Biotin and derivatives
Medchemexpress LLC NHS-SS-biotin | 122266-55-1 | MFCD28505564 | 98.0% | 504.64 g/mol | C19H28N4O6S3 | 100 MG
NHS-SS-biotin is a cleavable disulfide-containing biotin linker with an N-hydroxysuccinimide (NHS) ester reactive group. It is used to introduce a biotin tag onto primary amines and as a reducible linker in antibody-drug conjugate synthesis and other bioconjugation workflows.
- Cleavable disulfide linker for reductive release.
- NHS ester reactive toward primary amines.
- Useful for protein and peptide biotinylation and affinity capture.
- Available in small-scale quantities suitable for research applications.
- Purity typically 98.0% as provided in supplier documentation.
Medchemexpress LLC L-biotin (unnatural enantiomer of biotin) | 21788-37-4 | MFCD22373639 | 99.5% | 244.31 g·mol⁻¹ | C10H16N2O3S | 1 ML
L-biotin is the unnatural enantiomer of biotin supplied as a research reagent. It binds streptavidin in vitro and is provided as a ready-to-use 10 mM solution in DMSO (1 mL) or as solid powder in multiple pack sizes. Recommended storage conditions are -20°C for powder, and -80°C for stock solutions (up to 6 months).
- Unnatural enantiomer of biotin
- Binds streptavidin in vitro
- Available as 10 mM DMSO solution or solid powder
- High purity (>99%)
- Soluble in DMSO at high concentration
- Powder storage: -20°C; stock solution storage: -80°C (6 months)
Medchemexpress LLC Recombinant human IGF2R protein, biotinylated | 50UG
Biotinylated recombinant human IGF2R protein (E47-M1508) is supplied as a lyophilized HEK293-expressed construct with C-terminal His and Avi tags for affinity purification and site-specific biotinylation. The product is intended for research on receptor-ligand interactions, intracellular trafficking, and related biochemical assays.
- Biotinylated recombinant protein suitable for ligand binding and trafficking studies.
- C-terminal His and Avi tags enable affinity purification and site-specific biotinylation.
- Expressed in mammalian HEK293 cells to preserve native glycosylation.
- Construct spans E47-M1508, covering relevant extracellular domains.
- Glycosylated protein with an apparent molecular weight of approximately 165-200 kDa.
- Lyophilized formulation with protectant; endotoxin level <1 EU/μg and recommended storage at -20°C.
Medchemexpress LLC NOTA-NHS ester | 1338231-09-6 | MFCD30747764 | ≥97.0% | 400.38 g/mol | C16H24N4O8 | 25 MG
NOTA-NHS ester is a bifunctional chelator derivative used for fluorescent labeling and radiolabeling (radionuclide-drug conjugates). It contains an activated N-hydroxysuccinimide (NHS) ester for conjugation to primary amines and a NOTA chelator for radiometal coordination. Supplied for research use only.
- Activated N-hydroxysuccinimide (NHS) ester for conjugation to primary amines.
- NOTA chelator for stable binding of radiometals.
- Purity ≥97.0%.
- CAS number 1338231-09-6.
- Molecular formula C16H24N4O8; molecular weight 400.38 g/mol.
- Recommended storage: powder -20°C; in solvent -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC L-biotin | 21788-37-4 | 99.7% | 244.31 | C10H16N2O3S | 25 MG
L-biotin is the unnatural enantiomer of biotin and is used as a biochemical research reagent. It is provided as a white to off-white solid with reported high purity and has been observed to bind streptavidin in laboratory assays.
- High purity suitable for research applications.
- White to off-white solid, easy to handle and store.
- Soluble in DMSO at high concentration for in vitro use.
- Available in small solid quantities appropriate for bench-scale experiments.
- Stable when stored frozen as a powder to extend shelf life.
Medchemexpress LLC DOTA-NHS-ester | 170908-81-3 | >97.0% | 501.49 g/mol | C20H31N5O10 | 250 MG
DOTA-NHS-ester is an NHS-activated DOTA chelator used to conjugate the DOTA moiety to biomolecules (for example, peptides, proteins, and affibodies) to enable radiolabeling for PET, SPECT, and radiotherapeutic research. It is supplied as a white to off-white solid with high purity and is soluble in DMSO.
- NHS-activated DOTA chelator for amine conjugation.
- High purity (>97.0%).
- Molecular weight 501.49 g/mol; formula C20H31N5O10.
- Soluble in DMSO (50 mg/mL); ultrasonic assistance recommended.
- Storage: sealed, away from moisture; in solvent -80°C (6 months) or -20°C (1 month).
- Intended for radiolabeling research (PET/SPECT); not for human use.
Apexbio Technology LLC Concanavalin A (Con A)-Biotin 5mg(5 mg/mL)
Concanavalin A (Con A) is a lectin protein derived from Canavalia ensiformis (jack bean) with a molecular weight of approximately 104 kDa Each subunit can bind one Ca2 and one Mn2 ion and contains a carbohydrate-binding site Upon binding these metal ions Con A specifically binds to glycoproteins glycolipids and carbohydrates containing -D-glucose and -D-mannose residues Biotin is a small-molecule water-soluble vitamin that exhibits very strong affinity to avidin Concanavalin A-Biotin is a labeled protein conjugate composed of Concanavalin A linked to biotin widely used in biological research especially for detecting and quantifying biomolecules containing specific carbohydrate structures through immunohistochemistry (IHC) immunocytochemistry (ICC) and enzyme-linked immunosorbent assay (ELISA)