Dithiolanes
Apexbio Technology LLC MRT-2359-1MG
MRT-2359 (CAS No 2803881-11-8) is a research compound in the biomedical field originating from studies of cellular signal transduction pathways It functions primarily by modulating specific protein targets involved in disease progression utilizing mechanisms such as enzyme inhibition or receptor modulation Its activity is typically observed in the nanomolar to low micromolar range making it effective in in vitro experiments Common applications include studies in various cell models animal studies for disease modeling and high-throughput drug screening platforms Experimental concentrations typically depend on the specific research design
Selleck Chemical LLC MRT-2359-E1427-5MG
MRT-2359 is a potent degrader of GSPT1 It exhibits anti-tumor activity in non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) cells
Apexbio Technology LLC Fasudil (HA-1077) HCl 105628-07-7 500mg
Fasudil HA-1077 HCl (CAS 105628-07-7) is a small-molecule inhibitor targeting Rho-associated protein kinase (ROCK) a serine/threonine kinase It is designed to inhibit ROCK thereby regulating cellular processes such as proliferation migration and apoptosis Fasudil HA-1077 HCl exerts its biological activity primarily through ROCK inhibition In cell-based studies Fasudil inhibits proliferation and migration and promotes apoptosis in cancer cell models including bladder carcinoma (5637 UM-UC-3) and oral squamous cell carcinoma (SCC-4) its ROCK inhibitory activity shows an IC50 value of approximately 0 74 M Based on these pharmacological properties Fasudil HA-1077 HCl holds research potential in oncology and disease models involving ROCK-mediated signaling
eMolecules 1077-28-7 | ?-Lipoic Acid | Medchem Express | MFCD00005474 | 206.320 | C8H14O2S2 | 98.000 | OC(=O)CCCCC1CCSS1 | 1g | 841054629
?-Lipoic Acid | Medchem Express | 1077-28-7 | MFCD00005474 | 206.320 | C8H14O2S2 | 98.000 | OC(=O)CCCCC1CCSS1 | 1g | 841054629
Medchemexpress LLC (R)-(+)-α-Lipoic acid | 1200-22-2 | MFCD01631142 | 99.8% | 206.33 | 25 MG
Lipoic acid (Standard) is the analytical standard of Lipoic acid, intended for research and analytical applications. It is an antioxidant and an essential cofactor of mitochondrial enzyme complexes. The (R)-(+)-α-Lipoic acid form is more effective than racemic Lipoic acid and is the form biosynthesized in humans. It plays a vitamin-like role in metabolism and is nutritionally and therapeutically preferred as an antioxidant.
- Suitable for qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Essential cofactor for mitochondrial enzyme complexes.
- Plays a vitamin-like role in metabolism.
- Nutritionally and therapeutically preferred as an antioxidant.
Medchemexpress LLC Lipoic acid (Standard) | 1200-22-2 | 99.8% | 206.33 | 100 MG
Lipoic acid (Standard) is the analytical standard of Lipoic acid, intended for research and analytical applications. It acts as an antioxidant and is an essential cofactor of mitochondrial enzyme complexes. The (R)-(+)-α-Lipoic acid is more effective than racemic Lipoic acid. This compound is used as a reference standard in qualitative, quantitative, and methodological research experiments.
- Acts as an antioxidant
- Serves as an essential cofactor of mitochondrial enzyme complexes
- More effective than racemic Lipoic acid
- Used as a reference standard in qualitative, quantitative, and methodological research experiments
- Applicable in techniques such as HPLC, GC, and MS
Medchemexpress LLC Α-Lipoic acid (Standard) | 1077-28-7 | 206.33 | 100 MG
Α-Lipoic acid (Standard) | 1077-28-7 | 206.33 | 100 MG
Medchemexpress LLC 1,2-Dithiolane-3-pentanoic acid | 1077-28-7 | 206.33 | 10 G
1,2-Dithiolane-3-pentanoic acid | 1077-28-7 | 206.33 | 10 G
Medchemexpress LLC R-(+)-α-lipoic acid | 1200-22-2 | MFCD01631142 | 99.4% | 206.33 | C8H14O2S2 | 10 MG
Analytical standard of (R)-(+)-α-lipoic acid intended for research and analytical applications such as HPLC, GC, and MS. It is used as a quantitative and qualitative reference material for method development, calibration, and validation in biochemical and pharmaceutical analysis.
- High purity suitable for analytical assays (99.36%).
- Defined chemical identity for accurate reference (C8H14O2S2, MW 206.33).
- Compact 10 mg packaging for analytical use and method validation.
- Stable under recommended storage; consult the certificate of analysis for handling.
Medchemexpress LLC α-Lipoic Acid | 1077-28-7 | MFCD00005474 | 206.33 | 5 G
α-Lipoic Acid (Thioctic acid) is an antioxidant and an essential cofactor of mitochondrial enzyme complexes. It inhibits NF-κB-dependent HIV-1 LTR activation and induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells. It can also be used with CPUL1 to construct the self-assembled nanoaggregate CPUL1-LA NA, which demonstrates improved antitumor efficacy compared to CPUL1.
- Antioxidant
- Essential cofactor of mitochondrial enzyme complexes
- Inhibits NF-κB-dependent HIV-1 LTR activation
- Induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells
- Can be used to construct self-assembled nanoaggregates with improved antitumor efficacy
Medchemexpress LLC Alpha-Lipoic acid (Standard) | 1077-28-7 | 206.33 | 25 MG
Alpha-Lipoic Acid (Standard) is the analytical standard of α-Lipoic Acid, intended for research and analytical applications. It functions as an antioxidant and is an essential cofactor of mitochondrial enzyme complexes. It inhibits NF-κB-dependent HIV-1 LTR activation and induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells. It can also be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, demonstrating improved antitumor efficacy compared to CPUL1.
- Used as a reference standard in qualitative, quantitative, and methodological research experiments, including HPLC, GC, and MS.
- Inhibits NF-κB-dependent HIV-1 LTR activation.
- Induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells.
- Essential cofactor of mitochondrial enzyme complexes.
Medchemexpress LLC 4-Hydroxyisophthalic acid | 636-46-4 | 99.51% | C8H6O5 | 100 MG
4-Hydroxyisophthalic acid is a compound known for its antioxidant properties. It functions by activating key antioxidant enzymes such as catalase (CAT) and superoxide dismutase (SOD), and by scavenging free radicals. This compound also enhances neuronal function through the activation of AChE and BChE, which can lead to improvements in neurobehavioral defects induced by Tau protein and can ameliorate circadian rhythm disorders.
- Activates antioxidant enzymes (catalase CAT and superoxide dismutase SOD)
- Scavenges free radicals
- Exhibits antioxidant properties
- Activates AChE and BChE
- Enhances neuronal function
- Improves Tau-induced neurobehavioral defects
- Ameliorates circadian rhythm disorders in fruit flies
Medchemexpress LLC 4-Hydroxyisophthalic acid | 636-46-4 | 99.5% | C8H6O5 | 50 MG
4-Hydroxyisophthalic acid activates antioxidant enzymes (such as catalase CAT and superoxide dismutase SOD), scavenges free radicals, and exhibits antioxidant properties. It also activates AChE and BChE, enhances neuronal function, improves Tau-induced neurobehavioral defects, and ameliorates cognitive defects and circadian rhythm disorders in fruit flies.
- Activates antioxidant enzymes (catalase and superoxide dismutase)
- Scavenges free radicals
- Exhibits antioxidant properties
- Activates AChE and BChE
- Enhances neuronal function
- Improves Tau-induced neurobehavioral defects
- Ameliorates cognitive defects
- Ameliorates circadian rhythm disorders in fruit flies