Hydroxy acids and derivatives
DL-Carnitine hydrochloride, 99%
CAS: 461-05-2 Molecular Formula: C7H15NO3·HCl Molecular Weight (g/mol): 197.66 MDL Number: MFCD00011904 InChI Key: JXXCENBLGFBQJM-UHFFFAOYSA-O Synonym: dl-carnitine hydrochloride,3-carboxy-2-hydroxypropyl-trimethylammonium hydrochloride,2,4-bis oxidanyl-4-oxidanylidene-butyl-trimethyl-azanium hydrochloride PubChem CID: 24206429 IUPAC Name: (3-carboxy-2-hydroxypropyl)-trimethylazanium;hydrochloride SMILES: C[N+](C)(C)CC(CC(=O)O)O.Cl
Medchemexpress LLC 2-Hydroxyhexanoic acid | 6064-63-7 | MFCD00004584 | 99.95% | C6H12O3 | 5 G
2-Hydroxyhexanoic acid is a metabolite that is elevated in metastatic pancreatic neuroendocrine tumors. It does not promote the proliferation, migration, or invasion of pancreatic neuroendocrine tumor cells and can be used in the research of metastatic pancreatic neuroendocrine tumors.
- Metabolite elevated in metastatic pancreatic neuroendocrine tumors
- Does not promote proliferation, migration, or invasion of pancreatic neuroendocrine tumor cells
- Useful for research related to metastatic pancreatic neuroendocrine tumors
- Target: Human endogenous metabolite
Medchemexpress LLC 2-Hydroxyhexanoic acid | 6064-63-7 | 99.95% | C6H12O3 | 1 G
2-Hydroxyhexanoic acid is a metabolite elevated in metastatic pancreatic neuroendocrine tumors. It does not promote the proliferation, migration, or invasion of pancreatic neuroendocrine tumor cells, making it suitable for research into metastatic pancreatic neuroendocrine tumors.
- Elevated in metastatic pancreatic neuroendocrine tumors
- Does not promote proliferation, migration, or invasion of pancreatic neuroendocrine tumor cells
- Useful in research of metastatic pancreatic neuroendocrine tumors
- Classified as an endogenous metabolite
- Part of the ketones, aldehydes, acids structure classification
Medchemexpress LLC 2-Hydroxybutyric acid | 600-15-7 | 98.0% | 104.10 | 500 MG
2-Hydroxybutyric acid (α-Hydroxybutyric acid) is derived from 2-Aminobutyric acid, with 2-oxobutyric acid serving as an intermediate metabolite. It is recognized as a potential biomarker for type 2 diabetes and preeclampsia. This compound has also been shown to prevent acetaminophen (AP)-induced liver injury.
- Potential biomarker for type 2 diabetes and preeclampsia
- Prevents acetaminophen (AP)-induced liver injury
- Enhances cell viabilities and decreases AP-induced cytotoxicities
- Normalizes gene expressions involved in inflammation response, oxidative stress, cell proliferation, and DNA damage
Medchemexpress LLC Tylvalosin (tartrate) | 63428-13-7 | 96.0% | 50 MG
Tylvalosin tartrate is an orally active, broad-spectrum macrolide antibiotic and antiviral agent. It is useful in studying PRRSV infection, induces apoptosis, and possesses anti-inflammatory activity by relieving oxidative stress and alleviating acute lung injury through inhibiting NF-κB activation.
- Increases caspase-3 cleavage and promotes endocytosis in porcine neutrophils.
- Reduces stress and improves health in pigs during PRRSV vaccine immunization.
- Attenuates increase in white blood cells and reduction in CD8+ T cells after immunization.
- Relieves oxidative stress and alleviates acute lung injury by inhibiting NF-κB activation.
Medchemexpress LLC 2-hydroxybutyric acid (α-hydroxybutyric acid) | 600-15-7 | 98.0% | 104.10 | 1 G
2-Hydroxybutyric acid (α-Hydroxybutyric acid) is an endogenous metabolite, converted from 2-Aminobutyric acid. It serves as a potential biomarker for type 2 diabetes and preeclampsia and has shown the ability to prevent acetaminophen (AP)-induced liver injury. This compound is synthesized as a coproduct of insulin resistance, contributing to insulin signaling impairment and mitochondrial overload.
- Enhances cell viabilities and decreases AP-induced toxicities in BRL3A, AML12, and mice primary hepatocytes.
- Prevents AP-induced liver injury in C57 mice.
- Normalizes gene expressions related to inflammation response, oxidative stress, cell proliferation, and DNA damage.
Medchemexpress LLC 10-hydroxydecanoic acid | 1679-53-4 | MFCD00010510 | 99.8% | 188.26 | C10H20O3 | 50mg
10-Hydroxydecanoic acid (10-HDAA) is a saturated fatty acid derived from 10-hydroxy-trans-2-decenoic acid which can be isolated from royal jelly 10-Hydroxydecanoic acid exhibits various biological activities including anti-inflammatory insecticidal anti-malarial and anti-Leishmania properties as well as enhancing antigen-specific immune responses The anti-inflammatory effects of 10-Hydroxydecanoic acid are primarily mediated by inhibiting the activation of NF- B and the translation of interferon regulatory factor 1 (IRF-1) which reduces the production of interleukin 6 (IL-6) and nitric oxide (NO) in inflammatory cells Additionally 10-Hydroxydecanoic acid alleviates neuroinflammatory responses through the p53-autophagy pathway and the p53-NLRP3 pathway Finally 10-Hydroxydecanoic acid enhances antigen-specific immune responses by promoting the effective uptake of antigens by microfold cells[1][2][3][4][5]
Medchemexpress LLC 10-hydroxydecanoic acid | 1679-53-4 | MFCD00010510 | 99.8% | 188.26 g/mol | C10H20O3 | 1mL
10-Hydroxydecanoic acid (10-HDAA) is a saturated fatty acid derived from 10-hydroxy-trans-2-decenoic acid which can be isolated from royal jelly 10-Hydroxydecanoic acid exhibits various biological activities including anti-inflammatory insecticidal anti-malarial and anti-Leishmania properties as well as enhancing antigen-specific immune responses The anti-inflammatory effects of 10-Hydroxydecanoic acid are primarily mediated by inhibiting the activation of NF- B and the translation of interferon regulatory factor 1 (IRF-1) which reduces the production of interleukin 6 (IL-6) and nitric oxide (NO) in inflammatory cells Additionally 10-Hydroxydecanoic acid alleviates neuroinflammatory responses through the p53-autophagy pathway and the p53-NLRP3 pathway Finally 10-Hydroxydecanoic acid enhances antigen-specific immune responses by promoting the effective uptake of antigens by microfold cells[1][2][3][4][5]
Medchemexpress LLC Metoprolol tartrate | 56392-17-7 | 99.98% | 342.41 | 50 MG
Metoprolol tartrate is a selective β1-adrenoceptor antagonist that is orally active. It has demonstrated anti-inflammatory, antitumor, and anti-angiogenic properties. This compound is intended for research use only and exhibits dose and time-dependent cytotoxic effects on U937 and MOLT-4 cells in vitro, and reduces proinflammatory cytokines and atherosclerosis in ApoE-/- Mice in vivo.
- Selective β1-adrenoceptor antagonist.
- Orally active.
- Multi-faceted properties: anti-inflammatory, antitumor, and anti-angiogenic effects.
- Exhibits cytotoxic effects on U937 and MOLT-4 cells in vitro.
- Reduces proinflammatory cytokines and atherosclerosis in ApoE-/- Mice.
- Exhibits anti-inflammation and anti-virus effects in a murine model with coxsackievirus B3-induced viral myocarditis.
- Inhibits myocardial apoptosis in coronary microembolization (CME) rats.
Alkali Scientific Calcium Gluconate, Monohydrate, 250 G
Calcium Gluconate Monohydrate is a high-purity reagent provided in a 250g package, ideal for use in laboratory experiments involving calcium regulation or supplementation. It is commonly used in the preparation of buffered solutions, enzyme assays, and cell culture media that require precise calcium ion concentrations. Calcium Gluconate is also used in pharmaceutical applications, particularly in the development of oral and intravenous calcium supplements. Its versatility and high purity make it an essential reagent in both academic and industrial laboratories focusing on calcium-dependent processes in biochemical, clinical, and pharmaceutical research.
Alkali Scientific Calcium Gluconate, Monohydrate, 1 Kg
Calcium Gluconate Monohydrate is a high-purity laboratory reagent supplied in a 1 kg package. It is commonly used in various biochemical and analytical applications, particularly in studies involving calcium supplementation or regulation. This reagent is frequently used in the preparation of buffers, solutions for cell culture, and for calcium-dependent enzymatic reactions. Calcium Gluconate is also used in pharmaceutical applications, including the formulation of intravenous solutions and supplements. Its high purity ensures that it meets the strict requirements of laboratory and clinical research, providing reliable results in calcium-related biochemical experiments.
Medchemexpress LLC Metoprolol tartrate | 56392-17-7 | 100.0% | 342.41 | 200 MG
Metoprolol tartrate is an orally active, selective β1-adrenoceptor antagonist. It exhibits anti-inflammation, antitumor, and anti-angiogenic properties. This product is intended for research use only and is not sold to patients.
- Acts as a selective β1-adrenoceptor antagonist.
- Exhibits anti-inflammatory effects.
- Demonstrates antitumor properties.
- Shows anti-angiogenic effects.
- Cytotoxic to U937 and MOLT-4 cells.
- Reduces proinflammatory cytokines.
- Decreases myocardial virus titers.
- Inhibits myocardial apoptosis.
Apexbio Technology LLC PYRANTEL-TARTRATE-100MG
Pyrantel tartrate (CAS No 33401-94-4) is a compound classified under the category of antiparasitic agents primarily used in veterinary medicine It originates from tetrahydropyrimidines and functions as a cholinergic agonist targeting nicotinic acetylcholine receptors at the neuromuscular junction of nematodes This mechanism causes spastic paralysis in parasites facilitating their expulsion In vitro activity of pyrantel tartrate is generally observed in the nanomolar to low micromolar range depending on the organism It is commonly applied in studies involving cell models of nematode infections and is used in animal studies to evaluate its efficacy as an anthelmintic The compound is also utilized in drug screening efforts to discover new treatments for parasitic infections Experimental concentrations typically depend on the specific research design
Apexbio Technology LLC PYRANTEL-TARTRATE-500MG
Pyrantel tartrate (CAS No 33401-94-4) is a compound classified under the category of antiparasitic agents primarily used in veterinary medicine It originates from tetrahydropyrimidines and functions as a cholinergic agonist targeting nicotinic acetylcholine receptors at the neuromuscular junction of nematodes This mechanism causes spastic paralysis in parasites facilitating their expulsion In vitro activity of pyrantel tartrate is generally observed in the nanomolar to low micromolar range depending on the organism It is commonly applied in studies involving cell models of nematode infections and is used in animal studies to evaluate its efficacy as an anthelmintic The compound is also utilized in drug screening efforts to discover new treatments for parasitic infections Experimental concentrations typically depend on the specific research design
Medchemexpress LLC 2-Hydroxybutyric acid | 600-15-7 | 98.0% | 104.10 | 1 ML
2-Hydroxybutyric acid (α-Hydroxybutyric acid) is an endogenous metabolite converted from 2-Aminobutyric acid, with 2-oxobutyric acid as an intermediate. It is recognized as a potential biomarker for type 2 diabetes and preeclampsia. It has also been shown to prevent acetaminophen (AP)-induced liver injury.
- Derived from 2-Aminobutyric acid.
- Potential biomarker for type 2 diabetes and preeclampsia.
- Prevents acetaminophen-induced liver injury.
- Synthesized as a co-product of insulin resistance.
- Enhances cell viabilities and reduces AP-induced cytotoxicities in studies.
- Administration in C57 mice prevented AP-induced liver injury and normalized gene expression.
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