Dithiolanes
Sigma Aldrich Fine Chemicals Biosciences Thioctic acid for system s
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
Sigma Aldrich Fine Chemicals Biosciences (R)-(+)-alpha-Lipoic acid >=98.0% (HPLC) | 1200-22-2 | MFCD01631142 | 500MG
(R)-(+)-alpha-Lipoic acid >=98.0% (HPLC) | Purity: >=98.0% (HPLC) | Mol Wt: 206.33 | 1200-22-2 | MFCD01631142 | 500MG
Selleck Chemical LLC ()-a-Lipoic acid S3998-1g
( )- -Lipoic acid ((R)-( )- -Lipoic acid -Lipoic acid Alpha-Lipoic acid) a physiological form of thioctic acid is a strong antioxidant that relieves diabetic neuropathic symptoms It shows superior antioxidative effects to its racemate R( )- -lipoic acid is an essential cofactor of mitochondrial enzyme complexes R( )- -lipoic acid inhibits NF- B-dependent HIV-1 LTR activation
Cayman Chemical R-a-LIpoIc AcId 10g
A cyclic disulfide antioxidant; acts as a cofactor in 2-oxo dehydrogenase complex reactions and is reduced to DHLA; decreases serum levels of MDA and increases the activity of SOD and T-AOC in a mouse model of D-galactose-induced accelerated senescence at 100 mg/kg per day; reduces the escape latency in the Morris water maze compared to both D-galactose and vehicle control groups and rescues decreases in neural progenitor cell proliferation in the hippocampal dentate gyrus at 100 mg/kg per day
Medchemexpress LLC Alpha-lipoic acid | 1077-28-7 | MFCD00005474 | 10 MG
Analytical standard of α-lipoic acid supplied as a 10 mg reference material for research and analytical applications. Suitable for assay, calibration, and analytical method development. CAS number 1077-28-7; molecular weight 206.33; molecular formula C8H14O2S2.
- Supplied as a 10 mg reference material for analytical use.
- Suitable for assay calibration and method validation.
- Provides molecular and CAS identification for traceability.
- Intended for research and analytical applications, including method development.
Abcam D,L-Thioctic acid (DL-alpha-Lipoic acid), Non-specific free radical scavenger, 25G
MW 206.3 Da, Purity >98%. Non-specific free radical scavenger. Prevents lipid peroxidation and promotes mitochondrial permeability transition in vitro. Anti-oxidant. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC MRT-2359 | 2803881-11-8 | C22H17F4N3O6 | 25 MG
MRT-2359 is a potent, orally active, and selective GSPT1 depressant (IC50: >30 nM and <300 nM) that specifically induces apoptosis dependent on protein translation. It exhibits significant anti-proliferative activity in various cancer cell lines, particularly MYC-driven cell lines like non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) with high N-Myc or L-Myc expression, making it suitable for cancer research.
- Potent, orally active, and selective GSPT1 depressant
- Specifically induces apoptosis dependent on protein translation
- Significant anti-proliferative activity in MYC-driven cancer cell lines
- Effective against non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC)
- Inhibits the growth of drug-resistant NSCLC and SCLC cells
- Reduces N-Myc protein expression and tumor size
- Active against prostate cancer
Medchemexpress LLC 4-Hydroxyisophthalic acid | 636-46-4 | 99.5% | C8H6O5 | 10 MM 1 ML
This compound activates antioxidant enzymes (such as catalase and superoxide dismutase) and scavenges free radicals, demonstrating antioxidant properties. It also activates AChE and BChE, which enhances neuronal function and improves neurobehavioral defects. Additionally, it can ameliorate cognitive defects and circadian rhythm disorders.
- Activates antioxidant enzymes and scavenges free radicals.
- Exhibits antioxidant properties.
- Enhances neuronal function.
- Improves neurobehavioral defects.
- Ameliorates cognitive defects and circadian rhythm disorders.
Medchemexpress LLC Isophthalic acid | 121-91-5 | 100.0% | 166.13 | 50 G
Isophthalic acid is a biological material or organic compound extensively utilized in life science research.
- Purity of 99.96%
- Molecular weight of 166.13
- Formula C8H6O4
- CAS number 121-91-5
- Solid appearance
- White to off-white color
- Ships at room temperature
- Powder storage at -20°C for 3 years, 4°C for 2 years
- Storage in solvent at -80°C for 6 months, -20°C for 1 month
- Solubility of 200 mg/mL in DMSO
Chem-Impex International, Inc. 5-Aminoisophthalic acid hydrate | MFCD09037349 | 25G
5-Aminoisophthalic acid hydrate, MFCD09037349, 25G
Apexbio Technology LLC Fasudil (HA-1077) HCl 105628-07-7 500mg
Fasudil HA-1077 HCl (CAS 105628-07-7) is a small-molecule inhibitor targeting Rho-associated protein kinase (ROCK) a serine/threonine kinase It is designed to inhibit ROCK thereby regulating cellular processes such as proliferation migration and apoptosis Fasudil HA-1077 HCl exerts its biological activity primarily through ROCK inhibition In cell-based studies Fasudil inhibits proliferation and migration and promotes apoptosis in cancer cell models including bladder carcinoma (5637 UM-UC-3) and oral squamous cell carcinoma (SCC-4) its ROCK inhibitory activity shows an IC50 value of approximately 0 74 M Based on these pharmacological properties Fasudil HA-1077 HCl holds research potential in oncology and disease models involving ROCK-mediated signaling