Azolines
eMolecules 511240-22-5 | Methyl 3-amino-4-(isopropylamino)benzoate | MFCD01570644 | 1g
Combi-Blocks | Methyl 3-amino-4-(isopropylamino)benzoate | 1g | 205414519 | WZ-9016 | 96.000 | 511240-22-5 | MFCD01570644 | 208.261 | C11H16N2O2
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eMolecules Building Block Tool
Medchemexpress LLC M-PEG-thiol (MW 5000) | 88778-21-6 | 99.9% | 500 MG
M-PEG-thiol (MW 5000) is a PEG-based PROTAC linker employed in the synthesis of PROTACs. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting two different ligands: one for an E3 ubiquitin ligase and the other for the target protein.
- Utilized as a PEG-based PROTAC linker
- Supports the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Enables selective degradation of target proteins
Medchemexpress LLC Thiol-PEG5-thiol | 89141-22-0 | 1 G
Thiol-PEG5-thiol (Bis-PEG5-thiol) is a bifunctional thiol cross-linker agent.
- Molecular formula: C₁₂H₂₆O₅S₂
- Molecular weight: 314.46
- Target: Biochemical assay reagents
Medchemexpress LLC Thiol-PEG4-acid | 749247-06-1 | 95.0% | 25 MG
Thiol-PEG4-acid is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. These compounds consist of two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other targeting a protein for degradation. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Purity of 95.0%
- Molecular weight: 282.35
- Chemical formula: C11H22O6S
- Appearance: colorless to light yellow liquid
- Storage at 4°C under nitrogen
- In solvent, store at -80°C for 6 months or -20°C for 1 month under nitrogen
- Density: 1.156±0.06 g/cm3
Apexbio Technology LLC Methimazole 60-56-0 10mM (in 1mL DMSO)
Methimazole is a small-molecule inhibitor targeting intercellular adhesion molecule-1 (ICAM-1) gene transcription It is designed to modulate ICAM-1 expression thereby regulating cell adhesion processes mediated by immunoglobulin superfamily members and integrins such as LFA-1 and Mac-1 Methimazole exerts its biological activity primarily through modulation of signal transducer and activator of transcription 1 (STAT1) In cell-based studies using thyroid cell models methimazole demonstrates inhibitory activity suppressing ICAM-1 mRNA expression induced by interferon-gamma (IFN- ) and H O Based on these pharmacological properties methimazole holds research potential in studying autoimmune thyroid conditions and as an agent to induce hypothyroidism in animal models for thyroid dysfunction research
Sigma Aldrich Fine Chemicals Biosciences RO-3306 >=98% (HPLC) | 872573-93-8 | MFCD17392573 | 25MG
RO-3306 >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 351.45 | 872573-93-8 | MFCD17392573 | 25MG
Medchemexpress LLC M-PEG-thiol (MW 2000) | 134874-49-0 | 99.8% | COCCOCCS.[MW 2000].[n] | 50 MG
M-PEG-thiol (MW 2000) is a PEG-based PROTAC linker used in the synthesis of PROTACs. These molecules feature two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other for the target protein. PROTACs harness the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Sigma Aldrich Fine Chemicals Biosciences RO-3306 | 872573-93-8 | MFCD17392573 | 5mg
RO-3306 | Purity: 98% | Mol Wt: 351.45 | 872573-93-8 | MFCD17392573 | 5mg
Medchemexpress LLC L-homocysteine thiolactone hydrochloride | 31828-68-9 | MFCD00065494 | 100.0% | 153.63 g·mol⁻¹ | C4H8ClNOS | 25 MG
L-Homocysteine thiolactone hydrochloride is the intramolecular thioester of homocysteine supplied as a research reagent. It functions as an amine-reactive compound used to probe homocysteine metabolism and protein post-translational modification in biochemical and cellular studies.
- Acts as an amine-reactive agent that can modify lysine residues.
- Used to study homocysteine metabolism and protein incorporation.
- Molecular formula: C4H8ClNOS; molecular weight: 153.63 g·mol⁻¹.
- CAS number: 31828-68-9.
- High stated purity (≈99.99%).
- Available in small pack sizes such as 25 mg for laboratory use.
Medchemexpress LLC Thiol-PEG-acetic acid (SH-PEG-COOH) | 00-00-0 | 95.0% | HSC2H4O(C2H4O)nCH2CO2H | 10MG
Thiol-PEG-CH2COOH (MW 5000) is a heterobifunctional polyethylene glycol linker bearing a thiol at one terminus and a carboxylic acid at the other. It provides a flexible spacer for PROTAC assembly and other bioconjugation workflows, enabling orthogonal attachment strategies while maintaining solubility and spacer length control.
Selleck Chemical LLC Serotonin (5-HT) HCl S4244-1g
Serotonin (5-HT) HCl is a monoamine neurotransmitter and Endogenous 5-HT receptor agonist