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Filtered Search Results
AdipoGen 3 4-Dihydroxy-L-phenylalanine
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Chemical. CAS 59-92-7. Formula C9H11NO4. MW 197.19. Synthetic. Metabolic precursor of the neurotransmitters dopamine, norepinephrine noradrenaline, and epinephrine adrenaline, which are collectively known as catecholamines. This amino acid is produced from L-tyrosine by tyrosine hydroxylase and metabolized by catechol-O-methyl transferase COMT. L-DOPA is capable of crossing the blood brain barrier where it is converted to dopamine. Formulations containing L-DOPA have been used to increase dopamine concentrations in the brain as a treatment for Parkinson’s disease and stroke recovery. Mediates neurotrophic factor release by the brain and CNS. Used for the treatment of Parkinson’s disease and dopamine-responsive dystonia. In addition it is used, as a cell adhesion molecule in serum-free cultures of anchorage-dependent mammalian cells, to prevent surfaces from fouling by bonding antifouling polymers to a susceptible substrate or to stain melanocytes.
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eMolecules 2378318-41-1 | 3-(Benzyloxy)propylzinc bromide, 0.5 M in THF | Synthonix294.500 | C10H13BrOZn | 0.000 | [Br-].[Zn+]CCCOCc1ccccc1 | 25ml | 771375794
3-(Benzyloxy)propylzinc bromide, 0.5 M in THF | Synthonix | 2378318-41-1294.500 | C10H13BrOZn | 0.000 | [Br-].[Zn+]CCCOCc1ccccc1 | 25ml | 771375794
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eMolecules 134640-85-0 | 2,3-Dimethylphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | MFCD01311494 | 209.369 | C8H9BrMg | 0.000 | [Br-].Cc1cccc([Mg+])c1C | 100ml | 437237098
2,3-Dimethylphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 134640-85-0 | MFCD01311494 | 209.369 | C8H9BrMg | 0.000 | [Br-].Cc1cccc([Mg+])c1C | 100ml | 437237098
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eMolecules 21473-02-9 | 4-Phenoxyphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock273.412 | C12H9BrMgO | 97.000 | [Br-].[Mg+]c1ccc(Oc2ccccc2)cc1 | 500ml | 437237425
4-Phenoxyphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 21473-02-9273.412 | C12H9BrMgO | 97.000 | [Br-].[Mg+]c1ccc(Oc2ccccc2)cc1 | 500ml | 437237425
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Medchemexpress LLC Paroxetine hydrochloride hemihydrate | 110429-35-1 | 100.0% | 1 ML
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Paroxetine hydrochloride hemihydrate | 110429-35-1 | 100.0% | 1 ML
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eMolecules Synthonix Hex-5-enylmagnesium bromide 0.5M in THF 25ml 627353658 H5025 30043-41-5 MFCD22684728 187.363 C6H11BrMg
Synthonix Hex-5-enylmagnesium bromide 0.5M in THF 25ml 627353658 H5025 30043-41-5 MFCD22684728 187.363 C6H11BrMg
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Medchemexpress LLC Bi-3812 | 2166387-64-8 | 99.3% | 558.03 | 1 ML
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BI-3812 is identified as a chemical probe and a highly efficient BCL6 inhibitor that suppresses the BTB domain of BCL6 with an IC50 of ≤ 3 nM, demonstrating antitumor activity.
- Highly efficient BCL6 inhibitor.
- Capable of suppressing the BTB domain of BCL6.
- Exhibits antitumor activity.
- IC50 value of ≤ 3 nM for BCL6 BTB.
- IC50 of 40 nM for cellular BCL6.
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Medchemexpress LLC Zelavespib hydrochloride | 2095432-24-7 | 99.25% | 548.83 | 25 MG
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Zelavespib hydrochloride is a potent Hsp90 inhibitor primarily used for research. It demonstrates significant activity against various tumor cells, inducing apoptosis and inhibiting growth.
- Potent Hsp90 inhibitor with an IC50 of 51 nM in MDA-MB-468 cells.
- Inhibits growth of multiple tumor cell lines.
- Induces significant apoptosis in triple-negative breast cancers (TNBCs).
- Downregulates oncoproteins involved in the invasive potential of TNBCs.
- Cytotoxic to CLL cells with minimal effects on PBMC or resting B cells.
- Reduces CLL viability by inducing mitochondrial apoptosis.
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eMolecules 1142219-89-3 | 4-Bromo-3-methylphenylzinc iodide, 0.50 M in THF | Synthonix362.310 | C7H6BrIZn | 0.000 | [I-].Cc1cc([Zn+])ccc1Br | 25ml | 627353504
4-Bromo-3-methylphenylzinc iodide, 0.50 M in THF | Synthonix | 1142219-89-3362.310 | C7H6BrIZn | 0.000 | [I-].Cc1cc([Zn+])ccc1Br | 25ml | 627353504
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eMolecules 535961-78-5 | 2-Fluoro-6-methylbenzoyl chloride | Combi-Blocks | MFCD06660278 | 172.580 | C8H6ClFO | 98.000 | Cc1cccc(F)c1C(Cl)=O | 1g | 267180321
2-Fluoro-6-methylbenzoyl chloride | Combi-Blocks | 535961-78-5 | MFCD06660278 | 172.580 | C8H6ClFO | 98.000 | Cc1cccc(F)c1C(Cl)=O | 1g | 267180321
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eMolecules AstaTech (S)-N-BOC-2-AMINOCYCLOHEXANONE 5g 411875463 AC2588 95.000 145106-47-4 MFCD09838825 213.277 C11H19NO3
AstaTech (S)-N-BOC-2-AMINOCYCLOHEXANONE 5g 411875463 AC2588 95.000 145106-47-4 MFCD09838825 213.277 C11H19NO3
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AdipoGen Tetrafluoro-IBA
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Chemical. CAS 954373-94-5. Formula C7HF4IO3. MW 335.98. Synthetic Hypervalent iodine reagents. Convenient substitute of o-Iodosobenzoic acid IBA as an oxidant. Can be used for installations of alpha/beta-unsaturation to carbonyl compounds, oxidations and cyclizations by single-electron transfer processes. Promotes faster reactions than IBA with better solubility in common organic solvents. An attractive feature is the ability to directly measure reactivity by 19F NMR spectroscopy without the use of deuterated solvents.
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eMolecules 126403-67-6 | Isobutylzinc bromide, 0.50 M in THF | Synthonix202.400 | C4H9BrZn | 0.000 | [Br-].CC(C)C[Zn+] | 50ml | 627353673
Isobutylzinc bromide, 0.50 M in THF | Synthonix | 126403-67-6202.400 | C4H9BrZn | 0.000 | [Br-].CC(C)C[Zn+] | 50ml | 627353673
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Apexbio Technology LLC Naphthol AS-MX phosphate 1596-56-1 100mg
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Naphthol AS-MX phosphate (CAS 1596-56-1) is a small molecule inhibitor that disrupts the interaction between cAMP response element-binding protein (CREB) and CREB-binding protein (CBP) key components of a transcription factor complex In lung cancer cells it demonstrates antiproliferative effects as evidenced by an IC50 of 3 701 mol/L and inhibits both colony formation and anchorage-independent growth Naphthol AS-MX phosphate is utilized in studies investigating KRAS-mutant lung cancers particularly in the context of chemoresistance and poor prognosis
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AdipoGen Naphthol AS-TR phosphate 2Na
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Chemical. CAS 4264-93-1. Formula C18H13CINNa2O5P. MW BD9837. Naphthol AS-TR Phosphate is a fluorogenic substrate for acid and alkaline phosphatases. Naphthol AS-TR Phosphate is converted to naphthol AS-TR displaying excitation/emission spectra of 388/512nm. The fluorescence is a quantitative marker of acid and alkaline phosphatase activity. Acid and alkaline phosphatases are often used as clinical markers of disease, since the concentration of human acid and alkaline phosphatases undergo pronounced changes in particular diseases, resulting in unusually high or low concentrations. It is a histochemical substrate commonly used in conjunction with diazonium salts to form a specific azo dye for immunohistology, immunoblotting and dot blot applications. Naphthol AS-TR Phosphate is a cyclic-AMP response element-binding protein CREB-CREB binding protein CBP transcription factor complex inhibitor and a potential therapeutic agent for lung cancer.
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