Cycloheptathiophenes
![Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate, 96%](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-40106-13-6.jpg-250.jpg)
Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate, 96%
CAS: 40106-13-6 Molecular Formula: C12H17NO2S Molecular Weight (g/mol): 239.333 MDL Number: MFCD00216932 InChI Key: XTUHIGALMIGZST-UHFFFAOYSA-N Synonym: ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-4h,5h,6h,7h,8h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta-b thiophene-3-carboxylate,ethyl 2-amino-4,5,6,7,8-pentahydrocyclohepta 1,2-b thiophene-3-carboxylate,2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylic acid ethyl ester,ethyl 2-aminocyclohepta b thiophene-3-carboxylate,aronis24232,ethyl 2-aminocycloheptathiophene-3-carboxylate,2-amino-3-ethoxy-carbonyl-4,5-pentamethylenethiophene PubChem CID: 292644 IUPAC Name: ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate SMILES: CCOC(=O)C1=C(SC2=C1CCCCC2)N
Ketotifen fumarate, 99%
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.499 MDL Number: MFCD00079394 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N Synonym: ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro PubChem CID: 5282408 IUPAC Name: (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
Ketotifen Hydrogen Fumarate, EP, 98.5-101%, Spectrum™ Chemical
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.50 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N IUPAC Name: (2E)-but-2-enedioic acid; 2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.0³,⁷]tetradeca-1(14),3(7),4,10,12-pentaen-8-one SMILES: OC(=O)\C=C\C(O)=O.CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12
Ketotifen Fumarate 98.0+%, TCI America™
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.499 MDL Number: MFCD00079394 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N Synonym: ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro PubChem CID: 5282408 IUPAC Name: (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
Pizotifen 98.0+%, TCI America™
CAS: 15574-96-6 Molecular Formula: C19H21NS Molecular Weight (g/mol): 295.444 MDL Number: MFCD00864192 InChI Key: FIADGNVRKBPQEU-UHFFFAOYSA-N Synonym: 4-[9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene]-1-methylpiperidine, Sandomigran PubChem CID: 27400 ChEBI: CHEBI:50212 IUPAC Name: 4-(4,5-dihydrobenzo[1,2]cyclohepta[3,4-b]thiophen-10-ylidene)-1-methylpiperidine SMILES: CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1
Medchemexpress LLC Formoterol fumarate | 43229-80-7 | >99.9% | C19H24N2O4 . 1/2C4H4O4 | 1 ML
Formoterol fumarate is a selective β2-adrenoceptor agonist, demonstrating similar β2-adrenoceptor selectivity to Salbutamol and Terbutaline. This compound is known for its ability to abolish the contraction induced by Acetylcholine in bronchioles. It is commonly utilized in research applications for conditions such as chronic obstructive pulmonary disease and bronchial asthma.
- Selective β2-adrenoceptor agonist
- Abolishes acetylcholine-induced contraction in bronchioles
- Used in research for chronic obstructive pulmonary disease
- Utilized in research for bronchial asthma
Medchemexpress LLC Bedaquiline (fumarate) | 845533-86-0 | 99.99% | 671.58 | 25 MG
Bedaquiline (fumarate) is a diarylquinoline antibiotic that targets ATP synthase and is effective for the treatment of Mycobacterium tuberculosis infections. It inhibits the growth of TDR M. tuberculosis strains and shows high activity against Mycobacterium avium and moderate activity against NTM species. This product is for research use only.
- Targets ATP synthase
- Effective for treating Mycobacterium tuberculosis infections
- Inhibits growth of TDR M. tuberculosis strains
- High activity against Mycobacterium avium
- Moderate activity against NTM species
- For research use only
TARGETMOL CHEMICALS INC RUPATADINE FUMARATE 500MG
Also available in 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Rupatadine Fumarate (Rinialer) (UR-12592 Fumarate) is a potent dual PAF/H1 antagonist with Ki of 0.55/0.1 uM. purity: 99%
Apexbio Technology LLC Rupatadine Fumarate 182349-12-8 10mM (in 1mL Ethanol)
Rupatadine Fumarate (CAS 182349-12-8) is a small molecule antagonist targeting platelet-activating factor receptor (PAFR) and histamine H1 receptor It exhibits binding affinities (K i) of 550 nM at PAFR and 102 nM at the histamine H1 receptor effectively inhibiting signaling mediated by these pathways Through dual antagonism rupatadine fumarate disrupts inflammatory and allergic responses regulated by platelet-activating factor and histamine signaling Currently in Phase 2 clinical development it serves as a valuable pharmacological tool for studying inflammation and allergic conditions
Medchemexpress LLC Tepilamide fumarate | 1208229-58-6 | 99.8% | 243.26 | 100 MG
Tepilamide fumarate is an oral fumaric acid ester that acts as a proagent of Monomethyl fumarate. It is used in the research of moderate to severe chronic plaque psoriasis and can enhance the effectiveness of oncolytic viruses.
- Oral fumaric acid ester
- Proagent of Monomethyl fumarate
- Enhances effectiveness of oncolytic viruses
- Selectively promotes oncolytic virus infection in cancer cells without affecting healthy tissues
- Used in research for moderate to severe chronic plaque psoriasis
- Potential to enhance virus-based therapy
- Solid, white to off-white appearance
Medchemexpress LLC Bedaquiline fumarate | 845533-86-0 | 99.99% | 671.58 | 1 ML
Bedaquiline fumarate, also known as R403323 or TMC207 fumarate, is a potent diarylquinoline antibiotic that primarily targets ATP synthase. This mechanism of action makes it highly effective for treating Mycobacterium tuberculosis infections, including difficult-to-treat multidrug-resistant (MDR) strains. It is intended for research use only.
- Antibiotic mechanism: Functions as a bacterial inhibitor by targeting ATP synthase
- Antituberculosis activity: Effective against Mycobacterium tuberculosis infections, including multidrug-resistant strains
- In vitro efficacy: Inhibits growth of TDR M. tuberculosis strains and shows high activity against Mycobacterium avium
- Research use: Intended for laboratory research and development
Medchemexpress LLC Ocifisertib fumarate | 1616420-30-4 | >98.0% | 650.7 g/mol | C37H38N4O7 | 50MG
Ocifisertib fumarate is the fumarate salt of CFI-400945, a potent, selective, and orally bioavailable inhibitor of polo-like kinase 4 (PLK4) supplied for research use in biochemical and cellular studies of PLK4-related pathways and antineoplastic activity.
- Fumarate salt form of the PLK4 inhibitor.
- Potent biochemical activity: PLK4 Ki = 0.26 nM; PLK4 IC50 = 2.8 nM.
- Molecular formula C37H38N4O7 and molecular weight 650.7 g/mol.
- High purity (>98.0% by HPLC) suitable for research applications.
- Supplied in small research pack sizes, including 50 mg.
Medchemexpress LLC Diethyl fumarate | 623-91-6 | 99.0% | 172.18 | 10 G
Diethyl fumarate is a decomposition product of Malathion 9 and a reactant in the Diels-Alder reaction. It is a reputed skin irritant and can cause non-immunologic contact urticaria on the skin. Diethyl fumarate and Curcumin hybridize to exert neuroprotective effects.
- Decomposition product of Malathion 9.
- Reactant in Diels-Alder reaction.
- Causes dose-dependent swelling of ears in guinea pigs.
- Curcumin hybrids show neuroprotective effects in C. elegans model of PD.
- For research use only.
Medchemexpress LLC Cevipabulin fumarate | 849550-67-0 | 99.9% | 580.89 | 50 MG
Cevipabulin fumarate (TTI-237 fumarate) is an oral, microtubule-active, antitumor compound. It inhibits the binding of [3H]NSC 49842 to tubulin, with an IC50 of 18-40 nM for cytotoxicity in human tumor cell lines.
- Microtubule-active, antitumor compound
- Shows good activity (18-40 nM IC50 values) on ovarian, breast, prostate, and cervical tumor cell lines
- Produces sub-G1 nuclei at low concentrations (20-40 nM)
- Causes a strong G2-M block at concentrations above 50 nM
- Active via intravenous (i.v.) and oral (p.o.) administration against human tumor xenografts in mice, with good antitumor activity at 20 and 15 mg/kg