Cycloheptathiophenes
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Ketotifen Hydrogen Fumarate, EP, 98.5-101%, Spectrum™ Chemical
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CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.50 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N IUPAC Name: (2E)-but-2-enedioic acid; 2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.0³,⁷]tetradeca-1(14),3(7),4,10,12-pentaen-8-one SMILES: OC(=O)\C=C\C(O)=O.CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12
| CAS | 34580-14-8 |
|---|---|
| Molecular Weight (g/mol) | 425.50 |
| SMILES | OC(=O)\C=C\C(O)=O.CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12 |
| IUPAC Name | (2E)-but-2-enedioic acid; 2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.0³,⁷]tetradeca-1(14),3(7),4,10,12-pentaen-8-one |
| InChI Key | YNQQEYBLVYAWNX-WLHGVMLRSA-N |
| Molecular Formula | C23H23NO5S |
Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate, 96%
CAS: 40106-13-6 Molecular Formula: C12H17NO2S Molecular Weight (g/mol): 239.333 MDL Number: MFCD00216932 InChI Key: XTUHIGALMIGZST-UHFFFAOYSA-N Synonym: ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-4h,5h,6h,7h,8h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta-b thiophene-3-carboxylate,ethyl 2-amino-4,5,6,7,8-pentahydrocyclohepta 1,2-b thiophene-3-carboxylate,2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylic acid ethyl ester,ethyl 2-aminocyclohepta b thiophene-3-carboxylate,aronis24232,ethyl 2-aminocycloheptathiophene-3-carboxylate,2-amino-3-ethoxy-carbonyl-4,5-pentamethylenethiophene PubChem CID: 292644 IUPAC Name: ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate SMILES: CCOC(=O)C1=C(SC2=C1CCCCC2)N
| PubChem CID | 292644 |
|---|---|
| CAS | 40106-13-6 |
| Molecular Weight (g/mol) | 239.333 |
| MDL Number | MFCD00216932 |
| SMILES | CCOC(=O)C1=C(SC2=C1CCCCC2)N |
| Synonym | ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-4h,5h,6h,7h,8h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta-b thiophene-3-carboxylate,ethyl 2-amino-4,5,6,7,8-pentahydrocyclohepta 1,2-b thiophene-3-carboxylate,2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylic acid ethyl ester,ethyl 2-aminocyclohepta b thiophene-3-carboxylate,aronis24232,ethyl 2-aminocycloheptathiophene-3-carboxylate,2-amino-3-ethoxy-carbonyl-4,5-pentamethylenethiophene |
| IUPAC Name | ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate |
| InChI Key | XTUHIGALMIGZST-UHFFFAOYSA-N |
| Molecular Formula | C12H17NO2S |
Ketotifen fumarate, 99%
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.499 MDL Number: MFCD00079394 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N Synonym: ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro PubChem CID: 5282408 IUPAC Name: (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
| PubChem CID | 5282408 |
|---|---|
| CAS | 34580-14-8 |
| Molecular Weight (g/mol) | 425.499 |
| MDL Number | MFCD00079394 |
| SMILES | CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O |
| Synonym | ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro |
| IUPAC Name | (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one |
| InChI Key | YNQQEYBLVYAWNX-WLHGVMLRSA-N |
| Molecular Formula | C23H23NO5S |
Ketotifen Fumarate 98.0+%, TCI America™
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.499 MDL Number: MFCD00079394 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N Synonym: ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro PubChem CID: 5282408 IUPAC Name: (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
| PubChem CID | 5282408 |
|---|---|
| CAS | 34580-14-8 |
| Molecular Weight (g/mol) | 425.499 |
| MDL Number | MFCD00079394 |
| SMILES | CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O |
| Synonym | ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro |
| IUPAC Name | (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one |
| InChI Key | YNQQEYBLVYAWNX-WLHGVMLRSA-N |
| Molecular Formula | C23H23NO5S |
Pizotifen 98.0+%, TCI America™
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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CAS: 15574-96-6 Molecular Formula: C19H21NS Molecular Weight (g/mol): 295.444 MDL Number: MFCD00864192 InChI Key: FIADGNVRKBPQEU-UHFFFAOYSA-N Synonym: 4-[9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene]-1-methylpiperidine, Sandomigran PubChem CID: 27400 ChEBI: CHEBI:50212 IUPAC Name: 4-(4,5-dihydrobenzo[1,2]cyclohepta[3,4-b]thiophen-10-ylidene)-1-methylpiperidine SMILES: CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1
| PubChem CID | 27400 |
|---|---|
| CAS | 15574-96-6 |
| Molecular Weight (g/mol) | 295.444 |
| ChEBI | CHEBI:50212 |
| MDL Number | MFCD00864192 |
| SMILES | CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1 |
| Synonym | 4-[9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene]-1-methylpiperidine, Sandomigran |
| IUPAC Name | 4-(4,5-dihydrobenzo[1,2]cyclohepta[3,4-b]thiophen-10-ylidene)-1-methylpiperidine |
| InChI Key | FIADGNVRKBPQEU-UHFFFAOYSA-N |
| Molecular Formula | C19H21NS |
Sigma Aldrich Diethyl fumarate
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
| Boiling Point | 218°C to 219°C (lit.) |
|---|---|
| Percent Purity | 98% |
| Linear Formula | C2H5OCOCH=CHCOOC2H5 |
| CAS | 623-91-6 |
| Molecular Weight (g/mol) | 172.18 |
| MDL Number | MFCD00064455 |
| Refractive Index | n20/D 1.44 (literature) |
| RTECS Number | EM5950000 |
| Recommended Storage | Room Temperature |
| Molecular Formula | C8H12O4 |
| EINECS Number | 210-819-7 |
| Density | 1.052 g/mL (at 25°C (literature)) |
| Melting Point | 1°C to 2°C (lit.) |
Medchemexpress LLC Monomethyl fumarate-d3 | 1616345-41-5 | MFCD34469902 | 99.0% | 133.117 g/mol | C5H3D3O4 | 1 MG
Monomethyl fumarate-d3 is the deuterium-labeled analogue of monomethyl fumarate, supplied as an isotopically labeled tracer and internal standard for analytical and pharmacokinetic studies. It is intended for research use in quantitative workflows where precise isotope labeling improves detection and quantitation.
- Isotopically labeled internal standard for NMR, GC-MS, and LC-MS.
- Useful as a tracer in pharmacokinetic and metabolic profiling.
- High analytical purity (≈99.0%).
- Provided in small research quantities suitable for analytical assays.
- Molecular formula C5H3D3O4; CAS 1616345-41-5.
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TARGETMOL CHEMICALS INC Fesoterodine fumarate 25MG
Also available in 1 mL, 5 mg, 10 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Fesoterodine fumarate (Toviaz) is the fumarate salt form of fesoterodine, a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties. Fesoterodine is rapidly hydrolyzed in vivo into its active metabolite 5-hydroxymethyl tolterodine, which binds and inhibits muscarinic receptors on the bladder detrusor muscle, thereby preventing bladder contractions or spasms caused by acetylcholine. Purity 98.55%
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Medchemexpress LLC 3aH-indole-3a-carboxylic acid, biphenyl-4-ylmethyl derivative, sodium salt | 2070009-45-7 | 98.7% | 440.47 g/mol | C25H25N2NaO4 | 25 MG
Fumarate hydratase-IN-2 sodium salt is a cell-permeable, competitive fumarate hydratase inhibitor (Ki = 4.5 μM) that exhibits nutrient-dependent cytotoxicity. Supplied as a white to off-white solid intended for research use, it is suitable for cell-based and biochemical studies of fumarate hydratase activity.
- Cell-permeable inhibitor effective in cell-based assays.
- Competitive inhibition with Ki = 4.5 μM for target engagement.
- High purity (98.7%) suitable for research applications.
- Soluble in DMSO and water with warming and sonication.
- Available in small solid quantities and solution formats for flexibility.
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Medchemexpress LLC Bedaquiline fumarate | 845533-86-0 | MFCD28167761 | 100.0% | 671.58 g/mol | C36H35BrN2O6 | 10 MG
Bedaquiline fumarate is an analytical reference standard of the diarylquinoline antibiotic bedaquiline in its fumarate salt form, supplied as a white to off-white solid for research and analytical applications. It is intended for method development, validation, and quantitative or qualitative assays in chromatography and mass spectrometry, and is provided with supporting documentation for safe handling and traceability.
- Analytical standard for HPLC, GC, and MS method development.
- High purity suitable for quantitative and qualitative assays.
- White to off-white solid form for ease of use and handling.
- Available in small reference sizes appropriate for analytical workflows.
- Supplied with SDS and certificate of analysis for traceability.
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Medchemexpress LLC Monomethyl fumarate | 1616345-41-5 | MFCD00063174 | 100.0% | 130.10 g/mol | C5H6O4 | 5 MG
Monomethyl fumarate is the methyl ester metabolite of dimethyl fumarate and is used as a research compound and GPR109A agonist. The material is supplied for laboratory research and analytical reference; available as solid and as DMSO solutions, with analytical documentation available (COA/SDS).
- High purity (≈99.95%).
- Molecular formula C5H6O4 and molecular weight 130.10 g/mol.
- Available as solid, free sample, and 10 mM solutions in DMSO.
- Suitable as a reference standard and for in vitro pharmacology assays.
- Not for human therapeutic or clinical use; research use only.
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TARGETMOL CHEMICALS INC Org-13011 fumarate 1MG
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Org-13011 fumarate1 is an agonist of the 5-HT1A receptor and can be used to study neurological disorders. Purity 98.61%
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TARGETMOL CHEMICALS INC Ro 48-8071 fumarate 25MG
Also available in 1 mL, 5 mg, 10 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Ro 48-8071 fumarate, an inhibitor of OSC (Oxidosqualene cyclase; IC50=6.5 nM), exhibits LDL (low-density lipoprotein) cholesterol-lowering activity. Purity 99.32%
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Medchemexpress LLC VUF11207 fumarate | 1785665-61-3 | 99.9% | 586.65 g/mol | C31H39FN2O8 | 5 MG
VUF11207 fumarate is a research-grade small-molecule agonist of the chemokine receptor CXCR7 (ACKR3). It selectively binds CXCR7 and has been reported to reduce CXCL12-mediated osteoclastogenesis and bone resorption through inhibition of ERK phosphorylation. The compound is supplied for laboratory research use only.
- Selective CXCR7 agonist with reported activity in CXCL12 signaling.
- Reduces CXCL12-mediated osteoclastogenesis and bone resorption by inhibiting ERK phosphorylation.
- High purity suitable for in vitro studies (99.94%).
- Available as solid and as a 10 mM solution in DMSO; multiple solid package sizes available.
- Intended for research use only; not for human or veterinary use.
- Applicable to receptor pharmacology and cell-based signaling assays.
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Cayman Chemical DImethyl fumarate 50g
A lipophilic electrophile that has profound effects on oxidative and immunological pathways; activates the transcription factor Nrf2, resulting in heme oxygenase-1 expression and increased glutathione levels; suppresses the expression of pro-inflammatory cytokines and inhibits angiogenesis
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