Phenanthrenes and derivatives
Medchemexpress LLC Hypericin (standard) | 548-04-9 | 504.44 | 25 MG
Hypericin (Standard) is the analytical standard of Hypericin, a naturally occurring substance found in Hyperlcurn perforatum L. This product is intended for research and analytical applications, and is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Inhibitor of PKC, MAO, dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP
- Shows antitumor, antiviral, and antidepressive activities
- Can induce apoptosis
Medchemexpress LLC Hypericin | 548-04-9 | 98.0% | 504.44 g/mol | C30H16O8 | 10 MG
Hypericin is a photosensitive natural compound (C30H16O8) used in biochemical research as an inhibitor of protein kinase C (PKC) and monoamine oxidase (MAO). It is applied in studies of apoptosis, phototoxicity, antiviral activity, and antidepressant mechanisms, and is supplied as a solid or solution for in vitro experiments.
- Used as a PKC and MAO inhibitor in biochemical research.
- CAS number 548-04-9; molecular weight 504.44 g/mol.
- Purity typically 98.0% and appears as a brown to black solid.
- Soluble in DMSO (≈250 mg/mL with warming and ultrasonication).
- Storage: powder at -20°C (up to 3 years) or 4°C (up to 2 years); solutions -80°C (up to 6 months).
- Available in small research quantities such as 10 MG and solution formats.
Selleck Chemical LLC Hypericin S3273-5mg
Hypericin (Hyp HY) is a naturally occurring substance found in the common St John s Wort (Hypericum species) with antidepressive antineoplastic and antiviral (human immunodeficiency and hepatitis C virus) activities Hypericin has inhibitory effects on MAO (monoaminoxidase) PKC (protein kinase C) dopamine-beta-hydroxylase reverse transcriptase telomerase and CYP (cytochrome P450)
Medchemexpress LLC 2H-1-Benzopyran-7-ol, 3,4-dihydro-3-(4-hydroxyphenyl)-4-(4-methoxyphenyl)-, (3R,4S)-rel- | 1213777-80-0 | 723112 | 99.6% | C22H20O4 | 25 MG
Triphen diol is a phenol diol derivative known for its excellent anticancer activity against pancreatic cancer and cholangiocarcinoma. It induces pancreatic cell apoptosis through both caspase-mediated and caspase-independent mechanisms, and is intended for research use only.
- Inhibits proliferation of pancreatic cells (IC50 values: 8 μM for HPAC and PANC-1; 0.8 μM for MIAPaCa-2).
- Induces caspase-dependent apoptosis in MIAPaCa-2 and PANC-1 cells (60% early-stage, 30% late-stage).
- Reduces Bcl-2 levels in MIAPaCa-2 and HPAC cell lines.
- Significantly inhibits tumor proliferation in male Balb/c nude mice with MIAPaCa2 cells.
- Shows enhanced efficacy when combined with gemcitabine in vivo.
Medchemexpress LLC PROTAC BCR-ABL1 ligand 1 | 2489876-34-6 | 99.17% | 50 MG
PROTAC BCR-ABL1 ligand 1, also known as compound GMB-475, is a PROTAC ligand that allosterically targets the BCR-ABL1 protein. It functions by recruiting the E3 ligase Von Hippel-Lindau, which leads to the ubiquitination and subsequent degradation of BCR-ABL1.
- Allosterically targets the BCR-ABL1 protein.
- Recruits the E3 ligase Von Hippel-Lindau.
- Induces ubiquitination and subsequent degradation of BCR-ABL1.
- Inhibits cell proliferation with IC50 values of 1.11 μM for WT cells, 1.98 μM for T315I cells, and 0.37 μM for G250E cells.
- Induces the degradation of c-ABL1.
- Inhibits downstream signaling through the STAT5 pathway in K562 and Ba/F3 cells.
eMolecules Oakwood Chemical Malonic acid 1kg 537678614 020000 0 000 141-82-2 104 061 C3H4O4
Oakwood Chemical Malonic acid 1kg 537678614 020000 0 000 141-82-2 104 061 C3H4O4
Crescent Chemical Co Inc 6-HYDROXY-CHRYSENE 10 MG
6-Hydroxy-chrysene Polycyc. arom. hydrocarb. (WS) CAS 37515-51-8 Molecular Weight - 244.2873 Storage - RT Catalog Num - DRE-E20990600 chemical
eMolecules 6-Methyl Chrysene | 1705-85-7 | MFCD00215920 | 100mg
Toronto Research Chemicals | 6-Methyl Chrysene | 100mg | 601597882 | M265140 | | 1705-85-7 | MFCD00215920 | 242.321 | C19H14
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![Sigma Aldrich Fine Chemicals Biosciences Benzo[c]chrysene BCR(R), certified reference material | 194-69-4 | MFCD00667762 | 100MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/501759706.PNG-250.jpg)
Sigma Aldrich Fine Chemicals Biosciences Benzo[c]chrysene BCR(R), certified reference material | 194-69-4 | MFCD00667762 | 100MG
Benzo[c]chrysene BCR(R), certified reference material | Mol Wt: 278.35 | 194-69-4 | MFCD00667762 | 100MG
