Phenanthrenes and derivatives
Selleck Chemical LLC Malonic acid S3029-100mg
Malonic acid (MOA) one of the major dicarboxylic acids (DCAs) in aerosols has been identified experimentally and computationally to be a strong acid Malonic acid (MOA) acts as a mediate bridge for the formation of pure SA-A-based clusters
Chem-Impex International, Inc. 9,10-Phenanthrenequinone | MFCD00001163 | 100G
9,10-Phenanthrenequinone, MFCD00001163, 100G
Accela Chembio Inc Triphenylene | 25g | 217-59-4 | MFCD00001108 | 97+% | Shelf Life: 900 Days | Light Sensitive
Triphenylene | 25g | 217-59-4 | MFCD00001108 | 97+% | Shelf Life: 900 Days | Light Sensitive
Medchemexpress LLC Amorolfine hydrochloride | 78613-38-4 | 99.6% | 200 MG
Amorolfine hydrochloride (Standard) is an analytical standard and a potent anti-fungal agent that inhibits ergosterol biosynthesis. It is intended for research and analytical applications, with potential for the research of Neoscytalidium dimidiatum onychomycosis.
- Inhibits ergosterol biosynthesis
- Possesses fungistatic and fungicidal activity
- Effective against dermatophyte fungi, filamentous fungi, pathogenic yeasts, dimorphic fungi, and dematiaceous fungi
- Used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS
Medchemexpress LLC 2H-1-Benzopyran-7-ol, 3,4-dihydro-3-(4-hydroxyphenyl)-4-(4-methoxyphenyl)-, (3R,4S)-rel- | 1213777-80-0 | 723112 | 99.6% | C22H20O4 | 25 MG
Triphen diol is a phenol diol derivative known for its excellent anticancer activity against pancreatic cancer and cholangiocarcinoma. It induces pancreatic cell apoptosis through both caspase-mediated and caspase-independent mechanisms, and is intended for research use only.
- Inhibits proliferation of pancreatic cells (IC50 values: 8 μM for HPAC and PANC-1; 0.8 μM for MIAPaCa-2).
- Induces caspase-dependent apoptosis in MIAPaCa-2 and PANC-1 cells (60% early-stage, 30% late-stage).
- Reduces Bcl-2 levels in MIAPaCa-2 and HPAC cell lines.
- Significantly inhibits tumor proliferation in male Balb/c nude mice with MIAPaCa2 cells.
- Shows enhanced efficacy when combined with gemcitabine in vivo.
Electron Microscopy Sciences Rosin Alcoholic Stock Solution 250 ML
Used in Wolbach's Giemsa Method, Wolbach, Todd, and Palfrey (1922) for the staining of : nuclei, collagen, riskettsia and bacteria. See references Wolbach, S.B., Todd, J.L., and Paltrey, F.W., The Etiology of Pathology Typhus, Harvard University Press, Cambridge, MA, p. 13-14, c. 1922 and Luna, L.G., (ed). Manual of Histologic Staining Methods od the AFIP, 3rd edition. McGraw-Hill, NY, p. 119, c. 1968.
eMolecules Key Organics/BIONET Malonic acid 50mg 564178360 STR00614 95 000 141-82-2 104 061 C3H4O4
Key Organics/BIONET Malonic acid 50mg 564178360 STR00614 95 000 141-82-2 104 061 C3H4O4
Medchemexpress LLC Aristolochic acid A | 313-67-7 | MFCD00004996 | 99.9% | 10 MG
Aristolochic acid A is a nitrophenanthrene carboxylic acid supplied as a high-purity research reagent for biochemical and cell-based studies. It is commonly used to investigate NF-κB and AP-1 signaling pathways and for mechanistic studies of nephrotoxicity and carcinogenesis.
- High purity (99.9%).
- Molecular formula C17H11NO7; molecular weight 341.27 g/mol.
- Typically supplied as a 10 mg quantity suitable for research use.
- Used in studies of NF-κB and AP-1 inhibition and mechanisms of nephrotoxicity and carcinogenicity.
- Handle as a toxic and carcinogenic compound with appropriate safety precautions.
Medchemexpress LLC Alvespimycin (hydrochloride) | 467214-21-7 | 98.8% | 653.21 | 200 MG
Alvespimycin hydrochloride is a potent inhibitor of Hsp90, binding to Hsp90 with an EC50 of 62 ± 29 nM. It inhibits the growth of human cancer cell lines SKBR3 and SKOV3, which overexpress Hsp90 client protein Her2, leading to down-regulation of Her2 and induction of Hsp70. It also induces dose-dependent apoptosis in chronic lymphocytic leukemia (CLL) cells.
- Potent inhibitor of Hsp90
- Binds to Hsp90 with an EC50 of 62 ± 29 nM
- Inhibits the growth of human cancer cell lines SKBR3 and SKOV3
- Causes down-regulation of Her2
- Induces Hsp70
- Induces dose-dependent apoptosis in chronic lymphocytic leukemia (CLL) cells
- Significant reduction in tumor size in animal models
Cayman Chemical ArIstolochIc AcId C 10mg
An alkaloid; inhibits the growth of LLC-PK1, P388, HT-29, and HL-60 cancer cells (IC50s = 85, 8.8, 17.1, and 40 µM, respectively)