Unsubstituted Phenols
Medchemexpress LLC Dehydroxymethylepoxyquinomicin | 287194-40-5 | 99.8% | 261.23 | 2 MG
Dehydroxymethylepoxyquinomicin, also known as (-)-DHMEQ, is a potent, selective, and irreversible NF-κB inhibitor that covalently binds to a cysteine residue. This chemical compound is known to inhibit the nuclear translocation of NF-κB, which plays a crucial role in various cellular processes. It exhibits significant anti-inflammatory and anticancer activities.
- Potent and selective NF-κB inhibitor
- Irreversibly binds to a cysteine residue
- Inhibits nuclear translocation of NF-κB
- Exhibits anti-inflammatory activity
- Demonstrates anticancer activity
Medchemexpress LLC HY-N0356 10mg Medchemexpress, (-)-Catechin gallate CAS:130405-40-2 Purity:>98%
Medchemexpress, HY-N0356 10mg (-)-Catechin gallate CAS:130405-40-2 (-)-Catechin gallate is a minor constituent in green tea catechins. (-)-Catechin gallate inhibits the activity of COX-1 and COX-2 enzymes. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC ML-109 | 1186649-91-1 | 99.02% | 523.58 | 100 MG
ML-109 is a potent and full thyroid stimulating hormone receptor (TSHR) agonist, with an EC50 of 40 nM. It is for research use only.
- Potent and full agonist at TSHR with an EC50 of 40 nM.
- No activity at FSHR or LHCGR.
- Surprisingly stable under neutral and basic conditions (t1/2 of ~16 h), though it degrades at low pH (t1/2 of ~3 h).
Medchemexpress LLC ML-109 | 1186649-91-1 | 99.0% | 523.58 | 50 MG
ML-109 is identified as a potent and full agonist of the thyroid stimulating hormone receptor (TSHR), exhibiting an EC50 of 40 nM. While being surprisingly stable under neutral and basic conditions with a half-life of approximately 16 hours, it degrades at lower pH levels, with a half-life of about 3 hours. It shows no activity at FSHR or LHCGR.
- Potent and full thyroid stimulating hormone receptor (TSHR) agonist
- EC50 of 40 nM for TSHR
- No activity at FSHR or LHCGR
- Stable at neutral and basic conditions (t1/2 of ~16 h)
Selleck Chemical LLC IKK-16 S2882-50mg
IKK-16 is a selective I B kinase (IKK) inhibitor for IKK-2 IKK complex and IKK-1 with IC50 of 40 nM 70 nM and 200 nM in cell-free assays respectively IKK-16 also inhibits LRRK2 Ser935 phosphorylation in cells and LRRK2 kinase activity in vitro with IC50 of 50 nM
Apexbio Technology LLC L-690,330 142523-38-4 10mg
L-690 330 (CAS 142523-38-4) is a competitive inhibitor of inositol monophosphatase (IMPase) exhibiting a Ki between 0 2 and 2 M depending on the enzyme source IMPase catalyzes the hydrolysis of inositol monophosphates yielding free inositol for phosphatidylinositol (PI) cycle signaling In M1 CHO cells L-690 330 did not elevate [3H]InsP1 levels alone but attenuated carbachol-stimulated increases producing effects up to 40% of those observed with lithium In vivo L-690 330 administration led to significant Ins(1)P accumulation in mouse brain following muscarinic agonist stimulation These properties make L-690 330 a valuable tool for probing inositol signaling pathways and studying IMPase-related neurological processes
Medchemexpress LLC Liquiritigenin-7-O-β-D-glucopyranosyl-(1→2)-β-D-apiofuranoside | 135432-48-3 | 10 MG
Liquiritigenin-7-O-β-D-glucopyranosyl-(1→2)-β-D-apiofuranoside, also known as Liquiritigenin-7-apiosylglucoside, is a flavonoid isolated from the roots of Glycyrrhiza. It is recognized for exhibiting weaker cytotoxicity against various tumor cells and normal cells. This product is strictly for research use only and not intended for sale to patients.
- Source: Isolated from the roots of Glycyrrhiza.
- Activity: Flavonoid with weaker cytotoxicity against several tumor cells and normal cells.
- Purity: 99.74% confirmed.
- Appearance: Solid, light yellow to yellow in color.
- In vitro solubility: 100 mg/mL in DMSO (181.65 mM).
- In vivo solubility: Can be dissolved in various solvent systems such as 10% DMSO, 40% PEG300, 5% Tween-80, 45% Saline; 10% DMSO, 90% (20% SBE-β-CD in Saline); or 10% DMSO, 90% Corn Oil, with solubilities generally ≥ 2.5 mg/mL (4.54 mM).