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Filtered Search Results
Medchemexpress LLC BI-4020 | 2664214-60-0 | 99.3% | 10 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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BI-4020 is a fourth-generation, orally active, and non-covalent EGFR tyrosine kinase inhibitor. It inhibits the triple mutant EGFR del19 T790M C797S variant (IC50=0.2 nM in BaF3 cell lines), the double mutant EGFR del19 T790M, and primary mutant EGFR del19 (IC50=1 nM). It also shows activity against EGFR wt (IC50=190 nM). This product demonstrates high kinome selectivity and good DMPK properties and is for research use only.
- Fourth-generation, orally active, and non-covalent EGFR tyrosine kinase inhibitor
- Inhibits triple mutant EGFR del19 T790M C797S variant (IC50=0.2 nM)
- Inhibits double mutant EGFR del19 T790M and primary mutant EGFR del19 (IC50=1 nM)
- Shows activity against EGFR wt (IC50=190 nM)
- Demonstrates high kinome selectivity and good DMPK properties
- Leads to tumor regressions in human PC-9 triple mutant NSCLC xenograft model in mice
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![eMolecules (2-Phenanthryl)zinc bromide, 0.25 M in THF | Synthonix |322.510 | C14H9BrZn | 0.000 | [Br-].[Zn+]c1ccc2c(ccc3ccccc23)c1 | 50ml | 818572034](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502694337.jpg-250.jpg)
eMolecules (2-Phenanthryl)zinc bromide, 0.25 M in THF | Synthonix |322.510 | C14H9BrZn | 0.000 | [Br-].[Zn+]c1ccc2c(ccc3ccccc23)c1 | 50ml | 818572034
(2-Phenanthryl)zinc bromide, 0.25 M in THF | Synthonix |322.510 | C14H9BrZn | 0.000 | [Br-].[Zn+]c1ccc2c(ccc3ccccc23)c1 | 50ml | 818572034
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eMolecules Synthonix 5-Bromo-2-thienylzinc bromide 0.50 M in THF 50ml 532652648 B73258 151073-94-8 MFCD00671986 307.310 C4H2Br2SZn
Synthonix 5-Bromo-2-thienylzinc bromide 0.50 M in THF 50ml 532652648 B73258 151073-94-8 MFCD00671986 307.310 C4H2Br2SZn
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Medchemexpress LLC Butenafine Hydrochloride | 101827-46-7 | 99.9% | 353.93 | 5 G
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Butenafine Hydrochloride | 101827-46-7 | 99.9% | 353.93 | 5 G
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(CCCC)c1nc(C)cs1 | 1g | 525920531](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696697.jpg-250.jpg)
eMolecules 251635-59-3 | 4-Methyl-2-(tributylstannyl)thiazole | Synthonix - Stock | MFCD09025808 | 388.200 | C16H31NSSn | 95.000 | CCCC[Sn](CCCC)(CCCC)c1nc(C)cs1 | 1g | 525920531
4-Methyl-2-(tributylstannyl)thiazole | Synthonix - Stock | 251635-59-3 | MFCD09025808 | 388.200 | C16H31NSSn | 95.000 | CCCC[Sn](CCCC)(CCCC)c1nc(C)cs1 | 1g | 525920531
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![eMolecules 4-Benzyloxybutylzinc bromide, 0.50 M in THF | Synthonix |308.520 | C11H15BrOZn | 0.000 | [Br-].[Zn+]CCCCOCc1ccccc1 | 25ml | 804019712](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502694509.jpg-250.jpg)
eMolecules 4-Benzyloxybutylzinc bromide, 0.50 M in THF | Synthonix |308.520 | C11H15BrOZn | 0.000 | [Br-].[Zn+]CCCCOCc1ccccc1 | 25ml | 804019712
4-Benzyloxybutylzinc bromide, 0.50 M in THF | Synthonix |308.520 | C11H15BrOZn | 0.000 | [Br-].[Zn+]CCCCOCc1ccccc1 | 25ml | 804019712
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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![eMolecules 349552-22-3 | 2,5-Dimethylbenzylmagnesium chloride, 0.25 M in 2-MeTHF | Synthonix178.940 | C9H11ClMg | 0.000 | [Cl-].Cc1ccc(C)c(C[Mg+])c1 | 25ml | 627353587](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502695379.jpg-250.jpg)
eMolecules 349552-22-3 | 2,5-Dimethylbenzylmagnesium chloride, 0.25 M in 2-MeTHF | Synthonix178.940 | C9H11ClMg | 0.000 | [Cl-].Cc1ccc(C)c(C[Mg+])c1 | 25ml | 627353587
2,5-Dimethylbenzylmagnesium chloride, 0.25 M in 2-MeTHF | Synthonix | 349552-22-3178.940 | C9H11ClMg | 0.000 | [Cl-].Cc1ccc(C)c(C[Mg+])c1 | 25ml | 627353587
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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![eMolecules 124434-66-8 | 3-(1,3-Dioxolan-2-yl)phenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock253.378 | C9H9BrMgO2 | 97.000 | [Br-].[Mg+]c1cccc(c1)C1OCCO1 | 50ml | 437237147](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502697662.jpg-250.jpg)
eMolecules 124434-66-8 | 3-(1,3-Dioxolan-2-yl)phenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock253.378 | C9H9BrMgO2 | 97.000 | [Br-].[Mg+]c1cccc(c1)C1OCCO1 | 50ml | 437237147
3-(1,3-Dioxolan-2-yl)phenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 124434-66-8253.378 | C9H9BrMgO2 | 97.000 | [Br-].[Mg+]c1cccc(c1)C1OCCO1 | 50ml | 437237147
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![eMolecules 131379-40-3 | 2-(Ethoxycarbonyl)phenylzinc bromide, 0.50 M in THF | Synthonix | MFCD01863743 | 294.450 | C9H9BrO2Zn | 0.000 | [Br-].CCOC(=O)c1ccccc1[Zn+] | 25ml | 627353626](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502695342.jpg-250.jpg)
eMolecules 131379-40-3 | 2-(Ethoxycarbonyl)phenylzinc bromide, 0.50 M in THF | Synthonix | MFCD01863743 | 294.450 | C9H9BrO2Zn | 0.000 | [Br-].CCOC(=O)c1ccccc1[Zn+] | 25ml | 627353626
2-(Ethoxycarbonyl)phenylzinc bromide, 0.50 M in THF | Synthonix | 131379-40-3 | MFCD01863743 | 294.450 | C9H9BrO2Zn | 0.000 | [Br-].CCOC(=O)c1ccccc1[Zn+] | 25ml | 627353626
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![eMolecules 312692-98-1 | 3,5-Dimethylphenylzinc iodide, 0.50 M in THF | Synthonix297.440 | C8H9IZn | 0.000 | [I-].Cc1cc(C)cc([Zn+])c1 | 50ml | 532652790](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696198.jpg-250.jpg)
eMolecules 312692-98-1 | 3,5-Dimethylphenylzinc iodide, 0.50 M in THF | Synthonix297.440 | C8H9IZn | 0.000 | [I-].Cc1cc(C)cc([Zn+])c1 | 50ml | 532652790
3,5-Dimethylphenylzinc iodide, 0.50 M in THF | Synthonix | 312692-98-1297.440 | C8H9IZn | 0.000 | [I-].Cc1cc(C)cc([Zn+])c1 | 50ml | 532652790
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(CCCC)c1ccnnc1 | 1g | 525923757](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696604.jpg-250.jpg)
eMolecules 194865-89-9 | 4-(Tributylstannyl)pyridazine | Synthonix - Stock | MFCD07787369 | 369.140 | C16H30N2Sn | 95.000 | CCCC[Sn](CCCC)(CCCC)c1ccnnc1 | 1g | 525923757
4-(Tributylstannyl)pyridazine | Synthonix - Stock | 194865-89-9 | MFCD07787369 | 369.140 | C16H30N2Sn | 95.000 | CCCC[Sn](CCCC)(CCCC)c1ccnnc1 | 1g | 525923757
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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![eMolecules 872-26-4 | 1-Hexadecylmagnesium bromide, 0.50 M in THF | Synthonix329.649 | C16H33BrMg | 90.000 | [Br-].CCCCCCCCCCCCCCCC[Mg+] | 25ml | 702445921](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502694985.jpg-250.jpg)
eMolecules 872-26-4 | 1-Hexadecylmagnesium bromide, 0.50 M in THF | Synthonix329.649 | C16H33BrMg | 90.000 | [Br-].CCCCCCCCCCCCCCCC[Mg+] | 25ml | 702445921
1-Hexadecylmagnesium bromide, 0.50 M in THF | Synthonix | 872-26-4329.649 | C16H33BrMg | 90.000 | [Br-].CCCCCCCCCCCCCCCC[Mg+] | 25ml | 702445921
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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![eMolecules 1-Methylpiperidin-4-ylzinc chloride 0.32M in THF | Synthonix - Stock |199.000 | C6H12ClNZn | 95.000 | [Cl-].CN1CCC([Zn+])CC1 | 50ml | 505099750](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502697252.jpg-250.jpg)
eMolecules 1-Methylpiperidin-4-ylzinc chloride 0.32M in THF | Synthonix - Stock |199.000 | C6H12ClNZn | 95.000 | [Cl-].CN1CCC([Zn+])CC1 | 50ml | 505099750
1-Methylpiperidin-4-ylzinc chloride 0.32M in THF | Synthonix - Stock |199.000 | C6H12ClNZn | 95.000 | [Cl-].CN1CCC([Zn+])CC1 | 50ml | 505099750
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![eMolecules 307496-32-8 | 2,5-Difluorobenzylzinc bromide, 0.50 M in THF | Synthonix | MFCD01311422 | 272.400 | C7H5BrF2Zn | 0.000 | [Br-].Fc1ccc(F)c(C[Zn+])c1 | 50ml | 532652758](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696230.jpg-250.jpg)
eMolecules 307496-32-8 | 2,5-Difluorobenzylzinc bromide, 0.50 M in THF | Synthonix | MFCD01311422 | 272.400 | C7H5BrF2Zn | 0.000 | [Br-].Fc1ccc(F)c(C[Zn+])c1 | 50ml | 532652758
2,5-Difluorobenzylzinc bromide, 0.50 M in THF | Synthonix | 307496-32-8 | MFCD01311422 | 272.400 | C7H5BrF2Zn | 0.000 | [Br-].Fc1ccc(F)c(C[Zn+])c1 | 50ml | 532652758
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Rolapitant (hydrochloride hydrate) | 914462-92-3 | 98.4% | 554.95 | 25 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Rolapitant (hydrochloride hydrate) | 914462-92-3 | 98.4% | 554.95 | 25 MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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