Azobenzenes
amino]-N-phenyl | 2305052-86-0 | 98.8% | C21H17ClN4O2 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC 2-Pyridinecarboxamide, 5-[[(6-chloro-2-pyridinyl)methyl](1-oxo-2-propen-1-yl)amino]-N-phenyl | 2305052-86-0 | 98.8% | C21H17ClN4O2 | 100 MG
BPK-25 is an active acrylamide that promotes the degradation of nucleosome remodeling and deacetylation (NuRD) complex proteins through a post-translational mechanism involving covalent protein engagement. It also inhibits TMEM173 activation by the cyclic dinucleotide ligand cGAMP.
- Promotes degradation of NuRD complex proteins.
- Inhibits TMEM173 activation.
- Active acrylamide.
- Intended for research and analytical applications.
eMolecules 104-23-4 | 4'-Aminoazobenzene-4-sulphonic acid | Combi-Blocks | MFCD00035778 | 277.300 | C12H11N3O3S | 97.000 | Nc1ccc(cc1)\N=N\c1ccc(cc1)S(O)(=O)=O | 1g | 205402053
4'-Aminoazobenzene-4-sulphonic acid | Combi-Blocks | 104-23-4 | MFCD00035778 | 277.300 | C12H11N3O3S | 97.000 | Nc1ccc(cc1)\N=N\c1ccc(cc1)S(O)(=O)=O | 1g | 205402053
![eMolecules 2135768-85-1 | Ambeed | 361114-Tetrabromodibenzo[ac]triphenylene | 100mg | 570572494 | A1363255 | 643.998 | C26H12Br4](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502484932.JPG-250.jpg)
eMolecules 2135768-85-1 | Ambeed | 361114-Tetrabromodibenzo[ac]triphenylene | 100mg | 570572494 | A1363255 | 643.998 | C26H12Br4
Medchem Express | Y16 | 5mg | 446261586 | HY-12649 | 429653-73-6 | MFCD03083787 | 384.435 | C24H20N2O3
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![Medchemexpress LLC 2-methylsulfanyl-6-[4-[3-[3-(trifluoromethyl)anilino]-1H-1,2,4-triazol-5-yl]phenoxy]pyrimidin-4-amin | 877874-85-6 | MFCD22124522 | 99.8% | 459.45 | C20H16F3N7OS | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000287497.png-250.jpg)
Medchemexpress LLC 2-methylsulfanyl-6-[4-[3-[3-(trifluoromethyl)anilino]-1H-1,2,4-triazol-5-yl]phenoxy]pyrimidin-4-amin | 877874-85-6 | MFCD22124522 | 99.8% | 459.45 | C20H16F3N7OS | 10 MG
KG5 is an orally active small-molecule allosteric inhibitor that targets PDGFRβ and B-Raf, with additional inhibitory activity against Flt3, KIT, and c-Raf. It demonstrates anticancer and antiangiogenic effects in cellular and animal models, including inhibition of MEK/ERK signaling and suppression of tumor growth and angiogenesis in vivo.
- Orally active allosteric inhibitor of PDGFRβ and B-Raf.
- Also inhibits Flt3, KIT, and c-Raf, broadening kinase coverage.
- Demonstrated anticancer and antiangiogenic activity in vitro and in vivo.
- Disrupts MEK/ERK phosphorylation and blocks S338 phosphorylation in endothelial cells.
- Potent cellular activity with EC50 values near 0.5-0.6 μM in vascular and endothelial cells.
- High purity suitable for research applications.
- Soluble in DMSO at high concentration and formulatable for in vivo dosing.
- Stable under recommended storage conditions to preserve activity.
eMolecules 21272-85-5 | Ambeed | Nitromethylphenylsulfone | 250mg | 686660269 | A592579 | MFCD00015928 | 201.2 | C7H7NO4S
Medchem Express | NNMTi | 5mg | 569407541 | HY-131042 | 42464-96-0 | 286.116 | C10H11IN2
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eMolecules 2204290-85-5 | Medchem Express | FzM1.8 | 10mg | 533802341 | HY-117163 | 322.32 | C18H14N2O4
AstaTech | ISOPROPYL METHYL SULFONE | 1g | 718084299 | D91166 | 95.000 | 4853-74-1 | MFCD00050415 | 122.180 | C4H10O2S
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Medchemexpress LLC Vacuolin-1 | 351986-85-1 | MFCD00321410 | 98.5% | 577.42 g·mol^-1 | C26H24IN7O | 10 MG
Vacuolin-1 is a cell-permeable small-molecule inhibitor of lysosomal exocytosis and PIKfyve used to study lysosome function and autophagy pathways.
- High purity suitable for in vitro research.
- Cell-permeable and active in cellular assays.
- Induces vacuolation of endolysosomal compartments.
- Soluble in DMSO for preparation of concentrated stock solutions.
- Stable when stored under recommended conditions.
![Medchemexpress LLC 3H-pyrrolo[2,3-d]pyrimidine-4,6-dione derivative (pentafluoropropoxy, trifluoroethoxy phenyl) | 1236767-85-3 | 99.9% | 473.27 g·mol^-1 | C17H11F8N3O4 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000227849.png-250.jpg)
Medchemexpress LLC 3H-pyrrolo[2,3-d]pyrimidine-4,6-dione derivative (pentafluoropropoxy, trifluoroethoxy phenyl) | 1236767-85-3 | 99.9% | 473.27 g·mol^-1 | C17H11F8N3O4 | 25 MG
D5D-IN-326 is a selective, orally active delta-5 desaturase inhibitor provided for research use. It shows low-nanomolar activity against human and rat D5D and is used in biochemical, cellular, and in vivo studies related to fatty acid metabolism and metabolic disease models.
- Selective delta-5 desaturase inhibitor with IC50 ≈ 22 nM (human) and 72 nM (rat).
- High purity (99.9%) suitable for biochemical and cellular assays.
- Supplied as a laboratory-scale powder, typical quantity 25 MG.
- Molecular formula C17H11F8N3O4, molecular weight 473.27 g·mol^-1.
- Recommended storage: powder at -20°C for long-term stability.
Medchemexpress LLC EPQpYEEIPIYL | 147612-86-0 | 99.5% | 1473.52 | 10 MG
EPQpYEEIPIYL is a phosphopeptide that functions as a Src homology 2 (SH2) domain ligand. It activates Src family members such as Lck, Hck, and Fyn by binding to their SH2 domains.
- Functions as a phosphopeptide and a Src homology 2 (SH2) domain ligand.
- Activates Src family members such as Lck, Hck, and Fyn.
- Exhibits high-affinity binding to GST fusion proteins of the Lck SH2 domain and the Src SH2 domain.
- For research use only.
Medchemexpress LLC 1-(3,4-dihydroxy-5-nitrophenyl)-2-phenylethanone | 274925-86-9 | MFCD09954136 | 99.9% | 273.24 g·mol-1 | C14H11NO5 | 10 MG
Nebicapone is a reversible catechol-O-methyltransferase (COMT) inhibitor supplied as a research-grade small molecule for preclinical pharmacology and biochemical studies. It acts mainly in the periphery to reduce conversion of L-DOPA to 3-O-methyl-DOPA and is used in experiments modeling COMT modulation and Parkinson's disease-related pathways.
- Reversible COMT inhibitor with peripheral activity.
- Reduces biotransformation of L-DOPA to 3-O-methyl-DOPA.
- Suitable for in vitro and in vivo pharmacology studies.
- Provided as solid doses (for example, 10 mg) and a 10 mM DMSO solution.
- High purity (99.89%) for research applications.
- Soluble in DMSO at ≥100 mg/mL; in vivo formulation protocols available.
- Store solid at 4°C protected from light; in solvent store at -80°C for long term or -20°C for short term.
eMolecules 1221962-86-2 | Medchem Express | PS210 | 5mg | 600899855 | HY-121629 | 380.319 | C19H15F3O5
Ambeed | (S)-3-(1-Aminoethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one | 100mg | 600845542 | A679385 | 1350643-72-9 | MFCD23166427 | 298.770 | C17H15ClN2O
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eMolecules 129544-85-0 | Medchem Express | MIND4-19 | 5mg | 721434759 | HY-147233 | MFCD01614372 | 373.47 | C22H19N3OS
ChemScene | 222-Trifluoro-1-(4-(trifluoromethyl)phenyl)ethanol | 100mg | 712788673 | CS-0436388 | 150698-81-0 | MFCD16067901 | 244.136 | C9H6F6O
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Medchemexpress LLC Spdmv | 890409-85-5 | 96.4% | 354.44 g/mol | C15H18N2O4S2 | 100 MG
SPDMV is a glutathione-cleavable antibody-drug conjugate (ADC) linker supplied for research use. It is designed to connect antibodies to cytotoxic payloads and release the payload intracellularly via glutathione-mediated cleavage.
- Glutathione-cleavable disulfide linker.
- Intended for ADC synthesis and conjugation chemistry.
- Purity 96.37%.
- CAS number 890409-85-5.
- Molecular weight 354.44 g/mol.
- Chemical formula C15H18N2O4S2.
- Available in 100 MG vial.
Medchemexpress LLC Atuliflapon (AZD5718) | 2041075-86-7 | 99.0% | 5 MG
Atuliflapon (AZD5718) is a potent, orally active small-molecule inhibitor of FLAP (5-lipoxygenase activating protein) supplied as a solid research compound. It is reported to have an IC50 of 2 nM and is provided with high purity and defined storage conditions for preclinical and in vitro studies.
- Potent FLAP inhibitor (IC50 ~2 nM)
- White to off-white solid powder form
- Molecular formula C24H26N6O3, molecular weight 446.50 g/mol
- Reported purity 98.97%
- Storage: powder -20°C (long term) or 4°C (short term)
- Intended for research use only
eMolecules 864716-85-8 | Medchem Express | Mesendogen | 5mg | 784543571 | HY-103073 | MFCD03991832 | 400.84 | C18H16ClF3N2OS
Medchem Express | Mesendogen | 5mg | 784543571 | HY-103073 | 864716-85-8 | MFCD03991832 | 400.840 | C18H16ClF3N2OS