br-].Cc1cc(F)cc([Mg+])c1 | 500ml | 437237243
3-Fluoro-5-methylphenyl magnesium bromide, 0.5 M in THF | Synthonix - Stock | 908138-51-2213.332 | C7H6BrFMg | 0.000 | [Br-].Cc1cc(F)cc([Mg+])c1 | 500ml | 437237243
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eMolecules 131379-38-9 | 3-(Ethoxycarbonyl)phenylzinc bromide, 0.50 M in THF | Synthonix294.450 | C9H9BrO2Zn | 97.000 | [Br-].CCOC(=O)c1cccc([Zn+])c1 | 50ml | 703157780
3-(Ethoxycarbonyl)phenylzinc bromide, 0.50 M in THF | Synthonix | 131379-38-9294.450 | C9H9BrO2Zn | 97.000 | [Br-].CCOC(=O)c1cccc([Zn+])c1 | 50ml | 703157780
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eMolecules 29875-07-8 | 4-Methylbenzylmagnesium chloride, 0.5 M in 2-MeTHF | Synthonix | MFCD01319893 | 164.920 | C8H9ClMg | 0.000 | [Cl-].Cc1ccc(C[Mg+])cc1 | 25ml | 627353683
4-Methylbenzylmagnesium chloride, 0.5 M in 2-MeTHF | Synthonix | 29875-07-8 | MFCD01319893 | 164.920 | C8H9ClMg | 0.000 | [Cl-].Cc1ccc(C[Mg+])cc1 | 25ml | 627353683
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eMolecules 1629082-81-0 | (Cyclobutylmethyl)zinc bromide, 0.50 M in THF | Synthonix214.410 | C5H9BrZn | 0.000 | [Br-].[Zn+]CC1CCC1 | 50ml | 596115980
(Cyclobutylmethyl)zinc bromide, 0.50 M in THF | Synthonix | 1629082-81-0214.410 | C5H9BrZn | 0.000 | [Br-].[Zn+]CC1CCC1 | 50ml | 596115980
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Medchemexpress LLC BI 99179 | 1291779-76-4 | 99.38% | 391.46 | 5 MG
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BI 99179 is a chemical probe that acts as a potent and selective type I fatty acid synthase (FAS) inhibitor with an IC50 of 79 nM. It is a tool compound suitable for in vivo validation of FAS as a target for lipid metabolism-related diseases and shows significant peripheral and central exposure upon oral administration in rats.
- Potent in mouse hypothalamic N-42 cells with an IC50 of 0.6 μM.
- No significant LDH release in cytotoxicity assays up to 30 μM.
- Exhibits antiproliferative efficacy in human glioma GAMG cells.
- Possesses a super pharmacokinetic profile in male Han/Wistar rats.
- For research use only.
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Medchemexpress LLC Lesogaberan hydrochloride | 2925644-17-1 | 98.0% | 177.54 | C3H10ClFNO2P | 1 ML
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Lesogaberan hydrochloride is a potent, selective GABAB receptor agonist provided as a ready-to-use 10 mM solution in DMSO for research applications. It is intended for use in receptor pharmacology, binding, and functional assays to probe GABAB-mediated signaling.
- Potent and selective GABAB receptor agonist.
- Supplied as a 10 mM solution in DMSO suitable for in vitro assays.
- High purity, typically 98.0%, for reproducible results.
- Molecular weight 177.54 g/mol; CAS number 2925644-17-1.
- Suitable for receptor pharmacology, binding, and functional studies.
- Available in multiple formats for experimental flexibility.
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Medchemexpress LLC Cloricromen hydrochl 25mg | 74697-28-2 | 432.34 g/mol | C20H26ClNO5·HCl | 25 MG
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Cloricromen hydrochloride is the hydrochloride salt of cloricromen, a research compound that acts as a platelet aggregation inhibitor used in studies of platelet function and experimental thrombosis.
- High purity (99.82%).
- White solid hydrochloride salt.
- Acts as a platelet aggregation inhibitor for studies of platelet function and experimental thrombosis.
- Suitable for biochemical and pharmacological research.
- Identified by CAS 74697-28-2.
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eMolecules 50525-27-4 | [Ru(bpy)?][Cl]???6H?O | Ambeed | MFCD26940142 | 748.620 | C30H36Cl2N6O6Ru | 98.000 | O.O.O.O.O.O.[Cl-].[Cl-].[Ru++].c1ccc(nc1)-c1ccccn1.c1ccc(nc1)-c1ccccn1.c1ccc(nc1)-c1ccccn1 | 5g | 525000444
[Ru(bpy)?][Cl]???6H?O | Ambeed | 50525-27-4 | MFCD26940142 | 748.620 | C30H36Cl2N6O6Ru | 98.000 | O.O.O.O.O.O.[Cl-].[Cl-].[Ru++].c1ccc(nc1)-c1ccccn1.c1ccc(nc1)-c1ccccn1.c1ccc(nc1)-c1ccccn1 | 5g | 525000444
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eMolecules 368866-31-3 | (S)-N-Fmoc-a-(tetrahydro-2H-pyran-4-yl)glycine | Acrotein ChemBio Inc. | MFCD08272908 | 381.428 | C22H23NO5 | 97.000 | OC(=O)[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C1CCOCC1 | 0.25g | 487532494
(S)-N-Fmoc-a-(tetrahydro-2H-pyran-4-yl)glycine | Acrotein ChemBio Inc. | 368866-31-3 | MFCD08272908 | 381.428 | C22H23NO5 | 97.000 | OC(=O)[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C1CCOCC1 | 0.25g | 487532494
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