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Filtered Search Results
eMolecules 160727-03-7 | 2,4,5-Trimethylphenylmagnesium bromide, 0.5M in THF | Synthonix - Stock | MFCD02260239 | 223.396 | C9H11BrMg | 0.000 | [Br-].Cc1cc(C)c([Mg+])cc1C | 50ml | 437237436
2,4,5-Trimethylphenylmagnesium bromide, 0.5M in THF | Synthonix - Stock | 160727-03-7 | MFCD02260239 | 223.396 | C9H11BrMg | 0.000 | [Br-].Cc1cc(C)c([Mg+])cc1C | 50ml | 437237436
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 124397-96-2 | Hexylzinc bromide, 0.50 M in THF | Synthonix | MFCD00671999 | 230.450 | C6H13BrZn | 0.000 | [Br-].CCCCCC[Zn+] | 50ml | 532652865
Hexylzinc bromide, 0.50 M in THF | Synthonix | 124397-96-2 | MFCD00671999 | 230.450 | C6H13BrZn | 0.000 | [Br-].CCCCCC[Zn+] | 50ml | 532652865
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Medchemexpress LLC Mocravimod hydrochloride | 509088-69-1 | 99.99% | 480.45 | 25 MG
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Mocravimod hydrochloride is an orally active sphingosine-1-phosphate receptor (S1PR) modulator that blocks the signal T cells need to egress from lymph nodes and other lymphoid organs. It preferentially binds to S1PR1 and can be used for the study of acute myelogenous leukemia, diabetes, and Myocardial Ischemia-Reperfusion Injury (MIRI).
- Blocks T cell egress from lymph nodes
- Preferentially binds to S1PR1
- Lowers reactive oxygen species (ROS) concentration
- Prevents mitochondrial permeability transition pore opening
- Boosts mitochondrial membrane potential (MMP)
- Increases phosphorylation of AKT, EKR, GSK-3β, JAK2, and STAT3
- Retains T cell effector function
- Suitable for studying acute myelogenous leukemia, diabetes, and Myocardial Ischemia-Reperfusion Injury (MIRI)
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eMolecules 312693-04-2 | 4-Ethylphenylzinc iodide, 0.50 M in THF | Synthonix297.440 | C8H9IZn | 0.000 | [I-].CCc1ccc([Zn+])cc1 | 50ml | 532652821
4-Ethylphenylzinc iodide, 0.50 M in THF | Synthonix | 312693-04-2297.440 | C8H9IZn | 0.000 | [I-].CCc1ccc([Zn+])cc1 | 50ml | 532652821
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eMolecules 105494-69-7 | 1-Methyl-2-(tributylstannyl)imidazole | Synthonix - Stock | MFCD01319030 | 371.156 | C16H32N2Sn | 97.000 | CCCC[Sn](CCCC)(CCCC)c1nccn1C | 500mg | 525920331
1-Methyl-2-(tributylstannyl)imidazole | Synthonix - Stock | 105494-69-7 | MFCD01319030 | 371.156 | C16H32N2Sn | 97.000 | CCCC[Sn](CCCC)(CCCC)c1nccn1C | 500mg | 525920331
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eMolecules 1341189-34-1 | (6-Methoxypyridin-3-yl)magnesium bromide, 0.25 M in 2-MeTHF | Synthonix - Stock | MFCD18253597 | 212.329 | C6H6BrMgNO | 0.000 | [Br-].COc1ccc([Mg+])cn1 | 100ml | 507877502
(6-Methoxypyridin-3-yl)magnesium bromide, 0.25 M in 2-MeTHF | Synthonix - Stock | 1341189-34-1 | MFCD18253597 | 212.329 | C6H6BrMgNO | 0.000 | [Br-].COc1ccc([Mg+])cn1 | 100ml | 507877502
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Medchemexpress LLC BI 2536 | 755038-02-9 | 99.92% | C28H39N7O3 | 1 ML
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BI 2536 is a dual inhibitor targeting PLK1 and BRD4, with IC50 values of 0.83 nM and 25 nM respectively. It is known to suppress IFNB (encoding IFN-β) gene transcription and induces mitotic arrest and apoptosis in various human cancer cell lines. This compound has been shown to inhibit tumor growth in vivo and exhibits good blood-brain barrier permeability, causing mitotic arrest in glioblastoma-derived neural stem cells but not normal neural stem cells.
- Inhibits PLK1 and BRD4.
- Suppresses IFNB gene transcription.
- Induces mitotic arrest and apoptosis in cancer cells.
- Inhibits tumor growth in vivo.
- Exhibits blood-brain barrier permeability.
- Used in Western blot, immunofluorescence, and growth inhibition assays.
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Aobchem AOBCHEM
5000919798 1- 6- 1-METHYLETHOXY -2-NAPHTH
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Aobchem 2 2-Difluoro-1-(naphthalen-1-yl)ethanone | ≥97% | CAS 715-80-0 | C12H8F2O | 1g
2 2-Difluoro-1-(naphthalen-1-yl)ethanone | ≥97% | CAS 715-80-0 | C12H8F2O | 1g
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Aobchem 2 2-Difluoro-1-(naphthalen-1-yl)ethanone | ≥97% | CAS 715-80-0 | C12H8F2O | 250mg
2 2-Difluoro-1-(naphthalen-1-yl)ethanone | ≥97% | CAS 715-80-0 | C12H8F2O | 250mg
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Medchemexpress LLC Naphthol AS-E | 92-78-4 | 98.0% | 297.74 | C17H12ClNO2 | 50 MG
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Naphthol AS-E is a small-molecule, cell-permeable inhibitor of the KIX-KID protein-protein interaction used in biochemical and cell-based research. It binds the KIX domain of CBP and blocks the KIX-KID interaction, making it useful for mechanistic studies of transcriptional regulation.
- Inhibits KIX-KID interaction with IC50 2.26 μM.
- Binds CBP KIX domain (Kd ~8.6 μM).
- High purity: 98.0%.
- Molecular weight: 297.74 Da.
- Soluble in DMSO (~41.67 mg/mL) for in vitro use.
- Storage: powder stable at -20°C (up to 3 years) and 4°C (up to 2 years).
- Available as a 50 MG solid for laboratory research.
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eMolecules 2105938-35-8 | N2,N6-Dicyanopyridine-2,6-bis(carboximidamide) | Synthonix213.204 | C9H7N7 | 95.000 | N=C(NC#N)c1cccc(n1)C(=N)NC#N | 250mg | 722002442
N2,N6-Dicyanopyridine-2,6-bis(carboximidamide) | Synthonix | 2105938-35-8213.204 | C9H7N7 | 95.000 | N=C(NC#N)c1cccc(n1)C(=N)NC#N | 250mg | 722002442
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eMolecules 21450-63-5 | 2-Ethylphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | MFCD02260221 | 209.369 | C8H9BrMg | 0.000 | [Br-].CCc1ccccc1[Mg+] | 500ml | 437237184
2-Ethylphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 21450-63-5 | MFCD02260221 | 209.369 | C8H9BrMg | 0.000 | [Br-].CCc1ccccc1[Mg+] | 500ml | 437237184
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eMolecules 18653-75-3 | 2-(Pyridyl-2-yl)imidazole | ChemScene | MFCD05863221 | 145.165 | C8H7N3 | 97.000 | c1c[nH]c(n1)-c1ccccn1 | 5g | 536853473
2-(Pyridyl-2-yl)imidazole | ChemScene | 18653-75-3 | MFCD05863221 | 145.165 | C8H7N3 | 97.000 | c1c[nH]c(n1)-c1ccccn1 | 5g | 536853473
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules (2-Acetoxyphenyl)zinc iodide, 0.50 M in THF | SynthonixMFCD03840885 | 327.430 | C8H7IO2Zn | 0.000 | [I-].CC(=O)Oc1ccccc1[Zn+] | 25ml | 811234624
(2-Acetoxyphenyl)zinc iodide, 0.50 M in THF | SynthonixMFCD03840885 | 327.430 | C8H7IO2Zn | 0.000 | [I-].CC(=O)Oc1ccccc1[Zn+] | 25ml | 811234624
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