Organic phosphoric acids and derivatives
Apexbio Technology LLC KN-92 phosphate 1135280-28-2 5mg
KN-92 phosphate is a small-molecule analog of the Ca2 /calmodulin-dependent kinase II (CaMKII) inhibitor KN-93 It is designed as an inactive control compound to distinguish CaMKII-specific effects in experimental settings KN-92 phosphate does not inhibit CaMKII activity and thus serves as a negative control for CaMKII inhibition studies Additionally KN-92 phosphate blocks certain voltage-gated potassium (Kv) channels such as Kv1 2 and Kv1 5 reducing steady-state current amplitudes upon depolarization Based on these pharmacological properties KN-92 phosphate holds research potential in investigating mechanisms underlying CaMKII-related signaling pathways and Kv channel functions
Apexbio Technology LLC Estramustine phosphate sodium 52205-73-9 50mg
Estramustine phosphate sodium (CAS 52205-73-9) is an orally bioavailable small molecule that functions as an antimicrotubule agent Structurally related to estradiol it interacts with microtubule-associated proteins (MAPs) promoting microtubule disassembly and disrupting mitotic spindle formation This action interferes with mitosis ultimately leading to apoptotic cell death Widely studied in prostate cancer models estramustine phosphate sodium serves as a valuable tool for investigating mechanisms of cell cycle regulation mitotic arrest and apoptosis in oncological and cellular biology research settings
eMolecules 65094-22-6 | Diethyl (bromodifluoromethyl)phosphonate | Ambeed | MFCD00069118 | 267.007 | C5H10BrF2O3P | 97.000 | CCOP(=O)(OCC)C(F)(F)Br | 5g | 525113605
Diethyl (bromodifluoromethyl)phosphonate | Ambeed | 65094-22-6 | MFCD00069118 | 267.007 | C5H10BrF2O3P | 97.000 | CCOP(=O)(OCC)C(F)(F)Br | 5g | 525113605
Apexbio Technology LLC KN-93 Phosphate 1188890-41-6 5mg
KN-93 Phosphate (CAS 1188890-41-6) is a small-molecule inhibitor targeting calcium/calmodulin-dependent protein kinase II (CaMKII) It is designed to selectively inhibit CaMKII thereby modulating cellular proliferation survival neurotransmitter regulation and related signal transduction pathways KN-93 Phosphate exerts its biological activity primarily by competitively binding to Ca2 /calmodulin disrupting their interaction with CaMKII and preventing CaMKII activation and autophosphorylation In cell-based studies KN-93 Phosphate demonstrates inhibitory activity with IC50 values of 9 M for CaMKII monomer and 3 M for CaMKII dodecamer Experimental models include hepatic stellate cells and NIH 3T3 fibroblasts Based on these pharmacological properties KN-93 Phosphate holds research potential in the study of cell cycle regulation apoptosis neurotransmitter synthesis and neurodegenerative disorders particularly Parkinson s disease models
Medchemexpress LLC Phosphoramidous acid, N,N-bis(1-methylethyl)-, bis(phenylmethyl) ester | 108549-23-1 | ≥98.0% | 345.42 | 25 G
Dibenzyl diisopropylphosphoramidite is a biochemical reagent that can be used as a biological material or organic compound for life science-related research. It may be utilized for the preparation of phosphopeptides and is also employed in the synthesis of a GDP (guanosine diphosphate) analog, SML-8-73-1. Additionally, it is useful for nucleotide coupling.
- Biochemical reagent
- Can be used as a biological material or organic compound for life science related research
- May be used for the preparation of phosphopeptides
- Used for the synthesis of a GDP (guanosine diphosphate) analog, SML-8-73-1
- Useful for nucleotide coupling
Selleck Chemical LLC Fludarabine Phosphate S1229-1g
Fludarabine Phosphate is an analogue of adenosine and deoxyadenosine which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis
eMolecules 65094-22-6 | Diethyl (Bromodifluoromethyl)phosphonate | Accela ChemBio (ASD) | MFCD00069118 | 267.007 | C5H10BrF2O3P | 97.000 | CCOP(=O)(OCC)C(F)(F)Br | 100g | 444751349
Diethyl (Bromodifluoromethyl)phosphonate | Accela ChemBio (ASD) | 65094-22-6 | MFCD00069118 | 267.007 | C5H10BrF2O3P | 97.000 | CCOP(=O)(OCC)C(F)(F)Br | 100g | 444751349
Medchemexpress LLC Uzansertib phosphate | 2088852-47-3 | 99.5% | 611.51 g/mol | C26H29F3N5O7P | 100 MG
Uzansertib phosphate is the phosphate salt of uzansertib, an orally active, ATP-competitive pan-PIM kinase inhibitor supplied as a white to off-white solid for research use. The compound is used in biochemical and cellular assays to investigate PIM kinase activity and JAK/STAT signaling.
- High purity (99.5%) suitable for research applications.
- Solid powder form, easy to weigh and store.
- Molecular formula C26H29F3N5O7P and molecular weight 611.51 g/mol.
- Used in biochemical kinase assays and cellular proliferation studies.
- Soluble in DMSO for assay preparation.
Apexbio Technology LLC Tylosin phosphate 1405-53-4 5g
Tylosin phosphate (CAS 1405-53-4) is a small-molecule inhibitor targeting bacterial ribosomal subunits It is designed to interfere with bacterial translation thereby inhibiting bacterial protein synthesis Tylosin phosphate exerts its biological activity primarily through binding to ribosomal subunits of Gram-positive bacteria In in vitro studies tylosin phosphate demonstrates inhibitory activity with reported IC50 values generally ranging between 0 5 5 g/mL depending on bacterial strain and assay conditions Based on these pharmacological properties tylosin phosphate holds research potential in studies of antibiotic resistance mechanisms antibacterial spectrum evaluation and as an antibiotic additive to explore growth promotion and therapeutic utility in poultry swine and bovine models
Medchemexpress LLC Glutathione diethyl ester (TFA) | 97.35% | 477.45 | 1 MG
Glutathione diethyl ester (TFA) is a delivery agent for glutathione monoester, and consequently for glutathione, in human cells. It can potentially reduce oxidative stress and toxicity. This product is for research use only and is not sold to patients.
- Delivery agent for glutathione monoester
- May decrease oxidative stress
- May decrease toxicity
- Classified as an endogenous metabolite
- Relevant to metabolic and neurodegenerative disease research
- Also used in neurological and eye or ear disease research
- A peptide derivative and natural product standard
Medchemexpress LLC (E)-KN-93 phosphate | 1188890-41-6 | 99.85% | 599.03 | 1 ML
(E)-KN-93 phosphate is an inhibitor for Ca2+/calmodulin-dependent protein kinase II (CaMK II) with IC50 of 9 μM and 3 μM, for CaMKIIδ monomer and CaMKIIδ dodecamer. It binds competitively with Ca2+/CaM, disrupting their interaction with CaMK II, and thus inhibiting CaMK II activation.
- Inhibitor for Ca2+/calmodulin-dependent protein kinase II (CaMK II)
- Binds competitively with Ca2+/CaM
- Disrupts interaction with CaMK II
- Inhibits CaMK II activation
Medchemexpress LLC Plp (180-199) TFA | 99.2% | 2085.34 | 5 MG
PLP (180-199) TFA is the TFA salt form of PLP (180-199) (HY-P5462). It induces the activation and differentiation of T cells, and also induces experimental autoimmune encephalomyelitis (EAE) in a mouse model. This product is for research use only.
- TFA salt form of PLP (180-199)
- Induces activation and differentiation of T cells
- Induces experimental autoimmune encephalomyelitis (EAE) in mouse models
- Purity: 99.2%
- Molecular weight: 2085.34 (free base)
Medchemexpress LLC Trans,trans-dibenzylideneacetone | 35225-79-7 | 99.9% | 234.30 | 5 G
trans,trans-Dibenzylideneacetone, also known as (E,E)-Dibenzylideneacetone or trans,trans-Dibenzalacetone, is a dibenzylideneacetone compound. It exhibits weak antimalarial activity, shown to inhibit the *P. falciparum* 3D7 strain with an IC50 of 213.41 μM.
- High purity of 99.87%
- Solid, light yellow to yellow appearance
- Molecular weight of 234.30
- Chemical formula C17H14O
- Stable for 3 years at room temperature
- Inhibits *P. falciparum* 3D7 strain