Boronic acid derivatives
Sigma Aldrich Fine Chemicals Biosciences 3-Hexylthiophene-2-boronic acid pinacol ester 95% | Purity: 95% | Mol Wt: 294.26 | 850881-09-3 | MFCD11045447 | 1G
3-Hexylthiophene-2-boronic acid pinacol ester 95% | Purity: 95% | Mol Wt: 294.26 | 850881-09-3 | MFCD11045447 | 1G
Cayman Chemical 8 9EpETE Fatty Acids and Deriv
An epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo
Cayman Chemical CAY10462, Purity: ≥98%, CAS: 502656-68-0, 5 mg
A selective inhibitor of the 20-HETE synthase CYP4A11 (IC50 = 8.8 nM in human renal microsomes); 200-fold less potent as an inhibitor of 1A, 1C, and 3A CYP450 enzymes
Cayman Chemical CAY10499, Purity: ≥98%, CAS: 359714-55-9, 5 mg
A non-selective lipase inhibitor (IC50s = 144, 90, and 14 nM for human recombinant MAGL, HSL, and FAAH, respectively); inhibits ATGL, DAGLa, ABHD6, and CES1 at 5 mM; inhibits the growth of MCF-7, MDA-MB-231, COV318, and OVCAR-3 cancer cells (IC50s = 4.2, 46, 106.7, and 79.8 µM, respectively); reduces FRUC diet- and AIN-93M diet-induced increases in cytosolic lipase activity in rats
Cayman Chemical 17 SHETE Fatty Acids and Deriv
A potent inhibitor of proximal tubule ATPase activity; is a CYP450 metabolite of arachidonic acid; inhibits proximal tubule ATPase activity by 70% at 2 µM
Cayman Chemical CAY10434, Purity: ≥98%, CAS: 769917-29-5, 50 mg
A selective inhibitor of the 20-HETE synthase CYP4A11 (IC50 = 8.8 nM human renal microsomes)
Cayman Chemical CAY10455 Fatty Acids and Deriv
A fluorescent substrate for AEA transport; cleavage by intracellular esterases gives a bright fluorescence at 530 nm
Cayman Chemical 17 RHDHA Fatty Acids and Deriv
An aspirin-induced DHA metabolite; a precursor to resolvins; inhibits TNF-α-induced IL-1β expression in human glioma cells
Cayman Chemical CAY10509, Purity: ≥98%, CAS: 1245699-47-1, 5 mg
Derivative of PGF1α containing a thio-fluorobenzene substituent in the lower side chain; binds to the recombinant human FP receptor with an IC50 value of about 30 nM
Cayman Chemical CAY10443, Purity: ≥98%, CAS: 582314-48-5, 10 mg
A pro-apoptotic activator of the apoptosome; activates caspase-3 (EC50 = 5 µM) in a cell-free assay
Cayman Chemical CAY10573, Purity: ≥98%, CAS: 853652-40-1, 10 mg
A PPAR agonist that displays potent binding at PPARα, γ, and δ (IC50s = 113, 50, 223 nM, respectively) and potently transactivates PPARα, γ, and δ (EC50s = 8, 70, 500 nM, respectively); demonstrates stronger binding and functional activity for PPARγ than rosiglitazone