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Filtered Search Results
Medchemexpress LLC Scavenger receptor class B member 1 (SR-BI/SCARB1), recombinant human | >95.0% | 10 UG
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Recombinant human scavenger receptor class B member 1 (SR-BI/SCARB1) expressed in HEK293 cells and supplied as a lyophilized C-terminal His-tagged protein. Supplied as a 10 μg lyophilized vial, the product runs at ~70-90 kDa and is >95% pure, suitable for biochemical and cell biology assays requiring recombinant human SR-BI.
- Human sequence P33-Y443, accession Q8WTV0-1.
- C-terminal His tag facilitates purification and detection.
- Expressed in HEK293 for mammalian post-translational modifications.
- Lyophilized with stabilizers (trehalose or mannitol, and Tween 80) for stability.
- Purity >95.0% by reducing SDS-PAGE for consistent performance.
- Reconstitute to ≥100 μg/mL; avoid concentrations below 100 μg/mL in ddH2O.
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AdipoGen N N-Bisphosphonomethylglycin
Chemical. CAS 2439-99-8. Formula C4H11NO8P2. MW 263.08. Synthetic. A glycine-phosphonic acid compound, negatively charged at neutral pH, with immunomodulatory and anti-diabetic properties. Enhances anti-B9-23 TCR-dependent T cell activation by modulating murine class II MHC I-Ag7-mediated B9-23 presentation on APCs. Daily administration of glyphosine is shown to delay the onset of diabetes in NOD mice. Herbicide. A plant growth regulator. Acts as a competitive inhibitor of phoshoenolpyruvate carboxylase in plants.
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Medchemexpress LLC 6-(5-methoxymethyl-pyridin-3-yl)-3,4-dihydro-2H-naphthyridine-1-carboxylic acid amide | 1633009-87-6 | 99.2% | 298.34 | C16H18N4O2 | 25 MG
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The compound is a small-molecule, highly selective aldosterone synthase (CYP11B2) inhibitor with nanomolar potency, used in biochemical and pharmacological research to probe aldosterone synthesis and CYP11B2-mediated pathways. It exhibits reported IC50 values of 2.1 nM for CYP11B2 and 310 nM for CYP11B1, and is supplied as a high-purity solid for laboratory studies.
- Highly selective aldosterone synthase inhibitor with nanomolar potency (CYP11B2 IC50 ≈ 2.1 nM).
- Reduced off-target activity against CYP11B1 (IC50 ≈ 310 nM).
- Molecular formula C16H18N4O2; molecular weight 298.34 g/mol.
- Purity 99.2% as reported by supplier.
- Supplied as a small solid quantity suitable for in vitro and in vivo research (e.g., 25 mg).
- Characterized in peer-reviewed pharmacology studies for selectivity and pharmacodynamics.
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Medchemexpress LLC BI-1808 5mg | 5mg
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BI-1808 is a human IgG1 monoclonal antibody that targets TNFR2by blocking interaction of TNFR2 with ligand TNF- confers Fc R-dependent depletion of Treg and mediates expansion of intratumoral CD8 T cells[1]
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![eMolecules 250737-35-0 | (S)-2-tert-Butoxycarbonylamino-3-methoxy-3-oxopropylzinc iodide, 0.50 M in THF | Synthonix394.510 | C9H16INO4Zn | 0.000 | [I-].COC(=O)[C@@H](C[Zn+])NC(=O)OC(C)(C)C | 25ml | 703157755](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502694894.jpg-250.jpg)
eMolecules 250737-35-0 | (S)-2-tert-Butoxycarbonylamino-3-methoxy-3-oxopropylzinc iodide, 0.50 M in THF | Synthonix394.510 | C9H16INO4Zn | 0.000 | [I-].COC(=O)[C@@H](C[Zn+])NC(=O)OC(C)(C)C | 25ml | 703157755
(S)-2-tert-Butoxycarbonylamino-3-methoxy-3-oxopropylzinc iodide, 0.50 M in THF | Synthonix | 250737-35-0394.510 | C9H16INO4Zn | 0.000 | [I-].COC(=O)[C@@H](C[Zn+])NC(=O)OC(C)(C)C | 25ml | 703157755
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Medchemexpress LLC Trilaciclib hydrochloride | 1977495-97-8 | 99.7% | 519.47 g/mol | C24H32Cl2N8O | 1 MG
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Trilaciclib hydrochloride is the hydrochloride salt of trilaciclib, an orally active CDK4/6 inhibitor supplied as a research-grade analytical standard. It is provided as a light yellow to yellow solid for biochemical, cell-based, and preclinical studies, with documented activity against CDK4 and CDK6 and batch-specific characterization available.
- Orally active CDK4/6 inhibitor for cell-cycle arrest studies.
- High purity suitable for analytical and preclinical research.
- Documented potency: CDK4 IC50 ≈ 1 nM; CDK6 IC50 ≈ 4 nM.
- Solid formulation for ease of handling and storage.
- Batch-specific datasheet and COA available for quality verification.
- Intended for research use only; not for human or clinical use.
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Medchemexpress LLC Paroxetine hydrochloride hemihydrate | 110429-35-1 | >99.96% | 500 MG
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Paroxetine hydrochloride hemihydrate is a potent selective serotonin-reuptake inhibitor, widely used as an antidepressant. This compound also demonstrates GRK2 inhibitory capabilities with an IC50 of 14 μM. It plays a significant role in restraining T cell migration and inhibiting GRK2-induced ERK activation, which contributes to its anti-inflammatory effects by reducing pro-inflammatory cytokines like TNF-α and IL-1β in LPS-stimulated BV2 cells.
- Restrains T cell migration.
- Inhibits GRK2 induced ERK activation.
- Reduces pro-inflammatory cytokines (TNF-α and IL-1β).
- Relieves microglia-mediated neurotoxicity.
- Attenuates symptoms of CIA rats and decreases LV remodeling.
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Medchemexpress LLC BMS-214662 (hydrochloride) | 195981-08-9 | 98.5% | 526.1 | 25 MG
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BMS-214662 hydrochloride is a laboratory chemical that acts as an inhibitor. It is provided as a solid and is stable under recommended storage conditions, suitable for various research applications.
- Stable under recommended storage conditions
- Store at -20°C
- Protect from light
- Store under nitrogen
- Used for laboratory research
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Medchemexpress LLC GSK-5959 | 901245-65-6 | 99.7% | 394.47 | 5 MG
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GSK-5959 is a potent, selective, and cell-permeable BRPF1 bromodomain inhibitor. It exhibits an IC50 of approximately 80 nM, making it suitable for laboratory research.
- Potent BRPF1 bromodomain inhibitor
- Selective and cell-permeable
- IC50 of approximately 80 nM
- Purity of 99.73% (LCMS)
- Appears as a light yellow to yellow solid
- Molecular formula: C22H26N4O3
- Molecular weight: 394.47
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Aobchem 7-Bromo-2-naphthoic acid | ≥95% | CAS 5043-14-1 | C11H7BrO2 | 5g
7-Bromo-2-naphthoic acid | ≥95% | CAS 5043-14-1 | C11H7BrO2 | 5g
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Aobchem 4-Hydroxy-1-naphthoic acid | ≥95% | CAS 7474-97-7 | C11H8O3 | 5g
4-Hydroxy-1-naphthoic acid | ≥95% | CAS 7474-97-7 | C11H8O3 | 5g
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Aobchem 5-Chloro-6-methoxy-2-naphthoic acid | ≥97% | CAS 408327-32-2 | C12H9ClO3 | 500mg
5-Chloro-6-methoxy-2-naphthoic acid | ≥97% | CAS 408327-32-2 | C12H9ClO3 | 500mg
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Aobchem 3-Ethoxy-2-naphthoic acid | ≥97% | CAS 54245-36-2 | C13H12O3 | 250mg
3-Ethoxy-2-naphthoic acid | ≥97% | CAS 54245-36-2 | C13H12O3 | 250mg
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Aobchem 5-Chloro-2-naphthoic acid | ≥95% | CAS 56961-89-8 | C11H7ClO2 | 1g
5-Chloro-2-naphthoic acid | ≥95% | CAS 56961-89-8 | C11H7ClO2 | 1g
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Medchemexpress LLC Di-tert-butyl dicarbonate | 24424-99-5 | MFCD00008805 | 99.8% | 500g
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Di-tert-butyl dicarbonate is a general carboxylation reagent[1]
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