Organic sulfonic acids and derivatives
Medchemexpress LLC Diphenylamine hydrochloride | 537-67-7 | 1 G
Diphenylamine hydrochloride (N-Phenylaniline hydrochloride) is an antihyperglycemic agent with oral activity and shares a common structure with non-steroidal anti-inflammatory drugs (NSAIDs). It functions by uncoupling oxidative phosphorylation in mitochondria, which can lead to a decrease in hepatic cell ATP levels and potential liver cell damage. Additionally, it serves as an industrial antioxidant, a dyeing mordant, and finds use in agriculture as both an antifungal and antibacterial agent.
- Antihyperglycemic agent with oral activity
- Functions as an industrial antioxidant
- Acts as a dyeing mordant
- Used as an antifungal agent in agriculture
- Used as an antibacterial agent in agriculture
- Uncouples oxidative phosphorylation in mitochondria
- Leads to decreased hepatic cell ATP levels
Enzo Life Sciences Imatinib. mesylate (500mg). CAS: 220127-57-1
Tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). Also shown to inhibit the transmembrane receptor kit and platelet-derived growth factor (PDGF) receptors. Alternative name: STI-571, CGP-57148B. Purity: ≥98% (HPLC). Appearance: White to pale yellow crystalline powder. Solubility: Soluble in water (200mg/ml) or DMSO (100mg/ml) or DMF (10mg/ml) or PBS (2mg/ml). Sparingly soluble in ethanol (0.2mg/ml). Storing aqueous solutions for more than one day is not recommended. Long Term Storage: +4°C.
Medchemexpress LLC Diphenylamine hydrochloride | 537-67-7 | 1 ML
Diphenylamine hydrochloride (N-Phenylaniline hydrochloride) is an antihyperglycemic agent with oral activity. It functions as an industrial antioxidant, a dyeing mordant, and an antifungal and antibacterial agent in agriculture. It is intended for research use only and not sold to patients.
- Shares a common structure with non-steroidal anti-inflammatory drugs (NSAIDs)
- Works by uncoupling oxidative phosphorylation in mitochondria
- Can lead to a decrease in hepatic cell ATP levels and may cause liver cell damage
- Excreted through urine and bile in rats
- Reduced blood sugar by 61.4% in hyperglycemic rabbits at 10 mg/kg oral dose
Medchemexpress LLC Polystyrene sulfonic acid | 28210-41-5 | 500 G
Polystyrene sulfonic acid (30% in water) is a chemical offered in solution packaging. Research indicates that polystyrene-derived microplastics (PS-MPs) may be harmful, with studies showing adverse effects on zebrafish hearts and induction of male reproductive toxicity in mice.
- Microplastics derived from polystyrene sulfonic acid can enter testicular cell lines in vitro.
- May lead to decreased sperm quality and testosterone levels in mice.
- Demonstrated adverse effects on zebrafish activity and heart tissue contraction.
- Observed to accumulate in the testis of mice.
- Induced testicular inflammation and disruption of the blood-testis barrier in mice.
Medchemexpress LLC Polystyrene sulfonic acid | 28210-41-5 | 100 G
Polystyrene sulfonic acid (30% in water) is a potentially toxic hazardous substance. It is for research use only and not sold to patients. MedChemExpress offers these Polystyrene products in solution packaging.
- Harmful to zebrafish hearts and induces male reproductive toxicity in mice
- PS-MPs at 0.5 μm, 4 μm, and 10 μm particle sizes can enter three testicular cell lines (GC-1 cell line) in vitro
- PS-MPs lead to decreased sperm quality and testosterone levels in mice
- PS-MPs accumulate in the testis of mice
- Induces testicular inflammation and disruption of the blood-testis barrier in mice
Medchemexpress LLC Docusate Sodium (Dioctyl sulfosuccinate sodium salt) | 577-11-7 | MFCD00012455 | 98.0% | 500 MG
Docusate Sodium is a sulfated surfactant that is a main component in stool softeners. It may inactivate viral pathogens by disrupting viral envelopes and/or denaturing/disassociating proteins. It has shown effectiveness in vitro against wild type and drug-resistant strains of HSV type 1 and 2. Docusate Sodium is also identified as an obesogen; developmental exposure to it in mice leads to increased adult adiposity, inflammation, metabolic disorder, and dyslipidemia in offspring fed a standard diet.
- Main component in stool softeners
- Inactivates viral pathogens by disrupting viral envelopes and/or denaturing proteins
- Effective against wild type and drug-resistant strains of HSV type 1 and 2
- Identified as an obesogen
Medchemexpress LLC Polystyrene sulfonic acid | 28210-41-5 | 30% | 50 G
Polystyrene sulfonic acid (30% in water) is provided as a potentially toxic hazardous substance, available in solution packaging for research use only. In vitro and in vivo studies have shown that polystyrene-derived microplastics (PS-MPs) can enter testicular cells, leading to decreased sperm quality, testosterone levels, and testicular inflammation in mice. Furthermore, PS-MPs have been observed to cause adverse effects on zebrafish activity, oxidative stress, metabolic changes, and contraction parameters in heart tissue.
- Suitable for research applications only
- Provided in solution packaging
- Studies indicate potential for male reproductive toxicity in mice, including decreased sperm quality and testosterone levels
- Demonstrates adverse effects on zebrafish activity and heart tissue, including oxidative stress and metabolic changes
- PS-MPs with specific particle sizes have been shown to accumulate in the testis of mice