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Biotin and derivatives

Organic heterocyclic compounds and derivatives that consist of a ureido ring and a tetrahydrothiophene ring; ureido contains the radical: NH2CONH−, and tetrahydrothiophene is a five-membered ring consisting of four carbon atoms and a sulfur atom.
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1,171 – 1,185 of 1,263 results
1,171

Medchemexpress LLC (+)-Biotin-SLC | 1864003-57-5 | ≥97.0% | 250 MG
SDP

(+)-Biotin-SLC is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

  • Alkyl chain-based PROTAC linker
  • Used in the synthesis of PROTACs
  • PROTACs contain two ligands (E3 ubiquitin ligase and target protein) connected by a linker
  • Exploits intracellular ubiquitin-proteasome system for target protein degradation
  • For research use only
  • Appearance: Solid
  • Color: White to off-white
  • Storage: 4°C under nitrogen; in solvent: -80°C (6 months) or -20°C (1 month) under nitrogen

ENCOMPASS_PREFERRED
1,172

Medchemexpress LLC 1H-thieno[3,4-d]imidazole-4-pentanamide, N-(26-azido-3,6,9,12,15,18,21,24-octaoxahexacos-1-yl) | 2363756-34-5 | 98.8% | 664.81 g/mol | C28H52N6O10S | 100 MG
SDP

Biotin-PEG8-azide is a biotin-labeled polyethylene glycol (PEG8) linker with a terminal azide group used for biotinylation of macromolecules via azide-alkyne cycloaddition (click chemistry). It enables efficient conjugation for affinity capture, detection, or immobilization in biochemical assays.

  • Provides a PEG8 spacer to improve solubility and reduce steric hindrance.
  • Contains a terminal azide for copper-catalyzed or strain-promoted click reactions.
  • Facilitates biotin labeling for high-affinity capture with streptavidin or avidin reagents.
  • High purity (98.8%) suitable for research applications.
  • Off-white to light yellow oil with storage recommendations for long-term stability.

ENCOMPASS_PREFERRED
1,173

Medchemexpress LLC Aeide-C1-NHS ester | 824426-32-6 | 98.0% | C6H6N4O4 | 250 MG
SDP

Aeide-C1-NHS ester | 824426-32-6 | 98.0% | C6H6N4O4 | 250 MG

ENCOMPASS_PREFERRED
1,174

Medchemexpress LLC m-PEG11-acid | 2280998-74-3 | 98.0% | 544.63 | C24H48O13 | 100 MG
SDP

m-PEG11-acid is a monomethyl-capped polyethylene glycol (PEG) linker containing 11 ethylene glycol units. It is supplied as a non-cleavable, hydrophilic spacer for use in antibody-drug conjugate (ADC) synthesis and proteolysis-targeting chimera (PROTAC) linker construction.

  • Monomethyl-capped polyethylene glycol linker with 11 ethylene glycol units.
  • Non-cleavable design suitable for stable conjugation.
  • Provides a hydrophilic spacer to improve solubility and reduce steric hindrance.
  • Commonly used in ADC and PROTAC linker synthesis.
  • Molecular weight approximately 544.63 g/mol.
  • High purity, specified at 98.0%.
  • Available in small-scale packaging suitable for research (100 MG).

ENCOMPASS_PREFERRED
1,175

Medchemexpress LLC Acetic acid, 2-(2-cyclooctyn-1-yloxy)-, 2,5-dioxo-1-pyrrolidinyl ester | 1425803-45-7 | MFCD28898688 | 95.0% | 279.29 g/mol | C14H17NO5 | 50 MG
SDP

Cyclooctyne-O-NHS ester is a cyclooctyne-containing N-hydroxysuccinimide (NHS) ester used as a cleavable ADC linker and click-chemistry reagent for bioconjugation. It undergoes azide-alkyne cycloaddition to enable antibody-drug conjugate construction, labeling, and related conjugation workflows.

  • Cleavable ADC linker for antibody-drug conjugate synthesis.
  • Reacts with azide groups via strain-promoted and copper-catalyzed azide-alkyne cycloaddition.
  • NHS ester chemistry enables efficient conjugation to primary amines.
  • Supplied as a solid in multiple pack sizes suitable for small-scale synthesis.
  • Datasheet and safety data sheet available for handling and storage guidance.

ENCOMPASS_PREFERRED
1,176

Medchemexpress LLC M-PEG11-acid | 2280998-74-3 | 98.0% | 544.63 g·mol⁻¹ | C24H48O13 | 50 MG
SDP

m-PEG11-acid is a monomethyl polyethylene glycol (11 ethylene glycol units) acid linker used as a reagent for antibody-drug conjugate and PROTAC linker synthesis, and for general bioconjugation.

  • Monomethyl PEG with 11 ethylene glycol units.
  • Molecular weight 544.63 g·mol⁻¹.
  • Purity 98.0%.
  • Cas number 2280998-74-3.
  • Available in small pack sizes, including 50 mg and 100 mg.

ENCOMPASS_PREFERRED
1,177

Medchemexpress LLC Azido-PEG3-SS-NHS | 436.50 | C15H24N4O7S2 | 10 MG
SDP

Azido-PEG3-SS-NHS is an azide-functionalized, cleavable PEG3 linker used for bioconjugation and antibody-drug conjugate (ADC) synthesis. It contains an NHS ester for amine coupling, a disulfide (SS) cleavage site, and an azide group for click chemistry reactions (CuAAC and SPAAC).

  • Cleavable disulfide linker enabling reductive release
  • Contains NHS ester for efficient amine conjugation
  • Azide group supports CuAAC and strain-promoted click chemistries
  • Liquid form; molecular weight 436.50 and formula C15H24N4O7S2
  • Available in small milligram quantities (e.g., 5 mg, 10 mg)

ENCOMPASS_PREFERRED
1,178

eMolecules​ 58-85-5 | D-Biotin | Oakwood Chemicals | MFCD00005541 | 244.310 | C10H16N2O3S | 99.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 250mg | 486568227

D-Biotin | Oakwood Chemicals | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 99.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 250mg | 486568227

ENCOMPASS_PREFERRED
1,179

eMolecules​ 1800414-71-4 | Azido-PEG11-amine | Broadpharm | MFCD08274605 | 570.681 | C24H50N4O11 | 98.000 | NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 1g | 296213760

Azido-PEG11-amine | Broadpharm | 1800414-71-4 | MFCD08274605 | 570.681 | C24H50N4O11 | 98.000 | NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 1g | 296213760

ENCOMPASS_PREFERRED
1,180

eMolecules​ 58-85-5 | D-Biotin | Ochem Incorporation | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 5g | 773150949

D-Biotin | Ochem Incorporation | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 5g | 773150949

ENCOMPASS_PREFERRED
1,181

Medchemexpress LLC Mal-PEG3-NHS ester | 1537892-36-6 | 99.5% | 398.36 g/mol | C17H22N2O9 | 250 MG
SDP

Mal-PEG3-NHS ester is a heterobifunctional PEG3 linker containing a maleimide group and an N-hydroxysuccinimide (NHS) ester. It is used as a noncleavable linker for antibody-drug conjugate synthesis and for coupling thiol-bearing ligands to amine-functionalized targets.

  • Heterobifunctional maleimide-NHS PEG3 linker
  • Suitable for thiol-to-amine bioconjugation
  • Noncleavable linker for antibody-drug conjugate synthesis
  • High purity (99.5%)
  • Soluble in DMSO; for research use only

ENCOMPASS_PREFERRED
1,182

eMolecules​ 2428400-08-0 | Amino-PEG11-t-butyl ester | Broadpharm629.785 | C29H59NO13 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN | 1g | 603111796

Amino-PEG11-t-butyl ester | Broadpharm | 2428400-08-0629.785 | C29H59NO13 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN | 1g | 603111796

ENCOMPASS_PREFERRED
1,183

eMolecules​ 58-85-5 | D-Biotin | Oakwood Chemicals | MFCD00005541 | 244.310 | C10H16N2O3S | 99.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 1g | 480169793

D-Biotin | Oakwood Chemicals | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 99.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 1g | 480169793

ENCOMPASS_PREFERRED
1,184

eMolecules​ 58-85-5 | D-Biotin | Chemodex Ltd. | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 1g | 482921469

D-Biotin | Chemodex Ltd. | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 1g | 482921469

ENCOMPASS_PREFERRED
1,185

eMolecules​ 58-85-5 | Biotin | Accela ChemBio (ASD) | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 25g | 444759670

Biotin | Accela ChemBio (ASD) | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 25g | 444759670

ENCOMPASS_PREFERRED