Biotin and derivatives
Medchemexpress LLC FP-biotin | 259270-28-5 | 99.8% | C27H50FN4O5PS | 10MG
FP-Biotin is a biotinylated fluorophosphonate probe designed to covalently label serine hydrolases for activity-based profiling. The biotin tag enables enrichment and identification of labeled proteins or peptides from plasma and complex samples using avidin/streptavidin capture. Available as a solid and as a DMSO solution for flexible workflows.
- covalently labels serine hydrolases for activity profiling
- enables affinity purification via biotin-avidin interaction
- suitable for plasma and complex biological samples
- supplied as solid or ready-to-use solution for workflow flexibility
- high purity for reproducible results
- supported by data sheet, COA, and SDS for quality and safety
Medchemexpress LLC Alexa fluor 647 NHS ester | 1620475-28-6 | 95.0% | 942.06 g/mol | C39H47N3O16S4 | 10 MG
Alexa Fluor 647 NHS ester is a far-red, amine-reactive fluorescent dye (succinimidyl ester) used to covalently label primary amines on proteins, peptides, and amine-modified oligonucleotides for fluorescence imaging and flow cytometry.
- Far-red, bright, and photostable fluorescent dye suitable for imaging and flow cytometry.
- Amine-reactive NHS (succinimidyl) ester enables covalent labeling of primary amines.
- Compatible with proteins, peptides, and amine-modified oligonucleotides.
- High purity (95.0%) for reliable conjugation performance.
- Supplied as a solid; store sealed at -20°C, protected from moisture and light.
- COA, SDS, and handling documents available to support safe use and quality verification.
Medchemexpress LLC m-PEG24-NHS ester | 2395839-96-8 | 99.7% | 25 MG
m-PEG24-NHS ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These compounds harness the intracellular ubiquitin-proteasome system to selectively degrade target proteins, offering a novel approach in therapeutic development. This product is intended for research use only and is supplied as a white to off-white solid.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
- Stable under recommended storage conditions
Medchemexpress LLC NOTA-NHS ester | 1338231-09-6 | MFCD30747764 | ≥97.0% | 400.38 g/mol | C16H24N4O8 | 25 MG
NOTA-NHS ester is a bifunctional chelator derivative used for fluorescent labeling and radiolabeling (radionuclide-drug conjugates). It contains an activated N-hydroxysuccinimide (NHS) ester for conjugation to primary amines and a NOTA chelator for radiometal coordination. Supplied for research use only.
- Activated N-hydroxysuccinimide (NHS) ester for conjugation to primary amines.
- NOTA chelator for stable binding of radiometals.
- Purity ≥97.0%.
- CAS number 1338231-09-6.
- Molecular formula C16H24N4O8; molecular weight 400.38 g/mol.
- Recommended storage: powder -20°C; in solvent -80°C (6 months) or -20°C (1 month).
eMolecules 58-85-5 | D-(+)-Biotin | Apollo Scientific US | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 5g | 870070951
D-(+)-Biotin | Apollo Scientific US | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 5g | 870070951
eMolecules 58-85-5 | D-(+)-Biotin | Apollo Scientific | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 1g | 562432212
D-(+)-Biotin | Apollo Scientific | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 1g | 562432212
![eMolecules 58-85-5 | Biotin | Ambeed | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 10g | 518521733](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000169626.jpg-250.jpg)
eMolecules 58-85-5 | Biotin | Ambeed | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 10g | 518521733
Biotin | Ambeed | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 10g | 518521733
Medchemexpress LLC DBCO-NHCO-S-S-NHS ester | 96.0% | 565.66 | C28H27N3O6S2 | 25 MG
DBCO-NHCO-S-S-NHS ester is a cleavable antibody-drug conjugate (ADC) linker and click-chemistry reagent containing a DBCO moiety. It is designed to couple to amines via the NHS ester and to react with azide-bearing molecules through strain-promoted alkyne-azide cycloaddition (SPAAC); the disulfide (S-S) bond provides a reducible, cleavable linker for payload release.
- cleavable disulfide linker for reductive release
- n-hydroxysuccinimide (nhs) ester for amine coupling
- dbco group enables copper-free spaac click chemistry with azides
- solid, white to off-white appearance for easy handling
- available in small research pack sizes (including 25 mg)
- storage: powder at -20°C; in solvent stability at -80°C (6 months) or -20°C (1 month)
Medchemexpress LLC Propanoic acid, 3-(2-azidoethoxy)-, 2,5-dioxo-1-pyrrolidinyl ester | 1807530-06-8 | 99.8% | C9H12N4O5 | 50 MG
Azido-PEG1-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules. It can also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an azide group
- Facilitates copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc)
- Engages in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Suitable for use with molecules containing alkyne, DBCO, or BCN groups
- Enables selective degradation of target proteins
Apexbio Technology LLC NHS-SS-11-Biotin(Synonyms: Sulfo-NHS-SS-Biotin, EZ-Link NHS-SS-Biotin, NHS-SS-D-Biotin, N-Hydroxysuccinimidyl-SS-Biotin), 50mg, CAS: 142439-92-7.
NHS-SS-11-Biotin (CAS 142439-92-7) is an amine-reactive biotinylation reagent commonly used in biochemical research Structurally it possesses an N-hydroxysuccinimide (NHS) ester group that covalently reacts with primary amines of target proteins or biomolecules forming stable amide bonds and releasing sulfo-NHS This reagent features a cleavable disulfide linker and an extended spacer arm of approximately 24 3 enhancing probe accessibility to avidin or streptavidin conjugates It is utilized extensively for reversible biotinylation affinity purification or labeling studies in proteomics and cell biology applications
Apexbio Technology LLC Sulfo-NHS-LC-D-Desthiobiotin 5X1mg
Sulfo-NHS-LC-D-Desthiobiotin is a sulfonated amine-reactive labeling reagent targeting primary amines on proteins or peptides It is designed to covalently label cell-surface proteins by reacting with lysine residues or protein N-termini thereby enabling selective modification of these proteins Sulfo-NHS-LC-D-Desthiobiotin exerts its biological activity primarily through covalent reaction with primary amines via its activated Sulfo-NHS ester Due to its membrane-impermeable negatively charged sulfonate group it selectively labels cell-surface proteins without entering intact cells Based on these chemical properties Sulfo-NHS-LC-D-Desthiobiotin holds research potential in affinity purification biotin-streptavidin interaction assays selective enrichment and analytical workflows involving reversible labeling of surface proteins
Medchemexpress LLC Biotin-lc-lc-nhs | 89889-52-1 | 98.0% | 567.70 | C26H41N5O7S | 25 MG
Biotin-LC-LC-NHS is an N-hydroxysuccinimide (NHS) ester biotinylation reagent with dual long-chain spacers. It covalently attaches biotin to primary amines on proteins, antibodies, and small molecules for labeling, detection, or affinity capture. Handle using appropriate safety precautions and store protected from light at -20°C.
- NHS ester reactive toward primary amines.
- Dual long-chain spacers reduce steric hindrance during labeling.
- Molecular weight 567.70 and formula C26H41N5O7S for precise calculations.
- Purity 98.0% for research-grade applications.
- High solubility in DMSO (100 mg/mL) with recommended freshly opened DMSO.
- Store at -20°C, protect from light, and handle under standard laboratory safety practices.
Medchemexpress LLC DBCO-NHS ester 2 100mg | 1384870-47-6 | 100 MG
DBCO-C6-NHS ester is a DBCO-derived N-hydroxysuccinimide (NHS) ester used to introduce a DBCO handle onto amine-containing molecules for copper-free, strain-promoted alkyne-azide cycloaddition (SPAAC) bioconjugation and antibody-drug conjugate (ADC) linker synthesis.
- Amine-reactive NHS ester for covalent coupling to primary and secondary amines.
- Facilitates copper-free SPAAC click chemistry with azide-functionalized partners.
- Suitable for bioconjugation, ADC synthesis, and labeling of proteins or small molecules.
- Available in multiple sizes; typical laboratory scale is 100 mg.
- Soluble in DMSO (~14.29 mg/mL); store powder at -20°C for long-term stability.