Cycloheptathiophenes
Selleck Chemical LLC Zilurgisertib fumarate-5MG
Zilurgisertib fumarate(INCB-000928 fumarate NBU-928 fumarate) is a selective ALK 2 inhibitor It is under development for the treatment of heterotopic ossification and fibrodysplasia ossificans progressiva
Selleck Chemical LLC Zilurgisertib fumarate-25MG
Zilurgisertib fumarate(INCB-000928 fumarate NBU-928 fumarate) is a selective ALK 2 inhibitor It is under development for the treatment of heterotopic ossification and fibrodysplasia ossificans progressiva
Selleck Chemical LLC Fumarate hydratase-IN-1
Fumarate hydratase-IN-1 is a small molecule cell-permeable inhibitor of fumarate hydratase It induce alteration of TCA cycle metabolites modulation of cytosolic processes and substantial redox stress responses
Apexbio Technology LLC Quetiapine Fumarate 111974-72-2 50mg
Quetiapine Fumarate (CAS 111974-72-2) is a small-molecule atypical antipsychotic with antagonistic activity at dopamine (D1 D2) serotonin (5-HT1A 5-HT2) and adrenergic ( 1 2) receptors In vitro it exhibits affinity for multiple neurotransmitter receptors with dopamine-2 binding characteristics similar to clozapine Preclinical in vivo studies demonstrate antipsychotic effects minimal extrapyramidal side effects and a lower propensity for sustained prolactin elevation Quetiapine has been shown to modulate neurotrophin expression and restore hippocampal neurogenesis following chronic stress in animal models supporting its value in neuropsychiatric and neuropharmacological research
Selleck Chemical LLC Vonoprazan Fumarate
Vonoprazan Fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H /K ATPase with IC50 of 19 nM (pH 6 5) controls gastric acid secretion Phase 3
Medchemexpress LLC Rupatadine fumarate | 182349-12-8 | MFCD00926499 | 97.3% | 532.0 g/mol | C30H30ClN3O4 | 5 MG
Rupatadine fumarate is the fumarate salt of the antihistamine rupatadine provided as a laboratory reference standard for analytical testing and method development. The material is supplied in small, quantified packages with supporting documentation for quality control and safe handling.
Medchemexpress LLC Rupatadine fumarate | 182349-12-8 | MFCD00926499 | 97.3% | C30H30ClN3O4 | 10MG
Rupatadine fumarate is an analytical reference standard supplied as a 10 mg pack for research and analytical applications. It corresponds to CAS 182349-12-8, has a molecular formula of C30H30ClN3O4, a molecular weight of 532.03, and is provided with a stated purity of approximately 97.3%. For laboratory research use only.
- Intended for analytical, method development, and validation use.
- Available in a 10 mg pack size.
- Molecular formula C30H30ClN3O4 and molecular weight 532.03.
- Listed purity 97.3%.
- Provided for laboratory research use only.
Apexbio Technology LLC 3-Aminopropionitrile fumarate (2:1) 2079-89-2 500mg
3-Aminopropionitrile fumarate (2 1) (CAS 2079-89-2) is a small molecule derivative originally identified from Apocynaceae species It acts by inhibiting collagen cross-linking through interference with enzymatic pathways responsible for covalent bonding among collagen molecules Modulation of enzyme activity and signaling cascades by this compound leads to altered collagen stability within biological tissues Owing to its capacity to disrupt collagen maturation 3-Aminopropionitrile fumarate (2 1) serves as a valuable tool in studies of fibrotic disorders and related metabolic processes where aberrant extracellular matrix remodeling is implicated
Apexbio Technology LLC Bisoprolol fumarate 104344-23-2 10mM (in 1mL DMSO)
Bisoprolol fumarate (CAS 104344-23-2) is a selective 1-adrenergic receptor antagonist that preferentially inhibits 1-adrenergic signaling with minimal activity at 2 receptors By suppressing 1 receptor-mediated pathways it reduces both heart rate and myocardial contractility following oral administration The compound is utilized in pharmacological and physiological studies to investigate mechanisms underlying hypertension coronary artery disease and stable ventricular dysfunction as well as to evaluate therapeutic interventions that target sympathetic nervous system modulation in cardiovascular research contexts
Apexbio Technology LLC Hoechst 34580 23555-00-2 100mg
Hoechst 34580 is a blue-fluorescent dye routinely employed in biomedical research for labeling cell nuclei and analyzing cell-cycle progression This dye binds selectively to nucleic acids predominantly by interacting with DNA via minor groove binding allowing visualization of nuclear morphology and chromatin structure Upon binding DNA Hoechst 34580 exhibits fluorescence excitation around 392 nm and emission maxima near 440 460 nm suitable for standard fluorescent microscopy Typical working concentrations for cell labeling range between 0 5 and 10 g/mL Due to these characteristics Hoechst 34580 is widely used for fluorescence microscopy flow cytometry nuclear staining applications and monitoring cellular proliferation in biological investigations