Unsubstituted Phenols
Medchemexpress LLC HY-W009884 100mg Medchemexpress, Acetosyringone CAS:2478-38-8 Purity:>98%
Medchemexpress, HY-W009884 100mg Acetosyringone CAS:2478-38-8 Acetosyringone is a phenolic compound from wounded plant cells, enables virA gene which encodes a membrane-bound kinase to phosphorylate itself and activate the virG gene product, which stimulates the transcription of other vir genes and itself [1] . Acetosyringone enhances efficient Dunaliella transformation of Agrobacterium strains [2] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Theaflavin-3'-gallate | 28543-07-9 | MFCD03427514 | 98.8% | 10 MG
Theaflavin-3'-gallate is a polyphenolic theaflavin monomer derived from black tea, supplied as a research reagent for biochemical and cellular studies. It has reported bioactivities including pro-oxidant effects and inhibition of xanthine oxidase, and is provided with safety documentation for laboratory handling.
- High purity suitable for research use.
- Available as small solid quantities and in DMSO solution for convenience.
- Documented molecular data and CAS identifier for unambiguous identification.
- Suitable for biochemical and cellular assays investigating oxidative stress and related pathways.
- Provided with SDS/COA for safe handling and quality verification.
Medchemexpress LLC Luteolin 5-O-glucoside | 20344-46-1 | 448.38 | 5 MG
Luteolin 5-O-glucoside is a major flavonoid derived from Cirsium maackii with notable anti-inflammatory activity. It is known to inhibit LPS-induced NO production and t-BHP-induced ROS generation. This compound also suppresses the expression of iNOS and COX-2 in macrophages.
- Exhibits anti-inflammatory activity
- Inhibits LPS-induced NO production
- Inhibits t-BHP-induced ROS generation
- Suppresses the expression of iNOS and COX-2 in macrophages
- Effective at non-toxic concentrations in RAW 264.7 cells
Medchemexpress LLC Isovitexin 2"-O-arabinoside | 53382-71-1 | 5 MG
Isovitexin 2''-O-arabinoside is a flavonoid found in plantlets of Avena sativa L. It increases alkaline phosphatase (ALP) activity and promotes BMP-2-induced osteoblast differentiation in C2C12 cells at concentrations from 0-10 μM over 3 days. It is for research use only.
- Flavonoid found in Avena sativa L. plantlets
- Increases alkaline phosphatase (ALP) activity
- Promotes BMP-2-induced osteoblast differentiation
- Targets phosphatase
- Involved in metabolic enzyme/protease pathway
Medchemexpress LLC Syringaresinol diglucoside | 66791-77-3 | 742.72 | 5 MG
Syringaresinol diglucoside is a natural compound found in bamboo leaves.
- Natural compound sourced from bamboo leaves.
- Suitable for research applications.
- Product is a solid, white to off-white in appearance.
Medchemexpress LLC Luteolin 7-diglucuronide | 96400-45-2 | 10 MG
Luteolin 7-diglucuronide is the main flavonoid isolated from *Aloysia triphylla* and *Verbena officinalis*. It presents as a yellow to brown solid and has demonstrated significant biological activities both in vitro and in vivo.
- Inhibits protein tyrosine phosphatase 1B (PTP1B) activity with an IC50 of 2.10 μM.
- Upregulates the phosphorylation of AMPK, inhibiting the activation of hepatic stellate cells.
- Exhibits protective effects against Isoproterenol-induced myocardial injury and fibrosis in mouse models.
- Reduces myocardial necrosis, granulation tissue formation, and inflammatory cell infiltration.
- Inhibits the expression of NADPH oxidase subunits and ECM genes.
Medchemexpress LLC NUCC-390 dihydrochloride | 2749281-71-6 | 98.2% | 468.46 | 100 MG
NUCC-390 dihydrochloride is a novel and selective small-molecule CXCR4 receptor agonist. It induces internalization of CXCR4 receptors and acts in an opposite way to AMD3100. NUCC-390 dihydrochloride promotes nerve recovery of function after neurodegeneration in vivo.
- Novel and selective small-molecule CXCR4 receptor agonist.
- Induces internalization of CXCR4 receptors.
- Acts in an opposite way of AMD3100.
- Promotes nerve recovery of function after neurodegeneration in vivo.
- Produces strong (Ca)i response (at 10 μM).
- Stimulates signaling activity downstream of CXCR4 receptors.
- Boosts axonal growth in cultured cerebellar granule neurons (CGNs) via CXCR4.
- Contributes to the functional and anatomical recovery of the neuromuscular junction (NMJ) following acute nerve terminal damage in vivo.
Medchemexpress LLC 4-O-Methyl honokiol | 68592-15-4 | 280.36 | 50 MG
4-O-Methyl honokiol is a natural neolignan isolated from Magnolia officinalis. It acts as a PPARγ agonist and inhibits NF-κB activity. This compound is utilized in cancer and inflammation research and is for research use only.
- Isolated from Magnolia officinalis
- Acts as a PPARγ agonist
- Inhibits NF-κB activity
- Used for cancer research
- Used for inflammation research
- For research use only
Enzo Life Sciences 10-Hydroxycamptothecin (20mg). CAS: 64439-81-2
A DNA topoisomerase I inhibitor that induces differentiation in HL-60 cells. It induces apoptosis in human breast cancer cell lines MCF-7 and MDA-MB-468. Purity: ≥97%. Solubility: Soluble in DMSO. Long Term Storage: -20°C.
Medchemexpress LLC Tyrphostin AG-825 | 149092-50-2 | MFCD01074971 | 98.0% | 397.47 g·mol⁻¹ | C19H15N3O3S2 | 10 MG
AG-825 (Tyrphostin AG-825) is a selective, ATP-competitive ErbB2 (HER2) tyrosine kinase inhibitor used in cellular and biochemical research to probe ErbB2 signaling and cell proliferation. It exhibits anticancer and anti-inflammatory activity and has been shown to accelerate apoptosis in human neutrophils.
- Selective ErbB2 inhibitor with reported IC50 of 0.35 μM.
- Additional activity against EGFR with IC50 ~19 μM.
- High purity suitable for research, reported at 98.02%.
- Molecular weight 397.47 g·mol⁻¹; formula C19H15N3O3S2.
- Soluble in DMSO (recommended 250 mg/mL with ultrasonic assistance) and formulatable for in vivo use.
- Available in small research pack sizes and larger quantities for expanded studies.
- Stable as powder and in solvent when stored under the recommended conditions.
Medchemexpress LLC Diosmetin-7-O-β-D-glucopyranoside | 20126-59-4 | 462.40 | 5 MG
Diosmetin-7-O-β-D-glucopyranoside | 20126-59-4 | 462.40 | 5 MG
Medchemexpress LLC Schisanhenol | 69363-14-0 | 402.48 | 50 MG
Schisanhenol, an orally active lignan and antioxidant, targets pathways related to oxidative stress and neurodegeneration. It is utilized in research for Alzheimer's disease, atherosclerosis, brain ischemia, and age-related brain deterioration.
- Orally active antioxidant
- Reduces AChE activity
- Increases SIRT1 and PGC-1α expression
- Decreases phosphorylated Tau (Ser 396) levels
- Increases SOD and glutathione peroxidase activity
- Decreases malondialdehyde (MDA) content
- Inhibits UGT2B7 activity
- Attenuates ox-LDL-induced apoptosis, ROS generation, and cytotoxicity in endothelial cells
- Inhibits LDL oxidation and brain mitochondrial damage
- Research applications: Alzheimer's, atherosclerosis, brain ischemia, age-related brain deterioration