Azetidines
![Sigma Aldrich [6-(2-Me-1,3-thiazol-4-yl)-3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl]acetic acid](https://assets.fishersci.com/TFS-Assets/CCG/Sigma-Aldrich/product-images/02dd13e0-d252-475a-b892-bc9e1107780b.jpg-250.jpg)
Sigma Aldrich [6-(2-Me-1,3-thiazol-4-yl)-3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl]acetic acid
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich Azetidine
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 2-(Chloromethyl)-6-methyl-1H-1,3-benzodiazole
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
![Sigma Aldrich 3-Allyl-4-[(4-iodobenzyl)oxy]-5-methoxybenzaldehyde](https://assets.fishersci.com/TFS-Assets/CCG/Sigma-Aldrich/product-images/63008b8a-0d63-4c6c-aa4f-ace25b7f274b.jpg-250.jpg)
Sigma Aldrich 3-Allyl-4-[(4-iodobenzyl)oxy]-5-methoxybenzaldehyde
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 5-Chloro-2-nitrotoluene
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich Tetrabenzyl pyrophosphate
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 3,5-Dichlorobenzyl alcohol
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich Azetidine hydrochloride
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Medchemexpress LLC Azetidine-3-carboxylic acid | 36476-78-5 | MFCD00191763 | 98.0% | 101.10 | C4H7NO2 | 25 G
Azetidine-3-carboxylic acid is a small-molecule building block used in medicinal chemistry for bioconjugation and linker synthesis. It serves as a non-cleavable ADC linker and as an alkyl chain-based PROTAC linker, and is supplied as a powder with defined storage conditions.
Medchemexpress LLC Fmoc-azetidine-3-carboxylic acid | 193693-64-0 | MFCD01321018 | 99.9% | 323.35 | C19H17NO4 | 25 G
Fmoc-azetidine-3-carboxylic acid is an Fmoc-protected amino acid derivative used as a building block in peptide synthesis and as a linker component in ADC and PROTAC chemistry. It is supplied for research use and is characterized by defined molecular properties and high purity.
- Fmoc-protected azetidine-3-carboxylic acid used in peptide synthesis.
- Suitable as a cleavable ADC linker and for PROTAC linker chemistry.
- High purity suitable for research applications.
- Molecular formula C19H17NO4 and molecular weight 323.35.
- Available in multiple pack sizes, including 25 g.
Medchemexpress LLC Azetidine-3-carboxylic acid | 36476-78-5 | MFCD00191763 | 101.10 | C4H7NO2 | 10 G
Azetidine-3-carboxylic acid is a small heterocyclic carboxylic acid used as a building block in medicinal and linker chemistry, including applications in ADC and PROTAC synthesis.
- Small four-membered heterocyclic carboxylic acid building block.
- Used in linker and medicinal chemistry, including ADC and PROTAC synthesis.
- Physical form: powder suitable for storage under recommended conditions.
- Molecular formula C4H7NO2 and molecular weight 101.10.
- Storage stability: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC 1-(tert-butoxycarbonyl)azetidine-3-carboxylic acid | 142253-55-2 | MFCD01860897 | 98.3% | 201.22 g/mol | C9H15NO4 | 1 G
1-(tert-butoxycarbonyl)azetidine-3-carboxylic acid is a Boc-protected azetidine derivative used as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and as an alkyl chain-based PROTAC linker. It is supplied as a high-purity white crystalline powder, suitable for medicinal chemistry and organic synthesis workflows.
- Boc-protected azetidine scaffold suitable for linker chemistry.
- High purity for reliable synthesis and characterization.
- Available in multiple package sizes for small-scale and bulk use.
- Soluble in DMSO for common synthetic procedures.
- Systematic name and identifiers available for database referencing.
Medchemexpress LLC 1-Cbz-azetidine-3-carboxylic acid | 97628-92-7 | MFCD09027504 | 99.6% | 235.24 | C12H13NO4 | 25 G
1-Cbz-azetidine-3-carboxylic acid is an N-protected azetidine carboxylic acid used as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and as an alkyl chain linker for PROTAC construction. It is supplied as a white to off-white solid with high purity suitable for medicinal chemistry and bioconjugation applications.
- non-cleavable ADC linker for antibody-drug conjugates
- alkyl chain-based PROTAC linker for targeted protein degradation
- high purity (99.6%) suitable for synthesis and conjugation
- soluble in DMSO at 100 mg/mL; may require ultrasonic
- stable as powder at -20°C for long-term storage, or 4°C for shorter term
Medchemexpress LLC 1-Boc-D-azetidine-2-carboxylic acid | 228857-58-7 | MFCD01320888 | 99.0% | 201.22 g/mol | C9H15NO4 | 5 G
1-Boc-D-azetidine-2-carboxylic acid is a Boc-protected D-azetidine amino acid derivative used as a synthetic intermediate in medicinal chemistry and organic synthesis. The N-Boc protection facilitates selective amine protection and subsequent coupling or derivatization of the azetidine ring, enabling preparation of azetidine-containing active compounds and building blocks.
- Boc-protected azetidine scaffold for versatile synthetic transformations.
- High purity (≈99.0%).
- Molecular weight 201.22 g/mol; formula C9H15NO4.
- Available in multiple small-scale pack sizes for laboratory synthesis.
- Stable as a solid at room temperature for up to 3 years; in solvent, long-term storage at -80°C.
- Suitable as a building block for medicinal chemistry and lead optimization.
Selleck Chemical LLC Azetidine-2-carboxylic acid
Azetidine-2-carboxylic acid (L-Aze) is a toxic and teratogenic non-protein amino acid that is misincorporated into protein in place of proline altering collagen keratin hemoglobin and protein folding