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Filtered Search Results
eMolecules 20197-86-8 | ChemScene | 2-Chloro-67-dimethoxyquinazolin-4(3H)-one | 100mg | 718356728 | CS-0226197 | MFCD08458256 | 240.64 | C10H9ClN2O3
Ambeed | 5-Amino-1-(tert-butyl)-1H-pyrazol-3-ol | 250mg | 491641310 | A210752 | 359867-35-9 | MFCD14607822 | 155.201 | C7H13N3O
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eMolecules 864716-85-8 | Medchem Express | Mesendogen | 5mg | 784543571 | HY-103073 | MFCD03991832 | 400.84 | C18H16ClF3N2OS
Medchem Express | Mesendogen | 5mg | 784543571 | HY-103073 | 864716-85-8 | MFCD03991832 | 400.840 | C18H16ClF3N2OS
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Medchemexpress LLC 2-(3-oxo-1-phenyl-3-(4-(trifluoromethyl)phenyl)propyl)malonic acid | 1221962-86-2 | 98.0% | 10 MG
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PS210 is a small-molecule activator of PDK1 provided for research use. It binds the PIF-binding pocket of PDK1 and is supplied as a solid or as a 10 mM solution in DMSO for in vitro studies.
- Small-molecule PDK1 activator for research use.
- Solid and 10 mM DMSO solution formats available.
- High purity (~98.0%) confirmed by supplier analytical data.
- Molecular weight 380.31 g/mol; formula C19H15F3O5.
- Supplied in small milligram quantities suitable for biochemical assays.
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Medchemexpress LLC 1-(3-fluorophenyl)-5-methylpyridin-2(1H)-one | 848353-85-5 | 99.8% | 50 MG
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Fluorofenidone (AKF-PD) is an orally active small-molecule research compound with reported anti-fibrotic, antioxidant, and anti-inflammatory effects. Supplied as a purified analytical standard suitable for in vitro and in vivo studies and commonly provided as a 50 mg pack.
- Orally active small molecule with anti-fibrotic and anti-inflammatory activity.
- Demonstrated cellular effects (e.g., NIH/3T3 IC50 ~2.75 mM) and in vitro activity in lung and cancer cell lines.
- Shows protective effects in rodent models of lung injury, cholestasis, and fibrosis.
- High purity suitable for analytical and preclinical research applications.
- Molecular formula C12H10FNO; molecular weight 203.21 g/mol.
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Medchemexpress LLC KG5 | 877874-85-6 | C20H16F3N7OS | 100 MG
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KG5 is an orally active dual PDGFRβ and B-Raf allosteric inhibitor, also inhibiting Flt3, KIT, and c-Raf. It demonstrates anticancer and antiangiogenic activities.
- Inhibits vascular smooth muscle cells and endothelial cells viability
- Selectively blocks S338 phosphorylation
- Inhibits PDGFRα, PDGFRβ, Flt3, and KIT
- Prevents tumor growth in an orthotopic renal cell carcinoma model
- Completely blocks angiogenesis in mice
- Disrupts angiogenesis during zebrafish embryogenesis
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Medchemexpress LLC Rhodojaponin V | 37720-86-8 | MFCD01724481 | 1 MG
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Rhodojaponin V is a diterpenoid isolated from the leaves of *Rhododendron molle*. This compound exhibits anti-inflammatory activity and is identified as the C-14 acetylation product of Rhodojaponen III. It is intended for research use only.
- Diterpenoid compound
- Isolated from *Rhododendron molle*
- Exhibits anti-inflammatory activity
- C-14 acetylation product of Rhodojaponen III
- For research use only
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eMolecules 944904-85-2 | ChemScene | 1-(5-(Trifluoromethyl)pyridin-3-yl)ethanone | 100mg | 632294631 | CS-0155107 | MFCD10696266 | 189.137 | C8H6F3NO
ChemScene | 1-(5-(Trifluoromethyl)pyridin-3-yl)ethanone | 100mg | 632294631 | CS-0155107 | 944904-85-2 | MFCD10696266 | 189.137 | C8H6F3NO
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Medchemexpress LLC Nav1.1 activator 1 | 2332897-85-3 | 99.0% | 440.46 | 50 MG
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Nav1.1 activator 1 | 2332897-85-3 | 99.0% | 440.46 | 50 MG
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Medchemexpress LLC LYS006 | 100MG
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LYS006 | 100MG
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Medchemexpress LLC PR5-LL-CM01 | 1005307-86-7 | 98.4% | 401.51 | 50 MG
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PR5-LL-CM01 is a potent protein arginine methyltransferase 5 (PRMT5) inhibitor with an IC50 of 7.5 μM. It exhibits anti-tumor activities and demonstrates efficacy in inhibiting cancer cells while showing low toxicity in normal cells.
- Has IC50 values ranging from 2-4 μM in PDAC cells (PANC1, MiaPaCa2, and AsPC1) and 10-11 μM in CRC cells (HT29, HCT116, and DLD1).
- Strongly inhibits colony-forming ability in both PANC1 and HT29 cells.
- Inhibits NF-κB activation and its target gene expression in PDAC and CRC cells.
- Significantly decreases TNFα and IL8 expression in both PANC1 and HT29 cells (at 0-15 μM).
- Shows significant anti-tumor effects in PANC1 and HT29 xenografted mice in vivo (20 mg/kg; i.p.; 3 times per week) without visibly affecting their body weight.
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Medchemexpress LLC Catalposide | 6736-85-2 | 5 MG
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Catalposide is an iridoid glycoside isolated from Catalpa ovata G. Don (Bignoniaceae). It inhibits the production of TNF-α, IL-1β, and IL-6, and also suppresses NF-κB (p65) activation in lipopolysaccharide-activated RAW 264.7 macrophages. It is intended for research use only.
- Purity of 98.0%
- Inhibits TNF-α, IL-1β, and IL-6 production
- Suppresses NF-κB (p65) activation in lipopolysaccharide-activated RAW 264.7 macrophages
- Displays IC50 > 10 μM against human A2780, A549, BGC-823, Bel-7402, and HT-29 cells
- Isolated from Catalpa ovata G. Don (Bignoniaceae)
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eMolecules 126120-86-3 | 2,2-DIFLUOROBENZO[D][1,3]DIOXOL-4-OL | AstaTech | MFCD18451422 | 174.103 | C7H4F2O3 | 95.000 | Oc1cccc2OC(F)(F)Oc12 | 0.25g | 436051980
2,2-DIFLUOROBENZO[D][1,3]DIOXOL-4-OL | AstaTech | 126120-86-3 | MFCD18451422 | 174.103 | C7H4F2O3 | 95.000 | Oc1cccc2OC(F)(F)Oc12 | 0.25g | 436051980
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eMolecules 2374958-85-5 | Ambeed | (4S4S)-44-Diisopropyl-11-di-m-tolyl-4455-tetrahydro-1H1H-22-biimidazole | 100mg | 714083376 | A1501171 | 402.586 | C26H34N4
Pharmablock | 2-methoxy-4-methyl-1H-pyrimidin-6-one | 25mg | 784547466 | PBT8844 | 55996-28-6 | MFCD16988156 | 140.142 | C6H8N2O2
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eMolecules 1797409-86-9 | Ambeed | 2H-Pyrazolo[43-d]pyrimidin-7(6H)-one | 100mg | 714087621 | A651037 | MFCD28392134 | 136.114 | C5H4N4O
Ambeed | rel-Methyl (4aS7aS)-6-benzylhexahydropyrano[23-c]pyrrole-7a(2H)-carboxylate | 100mg | 672522902 | A1492658 | 2696257-57-3 | 550.696 | C32H42N2O6
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Medchemexpress LLC Sweroside | 14215-86-2 | 358.34 | 5 MG
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Sweroside | 14215-86-2 | 358.34 | 5 MG
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