Phenanthrenes and derivatives
Apexbio Technology LLC Malonic acid 141-82-2 500mg
Malonic acid is a small-molecule dicarboxylic acid It is commonly used to facilitate the cross-linking of polysaccharide molecules such as corn starch and potato starch by forming covalent linkages via its two carboxyl groups Malonic acid acts primarily through condensation or esterification reactions to increase intermolecular connectivity and modulate the mechanical properties of biopolymer matrices Based on these properties malonic acid holds research potential in pharmaceutical excipient formulation drug delivery system development and biomaterial engineering studies
Apexbio Technology LLC ARISTOLOCHIC-ACID-A-20MG
Aristolochic Acid A (CAS No 313-67-7) is a compound primarily explored in the field of toxicology and pharmacology Originating from the Aristolochiaceae family it is known for its role as a potent nephrotoxin and carcinogen making it a subject of interest in studies of renal toxicity and cancer research The compound acts by binding to DNA forming adducts that can lead to mutations particularly affecting pathways related to the cell cycle and apoptosis Its activity is typically observed in the nanomolar to low micromolar range Aristolochic Acid A is often used in vitro with various cell models such as renal epithelial cells and in vivo in animal models to understand its toxic effects and the mechanisms leading to tumorigenesis It is also employed in drug screening processes to identify potential inhibitors that may counter its detrimental effects Experimental concentrations typically depend on the specific research design
Medchemexpress LLC Aristolochic acid B | 475-80-9 | 311.25 | 5 MG
Aristolochic acid B (Aristolochic Acid II) is an orally active major component of aristolochic acid (AA). It can be isolated from plants of the genus Aristolochica. Aristolochic acid B forms DNA adducts, is mutagenic, and exhibits a greater carcinogenic risk in vivo than Aristolochic acid I.
- Target: DNA alkylator/crosslinker
- Research area: Cancer
- Mechanism: Forms DNA adducts and is mutagenic
- Carcinogenic risk: Exhibits greater carcinogenic risk in vivo than Aristolochic acid I
- Appearance: Solid
- Melting/freezing point: 270-272°C
eMolecules 475-80-9 | Medchem Express | Aristolochic acid B | 1mg | 527573755 | HY-N0511 | MFCD01708574 | 311.249 | C16H9NO6
Ambeed | 2-Chloro-5-methoxypyrimidin-4-amine | 250mg | 525198004 | A367660 | 99979-77-8 | MFCD17169913 | 159.570 | C5H6ClN3O
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Medchemexpress LLC Prazosin (hydrochloride) | 19237-84-4 | 99.9% | 200 MG
Prazosin hydrochloride is a well-tolerated, CNS-active α1-adrenergic receptor antagonist. It is utilized in research for high blood pressure and alcohol use disorders. The compound effectively inhibits Norepinephrine (NE)-stimulated 45Ca efflux with an IC50 of 0.15 nM and also inhibits organic cation transporters OCT-1 and OCT-3 with IC50s of 1.8 and 13 μM, respectively.
- Acts as a CNS-active α1-adrenergic receptor antagonist
- Used in research for high blood pressure
- Used in research for alcohol use disorders
- Potently inhibits Norepinephrine (NE)-stimulated 45Ca efflux
- Inhibits organic cation transporters OCT-1 and OCT-3
Medchemexpress LLC Amorolfine hydrochloride | 78613-38-4 | 99.6% | 200 MG
Amorolfine hydrochloride (Standard) is an analytical standard and a potent anti-fungal agent that inhibits ergosterol biosynthesis. It is intended for research and analytical applications, with potential for the research of Neoscytalidium dimidiatum onychomycosis.
- Inhibits ergosterol biosynthesis
- Possesses fungistatic and fungicidal activity
- Effective against dermatophyte fungi, filamentous fungi, pathogenic yeasts, dimorphic fungi, and dematiaceous fungi
- Used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS
Sigma Aldrich Fine Chemicals Biosciences Aristolochic acid I European Pharmacopoeia (EP) Reference Standard | 313-67-7 | MFCD00004996 |
Aristolochic acid I European Pharmacopoeia (EP) Reference Standard | Mol Wt: 341.27 | 313-67-7 | MFCD00004996 |
![Sigma Aldrich Fine Chemicals Biosciences Benzo[a]pyrene | 50-32-8 | MFCD00003602 | 100mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/501848401.jpg-250.jpg)
Sigma Aldrich Fine Chemicals Biosciences Benzo[a]pyrene | 50-32-8 | MFCD00003602 | 100mg
Benzo[a]pyrene | Purity: 96% | Mol Wt: 252.31 | 50-32-8 | MFCD00003602 | 100mg
Cayman Chemical ArIstolochIc AcId 25mg
A PLA2 inhibitor (IC50 = 40 µM in human neutrophils); inhibits human synovial fluid PLA2-induced edema in a dose-dependent manner in vivo; inhibits hemolytic activity of the PLA2 enzymes TFV PL-X, TFV PL-Ia, and TFV PL-Ib from T. flavoviridis venom (IC50s = 4.6, 4.0, and 3.9 µM, respectively); enhances the edema-inducing activity of TFV PL-Ia and TFV PL-Ib; associated with progressive interstitial fibrosing nephropathy and upper urinary tract urothelial carcinomas
TARGETMOL CHEMICALS INC Aristolochic acid A 100MG
Also available in 1 mL, 10 mg, 25 mg, 50 mg, 500 mg and bulk. Please contact Fisher for quotes. Aristolochic acid A (TR 1736) is a compound of mutagenic, carcinogenic, and nephrotoxic compounds commonly found in the Birthwort (Aristolochiaceae) family of plants. Purity 99.97%
Electron Microscopy Sciences Rosin Alcoholic Stock Solution 250 ML
Used in Wolbach's Giemsa Method, Wolbach, Todd, and Palfrey (1922) for the staining of : nuclei, collagen, riskettsia and bacteria. See references Wolbach, S.B., Todd, J.L., and Paltrey, F.W., The Etiology of Pathology Typhus, Harvard University Press, Cambridge, MA, p. 13-14, c. 1922 and Luna, L.G., (ed). Manual of Histologic Staining Methods od the AFIP, 3rd edition. McGraw-Hill, NY, p. 119, c. 1968.
Medchemexpress LLC Dasatinib hydrochloride | 854001-07-3 | 99.3% | 524.5 g·mol⁻¹ | C22H27Cl2N7O2S | 200 MG
Dasatinib hydrochloride is a research-grade, ATP-competitive dual Src and Bcr-Abl kinase inhibitor supplied as the hydrochloride salt. It exhibits subnanomolar to low-nanomolar activity against its targets and is intended for laboratory and preclinical research applications; supplied at high purity for analytical use.
- High purity: 99.31%.
- Potent dual Src and Bcr-Abl inhibition at subnanomolar to low-nanomolar concentrations.
- Supplied as the hydrochloride salt in solid form for research use.
- Suitable for research and analytical applications; not for human consumption.
- Available in multiple pack sizes, including 200 MG.