Azobenzenes
Medchemexpress LLC EPQpYEEIPIYL | 147612-86-0 | 99.5% | 1473.52 | 1 MG
EPQpYEEIPIYL is a phosphopeptide that functions as a Src homology 2 (SH2) domain ligand. It activates members of the Src family, such as Lck, Hck, and Fyn, by binding to their SH2 domains. The phosphopeptide pY324, derived from hmT with the sequence EPQpYEEIPIYL, exhibits high-affinity binding to GST fusion proteins of the Lck SH2 domain and the Src SH2 domain. This product is used in cancer and cancer targeted therapy research, and is related to the protein tyrosine kinase/RTK pathway.
- Phosphopeptide and Src homology 2 (SH2) domain ligand
- Activates Src family members such as Lck, Hck, and Fyn
- High-affinity binding to GST fusion proteins of Lck SH2 domain and Src SH2 domain
- Soluble in H2O at 2 mg/mL (1.36 mM) with ultrasonic treatment and pH adjustment to 2 with HCl
- Used in cancer and cancer targeted therapy research
- Related to the protein tyrosine kinase/RTK pathway
Medchemexpress LLC Manool | 596-85-0 | 290.48 | 100 MG
Manool is a diterpene derived from *Salvia officinalis*. It selectively induces cytotoxicity in cancer cells and arrests them at the G(2)/M phase of the cell cycle. For research use only.
- Diterpene from *Salvia officinalis*.
- Induces selective cytotoxicity in cancer cells.
- Arrests cancer cells at the G(2)/M phase of the cell cycle.
- Exhibits higher cytotoxic activity against HeLa (IC50=6.7 μg/mL) and U343 (IC50=6.7 μg/mL) cells.
- Shows a protective effect against chromosome damage induced by MMS in HepG2 cells.
eMolecules 2757082-86-1 | Ambeed | (4R5R)-45-Diphenyl-2-(5-(trifluoromethyl)pyridin-2-yl)-45-dihydrooxazole | 100mg | 633418067 | A1349930 | 368.359 | C21H15F3N2O
Medchem Express | Antidepressant agent 1 | 5mg | 532149316 | HY-136171 | 67411-41-0 | 319.246 | C16H19BrN2
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Medchemexpress LLC 2-(3-oxo-1-phenyl-3-(4-(trifluoromethyl)phenyl)propyl)malonic acid | 1221962-86-2 | 98.3% | 25 MG
PS210 is a small-molecule activator of 3-phosphoinositide-dependent protein kinase-1 (PDK1) that engages the PIF-binding pocket and is used as a research reagent to study PDK1 signaling.
- Potent and selective PDK1 activator for research use.
- CAS number 1221962-86-2 for unambiguous identification.
- Molecular formula C19H15F3O5 and molecular weight 380.31 g·mol⁻¹.
- High purity (≈98%) suitable for biochemical assays.
- Supplied as a solid powder; recommended storage at -20°C for long-term stability.
- Available in small research pack sizes (25 mg) for laboratory studies.
Medchemexpress LLC Lupiwighteone | 104691-86-3 | 99.5% | 338.35 | C20H18O5 | 10 MG
Lupiwighteone is an isoflavone research compound used as a biochemical probe for studies of antioxidant, antimicrobial, and anticancer activity. It induces caspase-dependent and -independent apoptosis in cancer cells through inhibition of the PI3K/Akt/mTOR pathway. The material is supplied as a small solid suitable for preparation of DMSO stocks and in vivo formulation.
- Isoflavone small molecule for in vitro and in vivo research.
- Induces apoptosis via PI3K/Akt/mTOR pathway inhibition.
- Solubility: DMSO 100 mg/mL (in vitro); ≥2.5 mg/mL in 10% DMSO/90% corn oil (in vivo).
- Storage: store at 4°C, protect from light; in solvent -80°C (6 months) or -20°C (1 month).
- Key identifiers: CAS 104691-86-3; formula C20H18O5; molecular weight 338.35.
Medchemexpress LLC N-cycloheptyl-6,7-dimethoxy-2-(4-piperidin-1-ylpiperidin-1-yl)quinazolin-4-amine | 864289-85-0 | 100.0% | 467.65 g/mol | C27H41N5O2 | 10 MG
C-021 is a small-molecule CCR4 antagonist (CAS 864289-85-0) provided as a high-purity solid for research use. It is intended for in vitro and in vivo pharmacology studies where CCR4 inhibition is required. Supplied quantity: 10 mg; follow recommended solvent and storage guidance when preparing solutions.
- Potent CCR4 antagonist for pharmacological research.
- High purity (99.95%).
- Solid powder form suitable for dissolution in DMSO or ethanol.
- Soluble in DMSO or ethanol at 50 mg/mL (~106.9 mM).
- Powder storage: -20°C for long-term stability; in-solution storage: -80°C recommended.
- CAS number: 864289-85-0.
eMolecules 1091-85-6 | Ambeed | 2-(5-(Dimethylamino)naphthalene-1-sulfonamido)acetic acid | 250mg | 586458002 | A836722 | MFCD00037734 | 308.35 | C14H16N2O4S
AstaTech | 5-BROMO-6-METHYL-1H-BENZIMIDAZOLE | 0.25g | 296384823 | W10484 | 95.000 | 116106-16-2 | MFCD11846340 | 211.062 | C8H7BrN2
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Medchemexpress LLC Cdc7-IN-5 | 1402057-86-6 | 96.0% | 100 MG
Cdc7-IN-5 is a potent Cdc7 kinase inhibitor. This compound is extracted from patent WO2019165473A1 and targets Cdc7, a serine-threonine protein kinase enzyme essential for initiating DNA replication in the cell cycle.
- Potent Cdc7 kinase inhibitor
- Extracted from patent WO2019165473A1
- Targets serine-threonine protein kinase enzyme Cdc7
- Essential for DNA replication initiation
- Appearance: solid, white to light yellow
- Molecular weight: 445.47
- Molecular formula: C25H23N3O5
Medchemexpress LLC WWL113 | 947669-86-5 | 99.7% | 466.53 | 1 ML
WWL113 is a selective and orally active Ces3 and Ces1f inhibitor, with IC50 values of 120 nM and 100 nM for Ces3 and Ces1f, respectively. It appears to show excellent selectivity for the 60-kDa serine hydrolase (or hydrolases).
- Inhibits mouse recombinant Ces1, Ces1c, and ABHD6 at 10 μM.
- Significantly increases UCP1 protein expression in brown adipocytes at 1 μM.
- Has a partial, statistically significant inhibitory effect on blocking the buildup of PGE2.
- Results in major improvement of multiple features of metabolic syndrome and ameliorated obesity-diabetes in mice with lowered levels of nonesterified free fatty acids (NEFAs), triglycerides (TGs), total cholesterol and fasted glucose as well as enhanced glucose tolerance (30 mg/kg, orally once a day).
- Ameliorates obesity-diabetes in mice.
Medchemexpress LLC 2-Pyridinecarboxamide, 5-[[(6-chloro-2-pyridinyl)methyl](1-oxo-2-propen-1-yl)amino]-N-phenyl | 2305052-86-0 | 98.8% | C21H17ClN4O2 | 100 MG
BPK-25 is an active acrylamide that promotes the degradation of nucleosome remodeling and deacetylation (NuRD) complex proteins through a post-translational mechanism involving covalent protein engagement. It also inhibits TMEM173 activation by the cyclic dinucleotide ligand cGAMP.
- Promotes degradation of NuRD complex proteins.
- Inhibits TMEM173 activation.
- Active acrylamide.
- Intended for research and analytical applications.
![Medchemexpress LLC Ethyl 4'-((methyl(3-(pyridin-4-yl)benzyl)carbamoyl)oxy)-[1,1'-biphenyl]-4-carboxylate | 947669-86-5 | MFCD28160857 | 99.7% | 466.53 | C29H26N2O4 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000263530.png-250.jpg)
Medchemexpress LLC Ethyl 4'-((methyl(3-(pyridin-4-yl)benzyl)carbamoyl)oxy)-[1,1'-biphenyl]-4-carboxylate | 947669-86-5 | MFCD28160857 | 99.7% | 466.53 | C29H26N2O4 | 5 MG
WWL113 is a selective, orally active small-molecule inhibitor of carboxylesterases Ces3 and Ces1f used in biochemical and in vivo research to probe lipid metabolism and metabolic syndrome. It has shown efficacy in mouse models, improving lipid and glucose parameters after oral dosing.
- Selective Ces3 and Ces1f inhibitor with potent activity.
- Demonstrated in vivo efficacy in metabolic disease models.
- High purity suitable for research applications.
- Soluble in DMSO and formulatable for in vivo dosing protocols.
- Applicable to biochemical, cell-based, and animal studies.
eMolecules 1918125-85-5 | Ambeed | (4S5S)-2-(2-(Diphenylphosphanyl)phenyl)-45-diphenyl-45-dihydrooxazole | 100mg | 633660447 | A1352088 | 483.551 | C33H26NOP
Ambeed | (S)-2-Methylpiperidine | 1g | 552802083 | A714691 | 3197-42-0 | MFCD01862169 | 99.177 | C6H13N
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