Dioxolanes
Chemie Tek RMC-6236, 10mg
RMC-6236 is a First-in-Class, non-covalent, oral, potent, and RAS-Selective Tri-Complex RASMULTI(ON) Inhibitor with activity across a diverse spectrum of RAS mutants, including KRASG12V and KRASG12D (
Medchemexpress LLC Tulisokibart (PRA023), 10 mg, Humanized IgG1-κ Monoclonal Antibody
Tulisokibart (PRA023) is a humanized IgG1-κ monoclonal antibody targeting to TNFSF15/TL1A. Tulisokibart can be used to study a variety of inflammatory/fibrotic diseases, such as Crohn's Disease (CD).
Medchemexpress LLC Ertugliflozin L-pyroglutamic acid | 1210344-83-4 | 99.8% | 566.00 | 5 MG
Ertugliflozin L-pyroglutamic acid is a potent, selective, and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2), with an IC50 of 0.877 nM for h-SGLT2. It has potential for the treatment of type 2 diabetes mellitus.
- Potent, selective, and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2)
- Potential for the treatment of type 2 diabetes mellitus
- Demonstrates >2000-fold selectivity for SGLT2 inhibition (relative to SGLT1) in vitro
- Reveals a concentration-dependent glucosuria after oral administration to rats
Medchemexpress LLC HY-N0900 5mg Medchemexpress, Cimiracemoside D CAS:290821-39-5 Purity:>98%
Medchemexpress, HY-N0900 5mg Cimiracemoside D CAS:290821-39-5 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC Ertugliflozin S5413-25mg
Ertugliflozin (MK-8835 PF-04971729) is a potent and selective sodium-dependent glucose cotransporter 2 inhibitor with IC50 values of 0 877 nM for h-SGLT2 and 1000-fold higher for h-SGLT1
Medchemexpress LLC MedChemExpress Antibody, B7-H3 Target, Human, Anti-tumor Activity
This antibody targets B7-H3 and exhibits anti-tumor activity. It can be utilized for the synthesis of antibody-drug conjugates (ADCs) and is suitable for research in areas such as small cell lung cancer, relapsed or refractory osteosarcoma, and advanced solid tumors.
- Target: B7-H3
- Exhibits anti-tumor activity
- Can be studied for small cell lung cancer, relapsed or refractory osteosarcoma, and advanced solid tumors
- Human IgG1 kappa isotype
- Human species reactivity
- Applications include ELISA, FACS, and functional assay
- Unconjugated format
- Can be reconstituted/diluted with sterile PBS or saline
- Immobilized huB7H3-His can bind Risvutatug with an EC50 of 13.41 ng/mL
- Purity: 99.57%
- Molecular weight: 143.94 kDa
- Appearance: liquid
- Color: colorless to light yellow
Selleck Chemical LLC SRI-37330 HCl-E1272-5MG
SRI-37330 HCl(EX-A5854) an anti-diabetic drug is an orally bioavailable inhibitor of thioredoxin-interacting protein (TXNIP) with an IC50 of 0 64 M for TXNIP expression in INS-1 cells Its treatment inhibits glucagon secretion and function decreases hepatic glucose production and reverses hepatic steatosis
TARGETMOL CHEMICALS INC ND-322 HCL 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ND-322 HCl (ND 322 Hydrochloride) is a selective inhibitor of MT1-MMP and MMP2 and reduces in vitro melanoma cell growth migration and invasion. purity: 98%