Cycloheptathiophenes
Ketotifen fumarate, 99%
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.499 MDL Number: MFCD00079394 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N Synonym: ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro PubChem CID: 5282408 IUPAC Name: (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
![Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate, 96%](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-40106-13-6.jpg-250.jpg)
Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate, 96%
CAS: 40106-13-6 Molecular Formula: C12H17NO2S Molecular Weight (g/mol): 239.333 MDL Number: MFCD00216932 InChI Key: XTUHIGALMIGZST-UHFFFAOYSA-N Synonym: ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-4h,5h,6h,7h,8h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta-b thiophene-3-carboxylate,ethyl 2-amino-4,5,6,7,8-pentahydrocyclohepta 1,2-b thiophene-3-carboxylate,2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylic acid ethyl ester,ethyl 2-aminocyclohepta b thiophene-3-carboxylate,aronis24232,ethyl 2-aminocycloheptathiophene-3-carboxylate,2-amino-3-ethoxy-carbonyl-4,5-pentamethylenethiophene PubChem CID: 292644 IUPAC Name: ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate SMILES: CCOC(=O)C1=C(SC2=C1CCCCC2)N
Ketotifen Hydrogen Fumarate, EP, 98.5-101%, Spectrum™ Chemical
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.50 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N IUPAC Name: (2E)-but-2-enedioic acid; 2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-8-one SMILES: OC(=O)\C=C\C(O)=O.CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12
Ketotifen Fumarate 98.0+%, TCI America™
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.499 MDL Number: MFCD00079394 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N Synonym: ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro PubChem CID: 5282408 IUPAC Name: (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
Pizotifen 98.0+%, TCI America™
CAS: 15574-96-6 Molecular Formula: C19H21NS Molecular Weight (g/mol): 295.444 MDL Number: MFCD00864192 InChI Key: FIADGNVRKBPQEU-UHFFFAOYSA-N Synonym: 4-[9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene]-1-methylpiperidine, Sandomigran PubChem CID: 27400 ChEBI: CHEBI:50212 IUPAC Name: 4-(4,5-dihydrobenzo[1,2]cyclohepta[3,4-b]thiophen-10-ylidene)-1-methylpiperidine SMILES: CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1
Selleck Chemical LLC Ferrous fumarate
Ferrous fumarate (Iron(II)) is the fumarate salt form of the mineral iron and is used in treatment of iron deficiency anemia
Apexbio Technology LLC GR 89696 fumarate 126766-32-3 10mg
GR 89696 fumarate (CAS 126766-32-3) is a selective agonist of the 2-opioid receptor By specifically activating 2 subtypes this small molecule modulates neural signaling pathways implicated in sensory processing particularly pain and pruritus Experimental studies have demonstrated that GR 89696 fumarate induces physiological effects in the nervous system through 2-opioid receptor activation This compound has been widely utilized as a pharmacological tool in the investigation of neurocutaneous disorders and the underlying mechanisms of opioid receptor-mediated modulation of somatosensory functions
Apexbio Technology LLC Bedaquiline fumarate 845533-86-0 50mg
Bedaquiline fumarate (CAS 845533-86-0) is a small-molecule inhibitor targeting ATP synthase of Mycobacterium tuberculosis It is designed to inhibit mycobacterial ATP synthase thereby disrupting ATP biosynthesis and bacterial energy metabolism Bedaquiline fumarate exerts its biological activity primarily through selective inhibition of ATP synthase In biochemical assays bedaquiline fumarate demonstrates potent inhibitory activity with an IC50 value of approximately 30 nM against M tuberculosis ATP synthase Based on these pharmacological properties bedaquiline fumarate holds research potential in studying tuberculosis pathogenesis mechanisms of antibiotic resistance and evaluating therapeutic strategies for mycobacterial infections
Medchemexpress LLC Fumarate hydratase-IN-2 (sodium salt) | 2070009-45-7 | 98.7% | 440.47 | C25H25N2NaO4 | 100 MG
Fumarate hydratase-IN-2 (sodium salt) is a cell-permeable, competitive inhibitor of fumarate hydratase with a reported Ki of 4.5 μM and nutrient-dependent cytotoxicity. Supplied as a sodium salt, it is intended for biochemical and cell-based studies probing fumarate hydratase activity and related metabolic pathways.
- Cell-permeable, competitive inhibitor of fumarate hydratase (Ki = 4.5 μM).
- Reported nutrient-dependent cytotoxicity in cell assays.
- High purity suitable for research use (LCMS 98.7%).
- Molecular weight 440.47; formula C25H25N2NaO4.
- Available in small-scale solid quantities for assay preparation (for example, 100 mg).
Medchemexpress LLC Diroximel fumarate | 1577222-14-0 | ≥98.0% | 255.23 g/mol | C11H13NO6 | 50 MG
Diroximel fumarate is supplied as a research-grade small-molecule reagent intended for laboratory studies. This listing represents a 50 MG pack of the prodrug of monomethyl fumarate and is provided for experimental and analytical use in research settings; it is not for clinical or human use.
- For research use only, not for human or clinical use.
- Supplied as a small 50 MG pack suitable for laboratory testing.
- High purity, typically ≥98.0%.
- Molecular weight 255.23 g/mol and formula C11H13NO6.
- Useful for studies of fumarate metabolism and related biochemical pathways.
Apexbio Technology LLC Fesoterodine Fumarate 286930-03-8 5mg
Fesoterodine Fumarate (CAS 286930-03-8) is a synthetic antimuscarinic agent that acts as a competitive antagonist at muscarinic acetylcholine receptors particularly the M3 subtype in the bladder detrusor muscle By inhibiting these receptors the compound modulates involuntary bladder contractions reducing symptoms associated with overactive bladder syndrome such as urgency and frequency Fesoterodine Fumarate is utilized in biomedical research to study cholinergic signaling mechanisms involved in urinary function and to explore pharmacological interventions targeting muscarinic pathways in urological disorders
Medchemexpress LLC Bedaquiline (fumarate) | 845533-86-0 | 99.99% | 671.58 | 25 MG
Bedaquiline (fumarate) is a diarylquinoline antibiotic that targets ATP synthase and is effective for the treatment of Mycobacterium tuberculosis infections. It inhibits the growth of TDR M. tuberculosis strains and shows high activity against Mycobacterium avium and moderate activity against NTM species. This product is for research use only.
- Targets ATP synthase
- Effective for treating Mycobacterium tuberculosis infections
- Inhibits growth of TDR M. tuberculosis strains
- High activity against Mycobacterium avium
- Moderate activity against NTM species
- For research use only
Medchemexpress LLC Cevipabulin fumarate | 849550-67-0 | 99.9% | 580.89 | 25 MG
Cevipabulin fumarate is an oral, microtubule-active, antitumor compound that inhibits the binding of [3H]NSC 49842 to tubulin. It exhibits an IC50 of 18-40 nM for cytotoxicity in human tumor cell lines, demonstrating good activity on various cancer cell lines.
- Oral, microtubule-active, antitumor compound
- Inhibits binding of [3H]NSC 49842 to tubulin
- Shows cytotoxicity in human tumor cell lines (IC50 of 18-40 nM)
- Active against ovarian, breast, prostate, and cervical tumors
- Produces sub-G1 nuclei at low concentrations (20-40 nM)
- Causes strong G2-M block at concentrations above 50 nM
- Active in vivo against human tumor xenografts
- Exhibits dose-dependent antitumor activity
- Targets microtubule/tubulin and cell cycle/DNA damage pathways
Medchemexpress LLC Bedaquiline fumarate | 845533-86-0 | 99.98% | 671.58 | 50 MG
Bedaquiline fumarate is an analytical standard and a diarylquinoline antibiotic that targets ATP synthase. It is effective for the treatment of Mycobacterium tuberculosis infections and is intended for research and analytical applications.
- Analytical standard grade
- Reference standard supplied assay
- Effective against Mycobacterium tuberculosis infections
- Commonly used in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS applications
Medchemexpress LLC Crozbaciclib fumarate | 2567494-39-5 | 99.4% | 604.65 | 10 MG
Crozbaciclib fumarate is a potent CDK4/6 inhibitor, demonstrating significant anti-proliferative effects by arresting the U87MG cell line exclusively in G1. It has shown promising results in vivo, including substantial tumor growth inhibition in orthotopic xenograft mouse models of glioblastoma multiforme.
- Potent CDK4/6 inhibitor with IC50s of 3 nM (CDK4) and 1 nM (CDK6).
- Acts as an anti-proliferative agent, arresting U87MG cells in G1.
- Exhibits tumor growth inhibition from 62% to 99% in glioblastoma multiforme xenograft models.
- Increases lifespan by 162% in mice at a dose of 50 mg/kg.