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Omeprazole Sodium (CAS No 95510-70-6) is a proton pump inhibitor used extensively in biomedical research due to its ability to reduce gastric acid secretion by inhibiting the H /K ATPase enzyme in the stomach lining Originating from the benzimidazole class it is crucial in studies focusing on gastrointestinal and digestive health Its mechanism of action disrupts the final step of gastric acid production making it effective in vitro with activity commonly observed in the nanomolar to low micromolar range This compound is frequently employed in cell models and animal studies for drug screening and investigating potential therapeutic interventions for gastric acid-related disorders Experimental concentrations typically depend on the specific research design ensuring flexibility in various study contexts Researchers utilize its properties to explore treatment options for conditions such as ulcers and reflux disease contributing to advancements in gastroenterology
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(R)-Omeprazole sodium is a gastric acid resistant compound that inhibits gastric acid secretion. It is primarily metabolized in vivo by cytochrome P450 enzymes. Interactions with mannitol may affect its bioavailability in certain formulations.
Inhibits gastric acid secretion
Metabolized by cytochrome P450 enzymes
Interacts with mannitol
Reversibly inhibits CYP2C19 directly and metabolism-dependently
For research use only
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An active metabolite of omeprazole; has been used as a precursor in the synthesis of esomeprazole; a potential impurity in commercial preparations of omeprazole
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(R)-Omeprazole sodium is a gastric acid resistant compound that inhibits gastric acid secretion. Its metabolism in vivo is primarily affected by cytochrome P450 enzymes. The interaction between (R)-Omeprazole sodium and mannitol may affect its bioavailability in formulations. It exhibits reversible direct and metabolism-dependent inhibition of CYP2C19.
Gastric acid resistant compound
Inhibits gastric acid secretion
Metabolized primarily by cytochrome P450 enzymes
Interaction with mannitol may affect bioavailability
Exhibits reversible direct and metabolism-dependent inhibition of CYP2C19
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Also available in 1 mL, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic. Purity 98.04%
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An active metabolite of albendazole; inhibits spore formation of E. hellem, E. cuniculi, and E. intestinalis in vitro (IC90s = <0.0001, <0.001, and <0.1 µg/ml, respectively)
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MW 265.33 Da, Purity >98%. Anthelmintic benzimidazole and microtubule depolymerizing agent. Able to inhibit brain microtubule polymerization in vitro and delays microtubule assembly in vivo. Anti-tumour activity seen in vivo.