Saturated hydrocarbons
Medchemexpress LLC Stearic acid-mPEG (MW 2000) | 99.64% | 2000 | 200 MG
Stearic acid-mPEG (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. It can be used in drug delivery research.
- Enhances delivery efficiency
- Improves tissue specificity
- Suitable for poorly soluble drugs
- Used in drug delivery research
Medchemexpress LLC 2-Methylcyclopentane-1,3-dione | 765-69-5 | 100.0% | 112.13 | 50 G
2-Methylcyclopentane-1,3-dione is a key intermediate for the total synthesis of steroids.
Medchemexpress LLC Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, (t-4)-tetrathioxomolybdate(2-) (2:1) | 649749-10-0 | 98.0% | 432.56 | 100 MG
ATN-224 is an orally active Cu2+/Zn2+-superoxide dismutase 1 (SOD1) inhibitor that inhibits SOD1 activity in endothelial cells in a dose-dependent manner with an IC50 of 17.5 nM.
- Specific and high affinity for copper ions.
- Inhibits the proliferation of HUVEC (IC50=1.4±0.3 μM).
- Inhibits the activity of purified bovine SOD1 with an IC50 of 0.33±0.03 μM.
- SOD1 inhibition is time-dependent, reaching maximal inhibition by depleting copper.
- Inhibits FGF-2-induced ERK1/2 phosphorylation.
- Orally-available inorganic small molecule that inhibits Cu/Zn-SOD1 in endothelial and tumor cells.
- Significantly inhibits angiogenesis in the Matrigel plug model in mice.
- Angiogenesis inhibition occurs independently of copper depletion.
Sigma Aldrich Fine Chemicals Biosciences Decane anhydrous, >=99% | 124-18-5 | MFCD00008954 | 100ML
Decane anhydrous, >=99% | Purity: >=99% | Mol Wt: 142.28 | 124-18-5 | MFCD00008954 | 100ML
Medchemexpress LLC I-287 | 2014368-93-3 | 99.4% | 565.04 | 1 ML
I-287 is an orally active, selective PAR2 inhibitor that acts as a negative allosteric regulator on Gαq and Gα12/13 activity and their downstream effectors. It has been shown to reduce Complete Freund's adjuvant-induced inflammation in mice and can be used for inflammation/immunology research.
- Inhibits PAR2-mediated activation of Gαq and Gα12/13
- Inhibits PAR2-mediated ERK1/2 activation in HEK293 cells
- Inhibits PAR2-induced secretion of IL-8 cytokine in HCT-116 and A549 cells
- Reduces Complete Freund's adjuvant-induced inflammation in C57BL/6J mice
Cayman Chemical Stearic Acid ethyl ester
Stearic acid is a saturated fatty acid commonly found in animal and vegetable fats that is frequently used in cosmetics, candles, soaps, plastics, oil pastels, and for softening rubber. Ethyl stearate is the neutral, more lipid soluble form of the free acid. It perturbs the cell cycle and induces apoptosis in Hep-G2 cells and is a marker of excessive alcohol consumption that can be isolated from an individual’s hair.{14158,14159}
Medchemexpress LLC Pentadecane | 629-62-9 | MFCD00008990 | 100 G
Pentadecane is a floral volatile antimalarial agent that can inhibit the growth of parasites such as Leishmania and avoid infection of macrophages. It has IC50s against promastigotes and amastigotes of 65.3 μM and 60.5 μM, respectively. This agent also exhibits anti-inflammatory, analgesic, and antipyretic activities.
- It is a floral volatile antimalarial agent.
- It inhibits the growth of parasites such as Leishmania.
- It helps avoid infection of macrophages.
- It possesses anti-inflammatory activities.
- It has analgesic properties.
- It demonstrates antipyretic activities.
Storage Conditions: Store at room temperature for 3 years. When in solvent, store at -80°C for 2 years or at -20°C for 1 year. For stock solutions, store at -80°C for 2 years or at -20°C for 1 year.
Medchemexpress LLC Octadecane | 593-45-3 | 1 G
Octadecane is an alkane used to store thermal energy at ambient temperature as a phase change material. It is for research use only and not sold to patients.
- Purity of 98.0%
- Molecular weight: 254.49
- Formula: C18H38
- Appearance: solid below 28°C, liquid above 28°C
- Color: colorless to off-white
- Melting/freezing point: 28°C
- Target: biochemical assay reagents
Cambridge Isotope Laboratories PFOS/PFOA Native Standard Mixture 1 2 mL
PFOS/PFOA Native Standard Mixture 1 2 mL