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Organic bicyclic compounds that consist of two fused furan rings; furan rings consist of a five-membered ring with four carbon atoms, one oxygen atom, and two double bonds.
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Most potent member of the ginkgolide family of PAF antagonists. Ginkgolide B accelerates PAF hydrolysis by promoting PAF-AH I α2 homodimer activity. Inhibits PAF-induced PMNL chemotaxis (IC50=490 nM). Orally effective against PAF-induced bronchospasm. Alternative name: BN 52021. Purity: ≥90% (HPLC). Solubility: Soluble in DMSO (25mg/ml) or 100% ethanol (2mg/ml). Long Term Storage: -20°C.
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Liguiritigenin-7-O-D-apiosyl-4'-O-D-glucoside is a flavanone glycoside isolated from Glycyrrhizia inflata and provided as a solid research reagent for analytical and biochemical studies.
Flavanone glycoside isolated from Glycyrrhizia inflata.
Molecular formula C26H30O13.
Molecular weight 550.51 g·mol⁻¹.
CAS number 199796-12-8.
Purity 99.6% by supplier analysis.
Physical form solid, supplied in small milligram quantities.
Storage: 4°C protected from light; in solvent -80°C (6 months), -20°C (1 month).
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This compound is an orally active small-molecule inhibitor of tumor necrosis factor-alpha (TNF-α) release that inhibits p38 phosphorylation and can reduce apoptosis; it is used in research on inflammatory signaling, HIV, and neurological disease models.
Orally active TNF-α release inhibitor.
Inhibits p38 phosphorylation and modulates apoptosis.
Applicable to research in inflammatory signaling, HIV, and neurological disease models.
Solid, white to off-white appearance suitable for lab handling.
High purity suitable for research applications.
Store powder at -20°C; solvent storage conditions available.
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CPI-1189 is an orally active TNF-α release inhibitor that suppresses p38 MAP kinase phosphorylation and has demonstrated anti-apoptotic activity. It is used in preclinical research on inflammatory signaling, HIV, and neurological disease models.
Orally active TNF-α release inhibitor suitable for in vitro and in vivo studies.
Inhibits p38 phosphorylation, useful for signaling pathway research.
Demonstrated anti-apoptotic activity in relevant models.
High purity (99.82%) solid, white to off-white powder.
Stable when stored at -20°C as powder and under recommended solvent conditions.
Available in small research pack sizes to support dose-ranging experiments.
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MRS2179 tetrasodium hydrate is a competitive P2Y1 receptor antagonist used as a research reagent to inhibit P2Y1-mediated responses, including platelet aggregation. It is supplied as a white to off-white solid with high purity and is intended for laboratory research use only; store sealed and protected from moisture.
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Isosorbide dinitrate is a nitric oxide (NO) donor used as a research reagent and analytical standard for studies of vasodilation, myocardial infarction, and cardiac remodeling. It is supplied as a high-purity solid suitable for in vitro and analytical applications.
High purity (99.9%).
Chemical formula C6H8N2O8; molecular weight 236.14.
CAS number 87-33-2.
Soluble in DMSO (100 mg/mL); ultrasonic agitation recommended.
Store protected from light at 4°C; in solvent, -80°C up to 6 months or -20°C up to 1 month.
Available as solid packs (5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg) and as 10 mM solutions in DMSO.
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