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Aromatic organic heterocyclic compounds that consist of benzene fused with a diazepine ring; diazepine rings are seven-membered heterocyclic compounds with two nitrogen atoms.
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Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase Renilla luciferase and substrate coelenterazine have been used as bioluminescence donors in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions Coelenterazine is a superoxide anion-sensitive chemiluminescent probe and it can also be used in the chemiluminescent detection of peroxynitrite
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Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Clozapine Analogues can be used to study neurological disorders. Purity 99.6%
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase Renilla luciferase and substrate coelenterazine have been used as bioluminescence donors in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions Coelenterazine is a superoxide anion-sensitive chemiluminescent probe and it can also be used in the chemiluminescent detection of peroxynitrite
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Clozapine N-oxide is a major metabolite of clozapine and a human muscarinic designer receptors (DREADDs) agonist. It activates the DREADD receptor hM3Dq and hM4Di but cannot cross the blood-brain barrier. Its parent compound, clozapine, is a potent dopamine antagonist and a potent and selective muscarinic M4 receptor agonist. For research use only.
DREADD activator
Metabolite of clozapine
Activates hM3Dq and hM4Di DREADD receptors
Cannot cross the blood-brain barrier
Solid appearance, light yellow to yellow color
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase Renilla luciferase and substrate coelenterazine have been used as bioluminescence donors in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions Coelenterazine is a superoxide anion-sensitive chemiluminescent probe and it can also be used in the chemiluminescent detection of peroxynitrite
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. It has been used as the bioluminescence donor in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions. This compound is also a superoxide anion-sensitive chemiluminescent probe and can be used in chemiluminescent detection of peroxynitrite (Ex/Em = 429/466 nm).
Luminescent enzyme substrate for apoaequorin and Renilla luciferase.
Used as a bioluminescence donor in BRET to detect protein-protein interactions.