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Benzoxadiazoles

Organic heterocyclic compounds that consist of benzene fused with an oxadiazole; oxadiazoles are a five-membered ring with two carbon atoms, one oxygen atom, and two nitrogen atoms.

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1

AdipoGen NBD dodecanoic acid N-SE
SDP

Chemical. CAS 689263-76-1. Formula C22H29N5O7. MW 475.5. Synthetic. Suitable for probing the ligand binding sites of fatty acid and sterol carrier proteins as well as the investigation of lipolysis processes.

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2

Medchemexpress LLC NBD-amine | 10199-91-4 | 96.7% | 50 MG
SDP

NBD-amine is a fluorogenic amine used as a fluorescent probe and reagent. It fluoresces weakly in water and strongly in organic solvents, membranes, and other hydrophobic environments, and is supplied as a powder with demonstrated solubility in DMSO.

  • Fluorogenic amine that increases fluorescence in hydrophobic environments.
  • CAS number 10199-91-4; molecular weight 180.12 g·mol⁻¹; formula C6H4N4O3.
  • Purity 96.7% as supplied.
  • Soluble in DMSO (≈31.25 mg/mL); hygroscopic DMSO affects solubility.
  • Storage: powder -20°C (stable up to 3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
  • Available in multiple package sizes including 50 MG.

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3

Medchemexpress LLC 7-Fluorobenzofurazan-4-sulfonic acid ammonium | 84806-27-9 | 98.96% | 50 MG
SDP

7-Fluorobenzofurazan-4-sulfonic acid ammonium is a fluorescent label that can be utilized for detecting dissolved thiol-disulfide, such as Cys and GSH. It is intended for research use only and not for patient use.

  • Fluorescent label: can be used for detecting dissolved thiol-disulfide (e.g., Cys, GSH).
  • Purity: 98.96%.
  • Appearance: solid.
  • Color: light yellow to yellow.
  • Emission (Em): 495.
  • Excitation (Ex): 478.
  • Solubility: soluble in DMSO (250 mg/mL) and H2O (≥ 50 mg/mL).
  • Storage: 4°C, sealed storage, away from moisture and light. In solvent: -80°C for 6 months; -20°C for 1 month (sealed storage, away from moisture and light).

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4

Medchemexpress LLC Nbd-14270 | 2411819-82-2 | 99.5% | 425.43 | C18H18F3N5O2S | 5 MG
SDP

NBD-14270 is a pyridine analogue that functions as a potent HIV-1 entry antagonist by binding to the gp120 envelope protein. It exhibits sub-micromolar antiviral activity with low cytotoxicity and is provided for research applications with characterized purity, formula, and storage recommendations.

  • High purity: 99.53%.
  • Chemical formula: C18H18F3N5O2S; molecular weight: 425.43.
  • CAS number: 2411819-82-2.
  • Recommended solvent: DMSO; use ultrasonic aid for dissolution.
  • Storage: solid at 4°C; in solvent store at -80°C for long-term stability.
  • Typical applications: in vitro antiviral and HIV-1 entry assays.

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5

Medchemexpress LLC 6alpha-ethyl-3alpha,7alpha,23-trihydroxy-24-nor-5beta-cholan-23-sulfate sodium salt | 1000403-03-1 | 99.8% | 494.66 g/mol | C25H43NaO6S | 10MM 1ML
SDP

INT-767 is a research-grade dual farnesoid X receptor (FXR) and TGR5 agonist with reported mean EC50 values of 30 nM (FXR) and 630 nM (TGR5). It is supplied as a white to off-white solid and is available as a 10 mM solution in DMSO. Molecular formula C25H43NaO6S; molecular weight 494.66 g/mol. Intended for laboratory research use only.

  • Potent dual FXR and TGR5 agonist with EC50s of 30 nM and 630 nM, respectively.
  • High purity suitable for research applications.
  • Available as solid or 10 mM DMSO solution for convenience.
  • Highly soluble in DMSO and water according to manufacturer data.
  • Stable under recommended storage: solid at 4°C; in solution at -80°C for long-term storage.
  • Used in studies of bile acid signaling, metabolic disease, and liver injury models.

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6

Medchemexpress LLC NBD-14189 | 2234273-72-2 | 99.8% | C18H16F4N4O2S | 10MG
SDP

NBD-14189 is a small-molecule HIV-1 entry antagonist that binds the viral gp120 envelope protein and blocks virus entry. It shows potent activity in cell-based assays (IC50 ≈ 89 nM against HIV-1 HXB2 pseudovirus; antiviral EC50 <200 nM) and is supplied as a high-purity research compound for in vitro studies.

  • Potent gp120-directed entry antagonist with IC50 ≈ 89 nM.
  • Demonstrated antiviral activity in cell assays (EC50 <200 nM).
  • High purity suitable for research use (≈99.8%).
  • Supplied as solid and as 10 mM solution in DMSO for screening.
  • Molecular formula C18H16F4N4O2S and molecular weight 428.40 g·mol⁻1.
  • Recommended storage: 4°C sealed; in solvent store at -80°C for long term.

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