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(R)-Omeprazole sodium is a gastric acid resistant compound that inhibits gastric acid secretion. It is metabolized in vivo, primarily by cytochrome P450 enzymes, and its interaction with mannitol may affect its bioavailability in formulations. It exhibits reversible direct and metabolism-dependent inhibition of CYP2C19.
Gastric acid resistant compound
Inhibits gastric acid secretion
Metabolized by cytochrome P450 enzymes
Reversible direct and metabolism-dependent inhibition of CYP2C19
For research use only
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Omeprazole sulfide-d3 is the deuterium-labeled analogue of omeprazole sulfide, a metabolite of the proton-pump inhibitor omeprazole. It is provided as an isotopically labeled reference standard intended for use as a tracer and an internal standard in quantitative analytical workflows to support accurate identification and measurement.
Deuterium-labeled internal standard for quantitative analysis.
Suitable for NMR, GC-MS, and LC-MS applications.
High purity (99.79% by LCMS) for reliable assay performance.
Molecular weight 332.44 and formula C17H16D3N3O2S for unambiguous identification.
Available in solid and solution formats for flexible use.
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Omeprazole sulfide-d3 is the deuterium-labeled analogue of omeprazole sulfide, supplied as a stable isotope reference standard for analytical and metabolic studies. It is intended for use as an internal standard in quantitative mass spectrometry and pharmacokinetic investigations.
Deuterium-labeled internal standard for LC-MS quantitation.
High purity (99.8%).
Suitable for metabolic and pharmacokinetic studies.
Small package sizes convenient for analytical workflows.
Stable as a powder at -20 °C for long-term storage; follow solvent storage recommendations.
Handling notes: hygroscopic DMSO affects solubility; aliquot and avoid repeated freeze-thaw.
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Omeprazole-d3 is a deuterium-labeled omeprazole supplied as a stable-isotope reference standard for analytical and research applications, especially as an internal standard in LC-MS, pharmacokinetic, and metabolic studies. It is provided as a light brown solid with high chemical purity suitable for quantitative analysis.
Deuterium-labeled internal standard for LC-MS quantitation.
High chemical purity (≈99.0%) suitable for analytical applications.
Solid form with light brown to brown appearance for easy handling.
Includes CAS number 922731-01-9 for unambiguous identification.
Stable when stored as powder at -20°C for up to 3 years.
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Omeprazole sodium is a proton pump inhibitor (PPI) used in the treatment of acid-related gastrointestinal disorders. It competitively inhibits CYP2C19 activity with a Ki of 2 to 6 μM. It also inhibits the growth of both Gram-positive and Gram-negative bacteria, and is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor).
Proton pump inhibitor (PPI)
Treats acid-related gastrointestinal disorders
Competitively inhibits CYP2C19 activity with a Ki of 2 to 6 μM
Inhibits growth of Gram-positive and Gram-negative bacteria
An active metabolite of omeprazole; has been used as a precursor in the synthesis of esomeprazole; a potential impurity in commercial preparations of omeprazole
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