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Filtered Search Results
Medchemexpress LLC VRT-534 | 926664-32-6 | 98.3% | 497.99 | 5 MG
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VRT-534 is a chemical chaperone (Compound 3) that targets connexin 26 (Cx26), demonstrating dose-responsive binding to recombinant wild-type Cx26 and mutant Cx26 K188N with EC50s of 19 and 5 μM, respectively. It is useful in research concerning hearing impairment. In vitro studies indicate that VRT-534 (50 μM; 24h) restores the vitality of HeLa cells and shows restorative effects on Cx26 mutants L90P and F161S in HeLa cells.
- Targets connexin 26 (Cx26)
- Exhibits dose-responsive binding to recombinant wild-type Cx26 and mutant Cx26 K188N
- Useful in research related to hearing impairment
- Restores vitality of HeLa cells
- Shows restorative effect on Cx26 mutants L90P and F161S in HeLa cells
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Medchemexpress LLC VRT-534 | 926664-32-6 | 98.3% | 497.99 | 50 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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VRT-534 (Compound 3) is a chemical chaperone that targets connexin 26 (Cx26). It shows dose-responsive binding to recombinant WT Cx26 and mutant Cx26 K188N with EC50s of 19 and 5 μM, respectively.
- Can be used in research related to hearing impairment.
- Restores the vitality of HeLa cells.
- Had a restorative effect on Cx26 mutants L90P and F161S in Hela cells.
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eMolecules 75433-73-7 | 3,4-Dihydro-2H-quinoline-1,2-dicarboxylic acid 1-benzyl ester | J & W PharmLab LLC | MFCD01925258 | 311.337 | C18H17NO4 | 96.000 | OC(=O)C1CCc2ccccc2N1C(=O)OCc1ccccc1 | 5g | 289356771
3,4-Dihydro-2H-quinoline-1,2-dicarboxylic acid 1-benzyl ester | J & W PharmLab LLC | 75433-73-7 | MFCD01925258 | 311.337 | C18H17NO4 | 96.000 | OC(=O)C1CCc2ccccc2N1C(=O)OCc1ccccc1 | 5g | 289356771
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eMolecules 99361-32-7 | methyl 1,8-naphthyridine-4-carboxylate | J & W PharmLab LLC188.186 | C10H8N2O2 | 96.000 | COC(=O)c1ccnc2ncccc12 | 50mg | 495795411
methyl 1,8-naphthyridine-4-carboxylate | J & W PharmLab LLC | 99361-32-7188.186 | C10H8N2O2 | 96.000 | COC(=O)c1ccnc2ncccc12 | 50mg | 495795411
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STA Pharmaceutical 2'-F U amidite | 100 g | CAS 146954-75-8 | MDL MFCD11113919
2'-F U amidite is a Amidite reagent (Subcategory: 2'-F Series) sold by WuXi TIDES. Offered in 100 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 146954-75-8
- MDL: MFCD11113919
- InChIKey: HQHQPAYRJJMYQX-DJTPZYMWSA-N
- Molecular Weight: 748.789165161
- Molecular Formula: C39H46FN4O8P
- Purity: ≥99%
- Container Type: 500 mL HDPE
- Pack Size: 100 g
- Net Weight: 100 g
- Gross Weight: 160.5 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: COC1=CC=C(C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@H]4O[C@@H](N5C=CC(NC5=O)=O)[C@@H]([C@@H]4OP(N(C(C)C)C(C)C)OCCC#N)F)C=C1
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eMolecules 7570-49-2 | 5-Amino-2-methylindole | Combi-Blocks | MFCD02093426 | 146.193 | C9H10N2 | 95.000 | Cc1cc2cc(N)ccc2[nH]1 | 1g | 117556992
5-Amino-2-methylindole | Combi-Blocks | 7570-49-2 | MFCD02093426 | 146.193 | C9H10N2 | 95.000 | Cc1cc2cc(N)ccc2[nH]1 | 1g | 117556992
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Ik-930 | 2563892-44-2 | MFCD34755308 | 99.4% | 424.44 g/mol | C19H19F3N4O2S | 10 MG
Small and Specialty Supplier Partner
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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IK-930 is a small-molecule TEAD inhibitor reported as potent and orally active, with a cellular EC50 <0.1 μM. It is supplied as a solid research reagent for biochemical and cellular studies targeting TEAD-dependent transcription and Hippo pathway biology.
- Potent, orally active TEAD inhibitor (EC50 <0.1 μM).
- High purity, 99.39%.
- Molecular weight 424.44 g/mol.
- Chemical formula C19H19F3N4O2S.
- Solid powder form for storage and formulation flexibility.
- Storage: powder -20°C (up to 3 years) or 4°C (up to 2 years).
- CAS number 2563892-44-2 for unambiguous identification.
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eMolecules 1210-39-5 | 3,3-Diphenylacrylaldehyde | MFCD00006996 | 5g
ChemScene | Propargyl-PEG4-Br | 100mg | 598463204 | CS-0109323 | 1308299-09-3 | MFCD28950764 | 295.173 | C11H19BrO4
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eMolecules 254-79-5 | 1,5-Naphthyridine | Ambeed | MFCD00039727 | 130.15 | C8H6N2 | 98 | c1cnc2cccnc2c1 | 1g | 491168597
Ambeed | Ethyl 2-bromovalerate | 25g | 628567075 | A1483653 | 615-83-8 | MFCD00000159 | 209.083 | C7H13BrO2
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Accela Chembio Inc Ethyl 3-pyrazolecarboxylate | 5g | 5932-27-4 | MFCD00159643 | 97+% | Shelf Life: 1260 Days | Light Sensitive
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Ethyl 3-pyrazolecarboxylate | 5g | 5932-27-4 | MFCD00159643 | 97+% | Shelf Life: 1260 Days | Light Sensitive
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eMolecules 270082-22-9 | (S)-2-Tetrahydroisoquinoline acetic acid hydrochloride | Chem-Impex | MFCD03002606 | 227.690 | C11H14ClNO2 | 98.000 | Cl.OC(=O)CC1Cc2ccccc2CN1 | 5g | 322124532
(S)-2-Tetrahydroisoquinoline acetic acid hydrochloride | Chem-Impex | 270082-22-9 | MFCD03002606 | 227.690 | C11H14ClNO2 | 98.000 | Cl.OC(=O)CC1Cc2ccccc2CN1 | 5g | 322124532
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eMolecules 206986-92-7 | Cobalt(ii) hexafluoroacetylacetonate hydrate | Combi-Blocks | MFCD00150649 | 491.051 | C10H4CoF12O5 | 95.000 | O.[Co++].[O-]\C(=C/C(=O)C(F)(F)F)C(F)(F)F.[O-]\C(=C/C(=O)C(F)(F)F)C(F)(F)F | 5g | 537624433
Cobalt(ii) hexafluoroacetylacetonate hydrate | Combi-Blocks | 206986-92-7 | MFCD00150649 | 491.051 | C10H4CoF12O5 | 95.000 | O.[Co++].[O-]\C(=C/C(=O)C(F)(F)F)C(F)(F)F.[O-]\C(=C/C(=O)C(F)(F)F)C(F)(F)F | 5g | 537624433
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eMolecules 124750-59-0 | 2-Propyl-1H-imidazole-4,5-dicarboxylic acid dimethyl ester | MFCD09743546 | 5g
Medchem Express | Terconazole-d4 | 1mg | 784544374 | HY-B1790S | 1398065-50-3 | 536.490 | C26H31Cl2N5O3
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Apexbio Technology LLC Imidazole 288-32-4 5g
Imidazole (CAS 288-32-4) is an aromatic heterocycle characterized by a five-membered ring structure containing two nitrogen atoms at the 1 and 3 positions Imidazole serves as a prototypical scaffold in medicinal chemistry notable for its role in enzyme binding and metal ion coordination due to its electron-rich nitrogen atoms It is commonly utilized in biochemical research including the study of enzyme mechanisms and as a buffer component in protein purification protocols Imidazole derivatives are also investigated as modulators of various biological targets supporting its broad relevance in pharmacological and biochemical studies
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eMolecules 59237-53-5 | Methyl 6-chloro-5-nitronicotinate | Ambeed | MFCD01928341 | 216.580 | C7H5ClN2O4 | 97.000 | COC(=O)c1cnc(Cl)c(c1)[N+]([O-])=O | 250mg | 552599161
Methyl 6-chloro-5-nitronicotinate | Ambeed | 59237-53-5 | MFCD01928341 | 216.580 | C7H5ClN2O4 | 97.000 | COC(=O)c1cnc(Cl)c(c1)[N+]([O-])=O | 250mg | 552599161
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