Naphthalenes

Polycyclic aromatic hydrocarbon compounds that consist of ten carbon atoms and eight hydrogen atoms fused into two benzene rings; it is the simplest polycyclic aromatic hydrocarbon.

Search Within Results

3,766 – 3,780 of 5,050 results

3,766

Apexbio Technology LLC Naphthol AS-MX phosphate 1596-56-1 100mg

Naphthol AS-MX phosphate (CAS 1596-56-1) is a small molecule inhibitor that disrupts the interaction between cAMP response element-binding protein (CREB) and CREB-binding protein (CBP) key components of a transcription factor complex In lung cancer cells it demonstrates antiproliferative effects as evidenced by an IC50 of 3 701 mol/L and inhibits both colony formation and anchorage-independent growth Naphthol AS-MX phosphate is utilized in studies investigating KRAS-mutant lung cancers particularly in the context of chemoresistance and poor prognosis

Pricing & Availability

3,767

AdipoGen Naphthol AS-TR phosphate 2Na

Chemical. CAS 4264-93-1. Formula C18H13CINNa2O5P. MW BD9837. Naphthol AS-TR Phosphate is a fluorogenic substrate for acid and alkaline phosphatases. Naphthol AS-TR Phosphate is converted to naphthol AS-TR displaying excitation/emission spectra of 388/512nm. The fluorescence is a quantitative marker of acid and alkaline phosphatase activity. Acid and alkaline phosphatases are often used as clinical markers of disease, since the concentration of human acid and alkaline phosphatases undergo pronounced changes in particular diseases, resulting in unusually high or low concentrations. It is a histochemical substrate commonly used in conjunction with diazonium salts to form a specific azo dye for immunohistology, immunoblotting and dot blot applications. Naphthol AS-TR Phosphate is a cyclic-AMP response element-binding protein CREB-CREB binding protein CBP transcription factor complex inhibitor and a potential therapeutic agent for lung cancer.

Pricing & Availability

3,768

eMolecules 113826-06-5 | (2R)-(-)-Glycidyl tosylate | Ambeed | MFCD00010834 | 228.260 | C10H12O4S | 98.000 | Cc1ccc(cc1)S(=O)(=O)OC[C@H]1CO1 | 1g | 552609531

(2R)-(-)-Glycidyl tosylate | Ambeed | 113826-06-5 | MFCD00010834 | 228.260 | C10H12O4S | 98.000 | Cc1ccc(cc1)S(=O)(=O)OC[C@H]1CO1 | 1g | 552609531

Pricing & Availability

3,769

AdipoGen p-Toluenesulfinic acid Na

Chemical. CAS 824-79-3. Formula C7H7NaO2S. Molecular Weight 178.18. Sodium p-Toluenesulfinate is used as an organic bulding block or intermediate for the preparation of pharmaceuticals and dispersal dyes, as a mild reducing agent and as a polymerization accelerator. It is also used as a discharge medium of dyes and pigments. Used as a photo-redox couple together with methylene blue. Further, it serves as a chemical intermediate in the production of fluorescent pigments and fabric adhesive. In addition to this, it is used as an electroplating brightening agent and curing agent.

Pricing & Availability

3,770

eMolecules 866423-24-7 | 5-Benzyloxypentylmagnesium bromide, 0.50 M in THF | Synthonix281.476 | C12H17BrMgO | 0.000 | [Br-].[Mg+]CCCCCOCc1ccccc1 | 25ml | 844919946

5-Benzyloxypentylmagnesium bromide, 0.50 M in THF | Synthonix | 866423-24-7281.476 | C12H17BrMgO | 0.000 | [Br-].[Mg+]CCCCCOCc1ccccc1 | 25ml | 844919946

Pricing & Availability

3,771

eMolecules 72136-49-3 | (9H-Fluoren-2-yl)magnesium bromide, 0.25 M in THF | Synthonix269.424 | C13H9BrMg | 95.000 | [Br-].[Mg+]c1ccc-2c(Cc3ccccc-23)c1 | 50ml | 818572019

(9H-Fluoren-2-yl)magnesium bromide, 0.25 M in THF | Synthonix | 72136-49-3269.424 | C13H9BrMg | 95.000 | [Br-].[Mg+]c1ccc-2c(Cc3ccccc-23)c1 | 50ml | 818572019

Pricing & Availability

3,772

eMolecules 77047-87-1 | 2-Propylzinc bromide, 0.50 M in THF | Synthonix | MFCD06200639 | 188.370 | C3H7BrZn | 0.000 | [Br-].CC(C)[Zn+] | 50ml | 627353731

2-Propylzinc bromide, 0.50 M in THF | Synthonix | 77047-87-1 | MFCD06200639 | 188.370 | C3H7BrZn | 0.000 | [Br-].CC(C)[Zn+] | 50ml | 627353731

Pricing & Availability

3,773

AdipoGen N N-Bisphosphonomethylglycin

Chemical. CAS 2439-99-8. Formula C4H11NO8P2. MW 263.08. Synthetic. A glycine-phosphonic acid compound, negatively charged at neutral pH, with immunomodulatory and anti-diabetic properties. Enhances anti-B9-23 TCR-dependent T cell activation by modulating murine class II MHC I-Ag7-mediated B9-23 presentation on APCs. Daily administration of glyphosine is shown to delay the onset of diabetes in NOD mice. Herbicide. A plant growth regulator. Acts as a competitive inhibitor of phoshoenolpyruvate carboxylase in plants.

Pricing & Availability

3,774

eMolecules 21450-64-6 | 2,6-Dimethylphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | MFCD00192083 | 209.369 | C8H9BrMg | 0.000 | [Br-].Cc1cccc(C)c1[Mg+] | 100ml | 437237107

2,6-Dimethylphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 21450-64-6 | MFCD00192083 | 209.369 | C8H9BrMg | 0.000 | [Br-].Cc1cccc(C)c1[Mg+] | 100ml | 437237107

Pricing & Availability

3,775

Medchemexpress LLC Fedratinib (hydrochloride hydrate) | 1374744-69-0 | 99.9% | 615.62 | 1 G

Fedratinib hydrochloride hydrate is a potent, selective, ATP-competitive, and orally active inhibitor of JAK2. It exhibits an IC50 of 3 nM for both JAK2 and JAK2V617F kinase and demonstrates significant selectivity over JAK1 (35-fold) and JAK3 (334-fold). This compound has been shown to induce apoptosis in cancer cells and is considered to have potential for research in myeloproliferative disorders.

Potent, selective, ATP-competitive, and orally active JAK2 inhibitor.
Targets both JAK2 and JAK2V617F kinase effectively at 3 nM IC50.
Exhibits high selectivity against JAK1 (35-fold) and JAK3 (334-fold).
Induces apoptosis in cancer cells.
Shows promise for research in myeloproliferative disorders.
Inhibits proliferation of cell lines carrying the JAK2V617F mutation.
Reduces STAT5 phosphorylation.

Pricing & Availability

3,776

Medchemexpress LLC 2-Oxa-5-azabicyclo[2.2.1]heptane, 5-[2-[(8aR)-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl]-6-[6-(4-methoxy-3-pyri | 2769715-68-4 | 99.3% | 592.69 | 25 MG

BI-4732 is an orally active, reversible, ATP-competitive EGFR inhibitor with blood-brain barrier penetration. It inhibits the kinase activity of EGFR L858R, T790M, and C797S with IC50 values of 1 nM, while sparing wild-type EGFR. BI-4732 inhibits EGFR and reduces the phosphorylation of AKT, ERK, and S6K. It demonstrates excellent intracranial anti-tumor efficacy in a YU-1097 xenograft model, making it suitable for studying non-small cell lung cancer (NSCLC).

Orally active
Reversible
ATP-competitive EGFR inhibitor
Blood-brain barrier penetration
Inhibits kinase activity of EGFR L858R, T790M, and C797S with IC50 values of 1 nM
Spares wild-type EGFR
Reduces phosphorylation of AKT, ERK, and S6K
Demonstrates intracranial anti-tumor efficacy in YU-1097 xenograft model
Useful for the study of non-small cell lung cancer (NSCLC)

Pricing & Availability

3,777

Apexbio Technology LLC Linagliptin (BI-1356) 668270-12-0 10mg

Linagliptin (BI-1356 CAS 668270-12-0) is a potent competitive inhibitor of dipeptidyl peptidase-4 (DPP-4) demonstrating IC50 values of 0 4 1 1 nM in multiple in vitro assays using DPP-4 extracted from Caco-2 cells DPP-4 is a membrane-bound and soluble protease involved in the degradation of incretin hormones such as GLP-1 which enhance pancreatic -cell glucose sensitivity and insulin secretion Linagliptin displays marked selectivity for DPP-4 over related peptidases and serine proteases In vivo linagliptin dose-dependently inhibits plasma DPP-4 activity and sustains glycemic control with prolonged effects observed at pharmacologically relevant doses This compound is widely utilized in studies of glucose metabolism and -cell function

Pricing & Availability

3,778

eMolecules 171860-66-5 | sec-Butylzinc bromide, 0.50 M in THF | Synthonix | MFCD00671990 | 202.400 | C4H9BrZn | 0.000 | [Br-].CCC(C)[Zn+] | 25ml | 627353532

sec-Butylzinc bromide, 0.50 M in THF | Synthonix | 171860-66-5 | MFCD00671990 | 202.400 | C4H9BrZn | 0.000 | [Br-].CCC(C)[Zn+] | 25ml | 627353532

Pricing & Availability

3,779

TARGETMOL CHEMICALS INC ALPHA-MSH 5MG

Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. (alpha)-MSH (MSH amide) is amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase. purity: 100%

Pricing & Availability

3,780

eMolecules 405556-97-0 | 2-Chloro-3-fluoro-5-(tributylstannyl)pyridine | Synthonix - Stock | MFCD12827556 | 420.580 | C17H29ClFNSn | 97.000 | CCCC[Sn](CCCC)(CCCC)c1cnc(Cl)c(F)c1 | 1g | 525913608

2-Chloro-3-fluoro-5-(tributylstannyl)pyridine | Synthonix - Stock | 405556-97-0 | MFCD12827556 | 420.580 | C17H29ClFNSn | 97.000 | CCCC[Sn](CCCC)(CCCC)c1cnc(Cl)c(F)c1 | 1g | 525913608

Pricing & Availability

Naphthalenes

Filtered Search Results

Narrow Results

Apexbio Technology LLC Naphthol AS-MX phosphate 1596-56-1 100mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

AdipoGen Naphthol AS-TR phosphate 2Na Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

AdipoGen p-Toluenesulfinic acid Na Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

AdipoGen N N-Bisphosphonomethylglycin Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Fedratinib (hydrochloride hydrate) | 1374744-69-0 | 99.9% | 615.62 | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2-Oxa-5-azabicyclo[2.2.1]heptane, 5-[2-[(8aR)-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl]-6-[6-(4-methoxy-3-pyri | 2769715-68-4 | 99.3% | 592.69 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Linagliptin (BI-1356) 668270-12-0 10mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

TARGETMOL CHEMICALS INC ALPHA-MSH 5MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More