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Filtered Search Results
Medchemexpress LLC TRC-766 50 mg
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TRC-766 50MG
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Cayman Chemical cIs-VaccenIc AcId 500mg
An ω-7 fatty acid; induces differentiation of, and γ-globin synthesis in, K562 and JK-1 cells, as well as isolated sickle cell TMbmEPSCs
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Medchemexpress LLC α-Carotene | 7488-99-5 | ≥99.0% | 536.87 | 1 MG
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α-Carotene | 7488-99-5 | ≥99.0% | 536.87 | 1 MG
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Sigma Aldrich Fine Chemicals Biosciences 3-Phenyl-1-propyne contains ca.250 ppm BHT as inhibitor, 97% | 10147-11-2 | MFCD00134431 | 5G
3-Phenyl-1-propyne contains ca.250 ppm BHT as inhibitor, 97% | Purity: 97% | Mol Wt: 116.16 | 10147-11-2 | MFCD00134431 | 5G
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GRAINGER INC 2-METHYL-1-BUTENE 25ML
502781617 2-METHYL-1-BUTENE 25ML
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Apexbio Technology LLC I-BET-762 1260907-17-2 50mg
I-BET-762 (CAS 1260907-17-2) is a small-molecule inhibitor targeting the BET (bromodomain and extra-terminal) family of proteins It acts by competitively binding to the acetyl-lysine recognition pocket of BET bromodomains thereby displacing acetylated histones with an IC50 ranging from 32 5 to 42 5 nM and a dissociation constant (Kd) between 50 5 and 61 3 nM I-BET-762 displays high selectivity exhibiting no interaction with non-BET bromodomain-containing proteins In cellular studies it downregulates LPS-induced gene expression resulting in reduced production of pro-inflammatory cytokines and chemokines In vivo models demonstrate its potential to attenuate features of established inflammatory disease supporting its utility in epigenetic and inflammation-related research
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TARGETMOL CHEMICALS INC CWHM-1552 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CWHM-1552 is an effective Plasmodium falciparum inhibitor. For the 3D7 and Dd2 strains the IC50s are 51 nM and 53 nM. purity: 100%
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Sigma Aldrich Fine Chemicals Biosciences trans-2-Octene | 13389-42-9 | MFCD00009532 | 10g
trans-2-Octene | 97% | 112.21 | 13389-42-9 | MFCD00009532 | 10g
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Aobchem AOBCHEM
5001005810 PHENYLMETHYL 3-CYCLOPENTENE-1-
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Aobchem AOBCHEM
5001006493 PHENYLMETHYL 3-CYCLOPENTENE-1-
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Medchemexpress LLC Tau protein (592-597), human (TFA) | 2703746-44-3 | 95.2% | 868.94 | 25 MG
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Tau protein (592-597), human TFA, is a peptide fragment of human Tau protein. The dysfunction of Tau protein is involved in neurodegeneration and dementia, making this compound relevant for neurodegenerative disease research.
- Purity: 95.2%
- Molecular weight: 868.94
- Formula: C36H63F3N10O11
- Appearance: White to off-white solid
- Sequence: Ac-Val-Gln-Ile-Ile-Asn-Lys-NH2 (Ac-VQIINK-NH2)
- Solubility in H2O: ≥ 2 mg/mL (2.30 mM)
- Recommended storage for powder: -80°C for 2 years, -20°C for 1 year
- Recommended storage in solvent: -80°C for 6 months, -20°C for 1 month (sealed, away from moisture)
- For research use only
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Medchemexpress LLC DI-591 | 2245887-38-9 | 98.06% | 585.80 | 5 MG
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DI-591 is a potent, high-affinity, and cell-permeable inhibitor of the DCN1-UBC12 interaction. It selectively inhibits the neddylation of cullin 3, with minimal or no effect on other cullin family members.
- Binds to DCN1 and DCN2 with Ki values of 12 nM and 10.4 nM, respectively
- Shows no significant binding to DCN3, DCN4, and DCN5 proteins
- Serves as an excellent probe compound for investigating the role of cullin 3 CRL
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Medchemexpress LLC DI-591 | 2245887-38-9 | 98.4% | 585.80 | C31H47N5O4S | 50MG
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DI-591 is a potent, cell-permeable small-molecule inhibitor of the DCN1-UBC12 interaction that blocks cullin 3 neddylation. It is intended for biochemical and cellular research where inhibition of neddylation and modulation of ubiquitin-pathway signaling are required.
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Medchemexpress LLC VE-821 | 1232410-49-9 | 99.7% | 368.41 | 10 MM 1 ML
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VE-821 is a potent ATP-competitive inhibitor of ATR with a Ki/IC50 of 13 nM/26 nM. It exhibits excellent selectivity for ATR with minimal cross-reactivity against related PIKKs. This compound significantly enhances the sensitivity of pancreatic cancer cells to radiation and Gemcitabine, making it suitable for studies on DNA damage response and cancer therapy.
- Potent ATP-competitive inhibitor of ATR.
- Exhibits excellent selectivity for ATR.
- Enhances sensitivity of pancreatic cancer cells to radiation and Gemcitabine.
- Inhibits radiation-induced G2/M arrest in cancer cells.
- Soluble in DMSO (50 mg/mL).
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Medchemexpress LLC NO2A-butyne | 2089035-56-1 | 98.0% | 354.40 g/mol | C16H26N4O5 | 25mg
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NO2A-Butyneis a bifunctional chelator (Bifunctional Chelator BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting NO2A-Butyne can be used for conjugation of peptides and radionuclides
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