Cycloheptathiophenes
Apexbio Technology LLC Clemastine Fumarate 14976-57-9 200mg
Clemastine Fumarate (CAS 14976-57-9) is a small molecule that functions as a selective antagonist of the histamine H1 receptor It demonstrates high affinity for the receptor with an inhibitory concentration (IC50) of 3 nM By blocking histamine H1 receptor-mediated signaling clemastine fumarate is utilized in research to study histaminergic pathways and allergic responses It is also employed to investigate the pharmacological modulation of H1 receptor activity in various cellular and in vivo models
Apexbio Technology LLC Rupatadine Fumarate 182349-12-8 10mM (in 1mL Ethanol)
Rupatadine Fumarate (CAS 182349-12-8) is a small molecule antagonist targeting platelet-activating factor receptor (PAFR) and histamine H1 receptor It exhibits binding affinities (K i) of 550 nM at PAFR and 102 nM at the histamine H1 receptor effectively inhibiting signaling mediated by these pathways Through dual antagonism rupatadine fumarate disrupts inflammatory and allergic responses regulated by platelet-activating factor and histamine signaling Currently in Phase 2 clinical development it serves as a valuable pharmacological tool for studying inflammation and allergic conditions
Selleck Chemical LLC Ferrous fumarate
Ferrous fumarate (Iron(II)) is the fumarate salt form of the mineral iron and is used in treatment of iron deficiency anemia
Apexbio Technology LLC Fesoterodine Fumarate 286930-03-8 5mg
Fesoterodine Fumarate (CAS 286930-03-8) is a synthetic antimuscarinic agent that acts as a competitive antagonist at muscarinic acetylcholine receptors particularly the M3 subtype in the bladder detrusor muscle By inhibiting these receptors the compound modulates involuntary bladder contractions reducing symptoms associated with overactive bladder syndrome such as urgency and frequency Fesoterodine Fumarate is utilized in biomedical research to study cholinergic signaling mechanisms involved in urinary function and to explore pharmacological interventions targeting muscarinic pathways in urological disorders
Medchemexpress LLC 2-butenedioic acid (2E)-, 1-ethyl ester | 2459-05-4 | MFCD00002699 | 99.6% | 144.13 g/mol | C6H8O4 | 50 G
Monoethyl fumarate is the monoethyl ester of fumaric acid supplied as a research reagent and reported Nrf2 activator. It is used in biochemical research and as a preservative and polymerization agent for macromolecular materials. The compound is available as a solid and as a 10 mM solution in DMSO for experimental convenience.
- Activates Nrf2 signaling in research assays.
- High reported purity (99.62%).
- Molecular weight 144.13 g/mol and chemical formula C6H8O4.
- Available in multiple pack sizes and solution form.
- Useful as a preservative and polymerization agent for macromolecular materials.
- For research use only; not for clinical use.
Apexbio Technology LLC Ibutilide Fumarate 122647-32-9 10mM (in 1mL DMSO)
Ibutilide Fumarate (CAS 122647-32-9) is a small molecule classified as a Class III antiarrhythmic agent It acts primarily by enhancing slow inward sodium currents and delaying repolarization through inhibition of the rapid component of the cardiac delayed rectifier potassium current (IKr) resulting in prolongation of the cardiac action potential Ibutilide is utilized in research to investigate pharmacological cardioversion of atrial arrhythmias specifically studying the acute conversion of atrial fibrillation and atrial flutter to normal sinus rhythm Its properties make it valuable for exploring the mechanisms of antiarrhythmic therapy and cardiac electrophysiology
Medchemexpress LLC Fumarate hydratase-IN-2 (sodium salt) | 2070009-45-7 | 98.7% | 440.47 | C25H25N2NaO4 | 100 MG
Fumarate hydratase-IN-2 (sodium salt) is a cell-permeable, competitive inhibitor of fumarate hydratase with a reported Ki of 4.5 μM and nutrient-dependent cytotoxicity. Supplied as a sodium salt, it is intended for biochemical and cell-based studies probing fumarate hydratase activity and related metabolic pathways.
- Cell-permeable, competitive inhibitor of fumarate hydratase (Ki = 4.5 μM).
- Reported nutrient-dependent cytotoxicity in cell assays.
- High purity suitable for research use (LCMS 98.7%).
- Molecular weight 440.47; formula C25H25N2NaO4.
- Available in small-scale solid quantities for assay preparation (for example, 100 mg).
American Radiolabeled Chemicals Inc KF COLD 10ME
Ketotifen fumarate 10mg as solid, M.W. 425.5, Solvent: Solid, CAS# 34580-14-8
Medchemexpress LLC Ocifisertib fumarate | 1616420-30-4 | >98.0% | 650.7 g/mol | C37H38N4O7 | 50MG
Ocifisertib fumarate is the fumarate salt of CFI-400945, a potent, selective, and orally bioavailable inhibitor of polo-like kinase 4 (PLK4) supplied for research use in biochemical and cellular studies of PLK4-related pathways and antineoplastic activity.
- Fumarate salt form of the PLK4 inhibitor.
- Potent biochemical activity: PLK4 Ki = 0.26 nM; PLK4 IC50 = 2.8 nM.
- Molecular formula C37H38N4O7 and molecular weight 650.7 g/mol.
- High purity (>98.0% by HPLC) suitable for research applications.
- Supplied in small research pack sizes, including 50 mg.
Apexbio Technology LLC Ibutilide Fumarate 122647-32-9 100mg
Ibutilide Fumarate (CAS 122647-32-9) is a small molecule classified as a Class III antiarrhythmic agent It acts primarily by enhancing slow inward sodium currents and delaying repolarization through inhibition of the rapid component of the cardiac delayed rectifier potassium current (IKr) resulting in prolongation of the cardiac action potential Ibutilide is utilized in research to investigate pharmacological cardioversion of atrial arrhythmias specifically studying the acute conversion of atrial fibrillation and atrial flutter to normal sinus rhythm Its properties make it valuable for exploring the mechanisms of antiarrhythmic therapy and cardiac electrophysiology