Biotin and derivatives
Medchemexpress LLC Biotin-peg-biotin | 194920-55-3 | 99.3% | C26H44N6O6S2 | 100 MG
Biotin-PEG-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC M-PEG-NHS ester (MW 10000) | 92451-01-9 | 98.0% | Poly(oxy-1,2-ethanediyl), α-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-ω-methoxy- | 25 MG
m-PEG-NHS ester (MW 10000) is a PEG-based PROTAC linker. It is for research use only and not sold to patients. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. These compounds contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Composed of PEG, alkyl, and ether groups
eMolecules 174569-25-6 | m-PEG12-NHS ester | Broadpharm | MFCD13184970 | 685.761 | C30H55NO16 | 95.000 | COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O | 100mg | 200622526
m-PEG12-NHS ester | Broadpharm | 174569-25-6 | MFCD13184970 | 685.761 | C30H55NO16 | 95.000 | COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O | 100mg | 200622526
Medchemexpress LLC Biotin-C10-NHS ester | 887628-40-2 | MFCD05865045 | 99.5% | 524.67 | C25H40N4O6S | 5 MG
Biotin-C10-NHS ester is an alkyl/ether-based PROTAC linker bearing an N-hydroxysuccinimide (NHS) ester and a ten-carbon biotin spacer. It reacts with primary amines to install a biotin handle for affinity capture, target identification, and PROTAC probe construction. The compound is supplied as a solid with reported high purity and recommended low-temperature storage to maintain stability.
- Alkyl/ether-based PROTAC linker suited for probe design.
- NHS ester for efficient coupling to primary amines.
- Ten-carbon biotin spacer for robust affinity capture.
- Supplied as a solid with reported high purity.
- Storage conditions preserve stability (powder -20°C).
Medchemexpress LLC IL-13 Human Biotin 20ug
IL-13 protein is a cytokine involved in allergic inflammation immune response to parasites and B cell proliferation IL-13 Protein Human (Biotinylated HEK293 Avi-His) is the recombinant human-derived IL-13 protein expressed by HEK293 with C-Avi C-6 His labeled tag
eMolecules 1807518-72-4 | Mal-PEG1-NHS ester | Medchem Express | MFCD26127783 | 310.262 | C13H14N2O7 | 98.000 | O=C(CCOCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O | 250mg | 527575115
Mal-PEG1-NHS ester | Medchem Express | 1807518-72-4 | MFCD26127783 | 310.262 | C13H14N2O7 | 98.000 | O=C(CCOCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O | 250mg | 527575115
Medchemexpress LLC Bis-SS-C3-NHS ester | 98604-88-7 | 98.0% | 432.47 | C16H20N2O8S2 | 1 G
Bis-SS-C3-NHS ester is a disulfide-cleavable N-hydroxysuccinimide (NHS) ester linker used for bioconjugation and antibody-drug conjugate (ADC) synthesis. It couples to primary amines via NHS-ester chemistry and releases payloads under reducing intracellular conditions.
- Molecular weight: 432.47
- Chemical formula: C16H20N2O8S2
- Cas number: 98604-88-7
- Purity: 98.0%
- Appearance: white to off-white solid
- Reactive group: NHS ester for coupling to primary amines
- Application: cleavable disulfide linker for ADC synthesis and bioconjugation
- Available pack size: 1 g
Medchemexpress LLC Biotin-Oxytocin | 99.9% | 1233.48 | 1 MG
Biotin-Oxytocin is a biologically active peptide. It is Oxytocin that has been N-terminally labeled with Biotin.
- Biological active peptide.
- N-terminally labeled.
![Medchemexpress LLC 2,5-dioxopyrrolidin-1-yl 3-((2-(((((1R,8S,9S)-bicyclo[6.1.0]non-4-yn-9-yl)methoxy)carbonyl)amino)... | 95.0% | 454.56 g/mol | C20H26N2O6S2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000203370.png-250.jpg)
Medchemexpress LLC 2,5-dioxopyrrolidin-1-yl 3-((2-(((((1R,8S,9S)-bicyclo[6.1.0]non-4-yn-9-yl)methoxy)carbonyl)amino)... | 95.0% | 454.56 g/mol | C20H26N2O6S2 | 10 MG
BCN-SS-NHS is a cleavable linker reagent containing an NHS ester and a strained bicyclo[6.1.0]nonyne (BCN) moiety. It is used for strain-promoted alkyne-azide cycloaddition (SPAAC) click chemistry and to introduce a cleavable disulfide-containing linker arm in bioconjugation and antibody-drug conjugate synthesis.
- Used for SPAAC click chemistry
- Contains an NHS ester for efficient amine coupling
- Includes a disulfide-cleavable linker for intracellular release
- Suitable for antibody-drug conjugate and bioconjugation workflows
- Available in small-scale research quantities
Medchemexpress LLC GFRAL Human Biotin 50ug | 50ug
The GFRAL protein is a brainstem-restricted receptor for GDF15 that regulates food intake energy expenditure and body weight in response to metabolic and toxin-induced stress GFRAL binds to its ligand GDF15 interacts with RET and activates the MAPK and AKT signaling pathways GFRAL Protein Human (Biotinylated HEK293 His-Avi) is the recombinant human-derived GFRAL protein expressed by HEK293 with C-Avi C-His labeled tag
Medchemexpress LLC 5,8,11,14,17-Pentaoxa-2-azaeicosanedioic acid, 1-(1,1-dimethylethyl) 20-(2,5-dioxo-1-pyrrolidinyl) ester | 2055040-78-1 | 96.9% | 506.54 | 250 MG
Boc-N-PEG5-C2-NHS ester is a PEG-based PROTAC linker. It can be used in the synthesis of PROTACs, which exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
eMolecules 2280998-74-3 | Medchem Express | m-PEG11-acid | 50mg | 721309591 | HY-140501 | MFCD27977512 | 544.635 | C24H48O13
Ambeed | 2-(4-Carbamimidoylphenyl)acetic acid hydrochloride | 100mg | 490510431 | A142490 | 52798-09-1 | MFCD11505975 | 214.650 | C9H11ClN2O2
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Medchemexpress LLC Sulfo-Cy3-NHS disodium | 865.90 g/mol | C36H41N3Na2O13S3 | 10 MG
Sulfo-Cy3-NHS disodium is a water-soluble Cyanine3 (Cy3) derivative bearing an NHS ester for amine-reactive conjugation. The sulfonate groups increase aqueous solubility, making this reagent suitable for labeling proteins, peptides, and antibodies for fluorescence detection and imaging.
- Water-soluble NHS ester for efficient labeling of primary amines.
- Improved aqueous solubility due to sulfonate groups.
- Suitable for conjugation to proteins, antibodies, and peptides.
- Enables fluorescence detection and imaging applications.
- Stable solid form for routine laboratory handling and storage per manufacturer instructions.
Medchemexpress LLC GGGYK-Biotin | 99.8% | 706.81 | 10 MG
GGGYK-Biotin is a substrate peptide designed to study the substrate specificity of Sortase A. It can be used to develop Sortase A variants with different substrate specificities.
- Purity of 99.75%
- Molecular weight of 706.81
- Appears as a white to off-white solid
- Sequence: Gly-Gly-Gly-Tyr-Lys-Biotin
- Formula: C31H46N8O9S
Medchemexpress LLC Sulfo-NHS-Acetate | 152305-87-8 | 98.0% | C6H7NO7S | 100 MG
Sulfo-NHS-Acetate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. It is intended for research use only.
- Alkyl chain-based PROTAC linker
- Used in the synthesis of PROTACs
- For research use only