Biotin and derivatives
Medchemexpress LLC DBCO-NHS ester | 1353016-71-3 | 99.1% | 402.40 g·mol⁻1 | C23H18N2O5 | 5 MG
DBCO-NHS ester is a dibenzocyclooctyne-derived N-hydroxysuccinimide (NHS) ester for copper-free click bioconjugation via strain-promoted alkyne-azide cycloaddition (SPAAC). It is used to install linkers and conjugate azide-bearing molecules in chemical biology and antibody-drug conjugate (ADC) workflows.
- Enables copper-free SPAAC with azide-containing molecules.
- Suitable for linker installation and bioconjugation in ADC and biomolecule conjugation workflows.
- Reported high purity for analytical and preparative use.
- Available in small research quantities, including 5 MG format.
Medchemexpress LLC Biotin-Val-Ala-Asp(OMe)-FMK | 1135688-15-1 | ≥95.0% | 672.81 g/mol | C30H49FN6O8S | 50 MG
Biotin-VAD-FMK is a biotin-labeled, cell-permeable, irreversible pan-caspase inhibitor used to identify and label active caspases in cell lysates. It serves as an affinity probe for detection or capture of active caspases in apoptosis research and protease-profiling workflows, and is compatible with biochemical assays and pull-down experiments.
- Biotin-labeled for affinity capture and detection.
- Cell-permeable, irreversible caspase inhibitor.
- Enables identification and labeling of active caspases in cell lysates.
- Compatible with biochemical assays, protease profiling, and pull-down workflows.
- Supplied as a solid with defined molecular weight and formula for experimental planning.
Sigma Aldrich Fine Chemicals Biosciences Biotin meets USP testing specifications | 58-85-5 | MFCD00005541 | 500MG
Biotin meets USP testing specifications | Purity: 97.5-102.0% | Mol Wt: 244.31 | 58-85-5 | MFCD00005541 | 500MG
Sigma Aldrich Fine Chemicals Biosciences Biotin >=99% (HPLC), lyophilized powder | 58-85-5 | MFCD00005541 | 25G
Biotin >=99% (HPLC), lyophilized powder | Purity: >=99% (HPLC) | Mol Wt: 244.31 | 58-85-5 | MFCD00005541 | 25G
Medchemexpress LLC N3-peg3-c2-nhs ester | 1245718-89-1 | MFCD23726613 | 99.9% | 344.32 g/mol | C13H20N4O7 | 10 G
Azide-terminated PEG3 NHS ester linker for bioconjugation and click-chemistry labeling. The reagent contains an azide group for copper-catalyzed azide-alkyne cycloaddition (CuAAC) and is compatible with strain-promoted alkyne-azide cycloaddition (SPAAC). It is supplied as a high-purity NHS ester for amine conjugation and includes a three-unit PEG spacer to improve solubility and reduce steric hindrance.
- Azide functional group for click chemistry reactions.
- NHS ester for efficient conjugation to primary amines.
- Three-unit PEG spacer to enhance solubility.
- Noncleavable linker for stable conjugation.
- High purity suitable for research applications.
- Available in laboratory-scale 10 g packaging.
Medchemexpress LLC DBCO-PEG3-NHS ester | 2163772-16-3 | 98.5% | 605.64 g/mol | C32H35N3O9 | 10 MG
DBCO-PEG3-NHS ester is a PEG-spaced dibenzocyclooctyne (DBCO) reagent bearing an N-hydroxysuccinimide (NHS) ester. It is designed for copper-free click conjugation of azide-functionalized payloads to primary amines and is commonly used as a linker in bioconjugation workflows such as antibody-drug conjugate synthesis.
- Enables copper-free strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing partners.
- Contains an NHS ester reactive toward primary amines for facile conjugation.
- Peg3 spacer improves solubility and reduces steric hindrance at the conjugation site.
- Suitable for bioconjugation workflows, including linker installation for antibody-drug conjugates.
- Provided at high reported purity for reproducible conjugation performance.
Medchemexpress LLC Sulfo-NHS-LC-LC-biotin | 194041-66-2 | 99.3% | 669.74 g/mol | C26H40N5NaO10S2 | 10 MG
Sulfo-NHS-LC-LC-Biotin is a water-soluble, amine-reactive biotinylation reagent that contains a sulfo-NHS ester joined to biotin via a long-chain spacer arm to reduce steric hindrance and improve labeling efficiency. It reacts selectively with primary amines to form stable amide bonds and is commonly used to label proteins on intact exosomes and cell surfaces.
- Water soluble sulfo-NHS ester for aqueous labeling.
- Long-chain spacer reduces steric hindrance and improves accessibility.
- Reacts selectively with primary amines to form stable amide bonds.
- Suitable for labeling proteins on intact exosomes and crowded surfaces.
- Provided as a small-quantity powder for convenient handling in research workflows.
Medchemexpress LLC Biotin methyl ester 500mg
Biotin methyl ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research
Sigma Aldrich Fine Chemicals Biosciences Biotin >=99.0% (T) | 58-85-5 | MFCD00005541 | 100MG
Biotin >=99.0% (T) | Purity: >=99.0% (T) | Mol Wt: 244.31 | 58-85-5 | MFCD00005541 | 100MG