Cycloheptathiophenes
Ketotifen Hydrogen Fumarate, EP, 98.5-101%, Spectrum™ Chemical
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.50 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N IUPAC Name: (2E)-but-2-enedioic acid; 2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-8-one SMILES: OC(=O)\C=C\C(O)=O.CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12
Ketotifen fumarate, 99%
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.499 MDL Number: MFCD00079394 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N Synonym: ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro PubChem CID: 5282408 IUPAC Name: (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
![Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate, 96%](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-40106-13-6.jpg-250.jpg)
Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate, 96%
CAS: 40106-13-6 Molecular Formula: C12H17NO2S Molecular Weight (g/mol): 239.333 MDL Number: MFCD00216932 InChI Key: XTUHIGALMIGZST-UHFFFAOYSA-N Synonym: ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-4h,5h,6h,7h,8h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta-b thiophene-3-carboxylate,ethyl 2-amino-4,5,6,7,8-pentahydrocyclohepta 1,2-b thiophene-3-carboxylate,2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylic acid ethyl ester,ethyl 2-aminocyclohepta b thiophene-3-carboxylate,aronis24232,ethyl 2-aminocycloheptathiophene-3-carboxylate,2-amino-3-ethoxy-carbonyl-4,5-pentamethylenethiophene PubChem CID: 292644 IUPAC Name: ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate SMILES: CCOC(=O)C1=C(SC2=C1CCCCC2)N
Pizotifen 98.0+%, TCI America™
CAS: 15574-96-6 Molecular Formula: C19H21NS Molecular Weight (g/mol): 295.444 MDL Number: MFCD00864192 InChI Key: FIADGNVRKBPQEU-UHFFFAOYSA-N Synonym: 4-[9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene]-1-methylpiperidine, Sandomigran PubChem CID: 27400 ChEBI: CHEBI:50212 IUPAC Name: 4-(4,5-dihydrobenzo[1,2]cyclohepta[3,4-b]thiophen-10-ylidene)-1-methylpiperidine SMILES: CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1
Ketotifen Fumarate 98.0+%, TCI America™
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.499 MDL Number: MFCD00079394 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N Synonym: ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro PubChem CID: 5282408 IUPAC Name: (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
Medchemexpress LLC Iron(II) fumarate (Ferrous fumarate) | 141-01-5 | 95.1% | 500 MG
Iron(II) fumarate is an orally effective active dietary supplement. It can alleviate metabolic damage and damage to silkworms caused by cypermethrin and can be used for research on iron deficiency anemia.
- Orally effective active dietary supplement.
- Can alleviate metabolic damage and damage to silkworms caused by cypermethrin.
- Can be used for research on iron deficiency anemia.
- In vitro, can restore metabolic pathway disruption caused by cypermethrin, enhance the tolerance and cell viability of BmN cells to cypermethrin.
- In vivo, can alleviate the damage of cypermethrin to silkworms.
- In vivo, can alter the intestinal morphology and microbiota of Yellow River carp, promoting the development of intestinal villi and increasing the thickness of the intestinal muscle layer.
TARGETMOL CHEMICALS INC Bedaquiline fumarate 25MG
Also available in 1 mL, 5 mg, 10 mg, 50 mg, 100 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. Bedaquiline fumarate (TMC207), a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections. It blocks the proton pump for ATP synthase of mycobacteria. It is the first member of a new class of drugs called diarylquinolines. Purity 99.77%
Apexbio Technology LLC Clemastine Fumarate 14976-57-9 10mM (in 1mL DMSO)
Clemastine Fumarate (CAS 14976-57-9) is a small molecule that functions as a selective antagonist of the histamine H1 receptor It demonstrates high affinity for the receptor with an inhibitory concentration (IC50) of 3 nM By blocking histamine H1 receptor-mediated signaling clemastine fumarate is utilized in research to study histaminergic pathways and allergic responses It is also employed to investigate the pharmacological modulation of H1 receptor activity in various cellular and in vivo models
Medchemexpress LLC Fesoterodine (fumarate) | 286930-03-8 | MFCD09835695 | ≥98% | 574.67 | 10 MG
Fesoterodine fumarate is an orally active, nonsubtype selective, competitive muscarinic receptor (mAChR) antagonist. It is used for the overactive bladder (OAB).
- Orally active
- Nonsubtype selective
- Competitive muscarinic receptor (mAChR) antagonist
- Targets mAChR
- Used for overactive bladder (OAB)
- Research areas include neurological disease, metabolic disease, and cancer
Medchemexpress LLC Fesoterodine fumarate | 286930-03-8 | 99.52% | C30H41NO7 | 5 MG
Fesoterodine fumarate | 286930-03-8 | 99.52% | C30H41NO7 | 5 MG
Medchemexpress LLC Vonoprazan Fumarate (TAK-438) | 881681-01-2 | MFCD18633280 | C21H20FN3O6S | 1 ML
Vonoprazan Fumarate (TAK-438) is a potent and orally active potassium-competitive acid blocker (P-CAB) developed for research into acid-related diseases such as gastroesophageal reflux disease and peptic ulcer disease. It functions as a proton pump inhibitor (PPI) and exhibits antisecretory activity.
- Potent and orally active potassium-competitive acid blocker (P-CAB)
- Proton pump inhibitor (PPI)
- Antisecretory activity
- Inhibits H+,K+-ATPase activity with an IC50 of 19 nM at pH 6.5
Medchemexpress LLC Fumarate hydratase-IN-2 sodium salt | 2070009-45-7 | MFCD00218071 | 98.7% | 440.47 g/mol | C25H25N2NaO4 | 50 MG
Fumarate hydratase-IN-2 sodium salt is a cell-permeable, competitive inhibitor of fumarate hydratase with a reported Ki of 4.5 μM. Supplied as a sodium salt solid, it is intended for biochemical and cellular studies probing fumarate hydratase activity and nutrient-dependent cytotoxicity.
- Cell-permeable competitive inhibitor of fumarate hydratase.
- Reported Ki 4.5 μM for fumarate hydratase.
- Molecular formula C25H25N2NaO4; molecular weight 440.47 g/mol.
- High purity (98.7%) in solid form.
- Available in multiple sizes, including 50 mg and 10 mM/1 mL solution.
Medchemexpress LLC 2-butenedioic acid (2e)-, 1-[2-(diethylamino)-2-oxoethyl] 4-methyl ester | 1208229-58-6 | 99.8% | 243.26 | 1 ML
Tepilamide fumarate is an oral fumaric acid ester that acts as a proagent of Monomethyl fumarate. It is used in the research of moderate to severe chronic plaque psoriasis and can enhance the effectiveness of oncolytic viruses. In vitro studies show that it makes 786-0 cancer cells more susceptible to infection by VSV∆51, leading to increased virus replication, and selectively promotes oncolytic virus infection in cancer cells without affecting healthy tissues.
- Oral fumaric acid ester
- Acts as a proagent of monomethyl fumarate
- Used in research of moderate to severe chronic plaque psoriasis
- Enhances the effectiveness of oncolytic viruses
- Increases susceptibility of cancer cells to viral infection
- Selectively promotes oncolytic virus infection in cancer cells
Cayman Chemical Monmethyl fumarate 250g
An active metabolite of dimethyl fumarate; an agonist of HCA2/GPR109A (EC50 = 9.4 µM); reduces neutrophil adhesion to endothelial cells stimulated with TNF, decreases CXCL2-directed neutrophil migration, and increases the expression of the Nrf2 target gene NQO1 in wild-type but not HCA2-/- macrophages; inhibits proliferation and induces differentiation in keratinocytes, as well as decreases TPA-induced levels of TNF-α in keratinocytes at 1 mM; reduces symptoms of EAE in mice at 1 mg/day
Medchemexpress LLC Ocifisertib fumarate | 1616420-30-4 | 99.3% | 650.72 Da | C37H38N4O7 | 5MG
Ocifisertib fumarate is the fumarate salt of Ocifisertib (CFI-400945), a potent, selective, orally bioavailable inhibitor of polo-like kinase 4 (PLK4) used as a research tool in oncology and cell biology to study centriole duplication and mitotic defects. Reported potency values support activity in biochemical and cellular assays.