Cycloheptathiophenes
![Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate, 96%](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-40106-13-6.jpg-250.jpg)
Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate, 96%
CAS: 40106-13-6 Molecular Formula: C12H17NO2S Molecular Weight (g/mol): 239.333 MDL Number: MFCD00216932 InChI Key: XTUHIGALMIGZST-UHFFFAOYSA-N Synonym: ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-4h,5h,6h,7h,8h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta-b thiophene-3-carboxylate,ethyl 2-amino-4,5,6,7,8-pentahydrocyclohepta 1,2-b thiophene-3-carboxylate,2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylic acid ethyl ester,ethyl 2-aminocyclohepta b thiophene-3-carboxylate,aronis24232,ethyl 2-aminocycloheptathiophene-3-carboxylate,2-amino-3-ethoxy-carbonyl-4,5-pentamethylenethiophene PubChem CID: 292644 IUPAC Name: ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate SMILES: CCOC(=O)C1=C(SC2=C1CCCCC2)N
Ketotifen fumarate, 99%
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.499 MDL Number: MFCD00079394 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N Synonym: ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro PubChem CID: 5282408 IUPAC Name: (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
Ketotifen Hydrogen Fumarate, EP, 98.5-101%, Spectrum™ Chemical
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.50 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N IUPAC Name: (2E)-but-2-enedioic acid; 2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.0³,⁷]tetradeca-1(14),3(7),4,10,12-pentaen-8-one SMILES: OC(=O)\C=C\C(O)=O.CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12
Ketotifen Fumarate 98.0+%, TCI America™
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.499 MDL Number: MFCD00079394 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N Synonym: ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro PubChem CID: 5282408 IUPAC Name: (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
Pizotifen 98.0+%, TCI America™
CAS: 15574-96-6 Molecular Formula: C19H21NS Molecular Weight (g/mol): 295.444 MDL Number: MFCD00864192 InChI Key: FIADGNVRKBPQEU-UHFFFAOYSA-N Synonym: 4-[9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene]-1-methylpiperidine, Sandomigran PubChem CID: 27400 ChEBI: CHEBI:50212 IUPAC Name: 4-(4,5-dihydrobenzo[1,2]cyclohepta[3,4-b]thiophen-10-ylidene)-1-methylpiperidine SMILES: CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1
Selleck Chemical LLC Fumarate hydratase-IN-1
Fumarate hydratase-IN-1 is a small molecule cell-permeable inhibitor of fumarate hydratase It induce alteration of TCA cycle metabolites modulation of cytosolic processes and substantial redox stress responses
Selleck Chemical LLC Fumarate hydratase-IN-1
Fumarate hydratase-IN-1 is a small molecule cell-permeable inhibitor of fumarate hydratase It induce alteration of TCA cycle metabolites modulation of cytosolic processes and substantial redox stress responses
Selleck Chemical LLC Fumarate hydratase-IN-1
Fumarate hydratase-IN-1 is a small molecule cell-permeable inhibitor of fumarate hydratase It induce alteration of TCA cycle metabolites modulation of cytosolic processes and substantial redox stress responses
Selleck Chemical LLC Fumarate hydratase-IN-1
Fumarate hydratase-IN-1 is a small molecule cell-permeable inhibitor of fumarate hydratase It induce alteration of TCA cycle metabolites modulation of cytosolic processes and substantial redox stress responses
Medchemexpress LLC VTP50469 fumarate | 2169919-29-1 | 99.8% | 804.93 | 1 ML
VTP50469 fumarate is a highly selective and orally active Menin-MLL interaction inhibitor. It demonstrates potent anti-leukemia activity by targeting MLL-rearranged and NPM1-mutant leukemia. This compound is intended for research use only.
- Potently inhibits Menin-MLL interaction with a Ki of 104 pM.
- Inhibits cell proliferation in MLL-rearranged and ALL cell lines.
- Induces apoptosis in MLL-r B cell ALL cell lines.
- Promotes differentiation in MLL-r AML cell lines.
- Displaces Menin from protein complexes.
- Effective in in vivo models of leukemia, improving survival.
TARGETMOL CHEMICALS INC Fumarate hydratase-IN-1 2MG
Also available in 1 mL, 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Fumarate hydratase-IN-1 is a cell-permeable fumarate hydratase inhibitor with antiproliferative activity and can be used to study cellular activity. Purity 98.96%
Medchemexpress LLC Ro 48-8071 Fumarate | 189197-69-1 | 99.1% | 564.44 | 1 ML
Ro 48-8071 is an inhibitor of Oxidosqualene cyclase (OSC) with an IC50 of approximately 6.5 nM. This compound is intended for research use only and is not sold for patient treatment. It has demonstrated efficacy in reducing cholesterol synthesis and inducing apoptosis in various cancer cell lines, as well as inhibiting tumor growth in vivo.
- Inhibits Oxidosqualene cyclase (OSC) with an IC50 of approximately 6.5 nM.
- Reduces cholesterol synthesis with an IC50 of approximately 1.5 nM in HepG2 cells.
- Significantly reduces viability of PC-3 prostate cancer cells.
- Induces apoptosis in LNCaP and C4-2 cell lines.
- Reduces AR protein expression and increases ERβ protein expression.
- Lowers LDL-C maximally by approximately 60% in hamsters.
- Significantly reduces in vivo tumor growth in mice.
Medchemexpress LLC Formoterol fumarate | 43229-80-7 | >99.9% | C19H24N2O4 . 1/2C4H4O4 | 1 ML
Formoterol fumarate is a selective β2-adrenoceptor agonist, demonstrating similar β2-adrenoceptor selectivity to Salbutamol and Terbutaline. This compound is known for its ability to abolish the contraction induced by Acetylcholine in bronchioles. It is commonly utilized in research applications for conditions such as chronic obstructive pulmonary disease and bronchial asthma.
- Selective β2-adrenoceptor agonist
- Abolishes acetylcholine-induced contraction in bronchioles
- Used in research for chronic obstructive pulmonary disease
- Utilized in research for bronchial asthma
Medchemexpress LLC Tesmilifene fumarate | 1185241-83-1 | MFCD09878272 | 99.9% | 399.48 g·mol⁻¹ | C23H29NO5 | 1 ML
Tesmilifene fumarate is the fumarate salt of tesmilifene, an H1C receptor antagonist and chemical sensitizer used in oncology research. Supplied as a 10 mM stock solution in DMSO (1 mL), it is intended for in vitro research applications including chemosensitization and cytotoxicity studies.
- Ready-to-use 10 mM stock solution in DMSO
- Concentrated 1 mL volume suitable for multiple assays
- High purity (99.9%) for research use
- Applicable to chemosensitization and cytotoxicity assays
- Provided with molecular weight and CAS identifiers for reporting
Apexbio Technology LLC (±)-Anatoxin A fumarate 1219922-30-1 1mg
( )-Anatoxin A fumarate (CAS 1219922-30-1) is a naturally occurring alkaloid isolated from freshwater cyanobacteria It functions as an agonist at nicotinic acetylcholine receptors exhibiting high binding affinity for rat brain 4 2 (K i 1 25 nM) and lower affinity for 7 (K i 1 84 M) subtypes In functional assays ( )-Anatoxin A fumarate induces dopamine release in rat striatal synaptosomes with an EC 50 of 134 nM This compound is utilized in neuroscience research to investigate cholinergic signaling and dopaminergic mechanisms in the central nervous system