Furans
Apexbio Technology LLC PYR-41,10mg CAS# 418805-02-4
Ubiquitylation is catalyzed by the sequential action of ubiquitinactivating enzyme (E1), a ubiquitin-conjugating enzyme (E2) and a ubiquitin protein ligase (E3). Ubiquitylation is essential to numerous cellular and developmental processes, including protein quality control, growth, apoptosis, antigen presentation, DNA repair, and signal transduction. PYR-41, 4[4-(5-nitro-furan-2-ylmethylene)-3,5-dioxo-pyrazolidin-1-yl]-benzoic acid ethyl ester, is a selective inhibitor of Ubiquitin-Activating Enzyme (E1).In vitro: In addition to blocking ubiquitylation, PYR-41 was found to increase total sumoylation in cells. PYR-41 could attenuate cytokine-mediated nuclear factor-KBactivation. This correlated with inhibition of nonproteasomal ubiquitylation of TRAF6, which is important to IKBkinase activation. Other sizes are also available. Please inqury us for quote.
Medchemexpress LLC HY-B1336 100mg Medchemexpress, Furazolidone CAS:67-45-8 Purity:>98%
Medchemexpress, HY-B1336 100mg Furazolidone CAS:67-45-8 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-101090 5mg Medchemexpress, KYA1797K CAS:1956356-56-1 Purity:>98%
Medchemexpress, HY-101090 5mg KYA1797K CAS:1956356-56-1 KYA1797K is a potent and selective Wnt/β-catenin inhibitor with an IC 50 of 0.75 µM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-19726 5mg Medchemexpress, NSC59984 CAS:803647-40-7 Purity:>98%
Medchemexpress, HY-19726 5mg NSC59984 CAS:803647-40-7 NSC59984 induces mutant p53 protein degradation via MDM2 and the ubiquitin-proteasome pathway. NSC59984 acts by targeting GOF-mutant p53 and stimulates p73 to restore the p53 pathway signaling. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-15951 5mg Medchemexpress, ML167 CAS:1285702-20-6 Purity:>98%
Medchemexpress, HY-15951 5mg ML167 CAS:1285702-20-6 ML167 is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor with IC50 of 136 nM, >10-fold selectivity for closely related kinases Clk1, Clk2, Clk3 and Dyrk1A/1B. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-100578 5mg Medchemexpress, AGK2 CAS:304896-28-4 Purity:>98%
Medchemexpress, HY-100578 5mg AGK2 CAS:304896-28-4 AGK2 is a selective SIRT2 inhibitor with IC 50 of 3.5 μM. AGK2 can also inhibit SIRT1 and SIRT3 with IC 50 of 30 and 91 μM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-U00213 5mg Medchemexpress, Furaprofen CAS:67700-30-5 Purity:>98%
Medchemexpress, HY-U00213 5mg Furaprofen CAS:67700-30-5 Furaprofen (R803) is an effective HCV replication inhibitor. Furaprofen (R803) is substantially more potent against genotype 1a and 1b replicons (EC50, ~30 nM) than against the genotype 2a replicon (EC50, ~1,000 nM). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-18600A 5mg Medchemexpress, Azimilide (Dihydrochloride) CAS:149888-94-8 Purity:>98%
Medchemexpress, HY-18600A 5mg Azimilide (Dihydrochloride) CAS:149888-94-8 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-15701A 5mg Medchemexpress, (Z)-Leukadherin-1 CAS:2055362-72-4 Purity:>98%
Medchemexpress, HY-15701A 5mg (Z)-Leukadherin-1 CAS:2055362-72-4 (Z)-Leukadherin-1 (ADH-503 free base) is an orally active and allosteric CD11b agonist. (Z)-Leukadherin-1 leads to the repolarization of tumor-associated macrophages, reduction in the number of tumor-infiltrating immunosuppressive myeloid cells, and enhances dendritic cell responses. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-12542A 100mg Medchemexpress, Dantrolene (sodium hemiheptahydrate) CAS:24868-20-0 Purity:>98%
Medchemexpress, HY-12542A 100mg Dantrolene (sodium hemiheptahydrate) CAS:24868-20-0 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-W012946 100mg Medchemexpress, 2-Furoic acid CAS:88-14-2 Purity:>98%
Medchemexpress, HY-W012946 100mg 2-Furoic acid CAS:88-14-2 2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation [1] . 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats [2] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Sigma Aldrich 1-Aminopyrene
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 2-Mercaptophenol
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 4-(2-Chlorophenoxy)butanoic acid
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 6-Methyl-3(2H)-pyridazinone
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.