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Filtered Search Results
Medchemexpress LLC AM-Imidazole-PA-Boc | 2357108-99-5 | 98.2% | 25 MG
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AM-Imidazole-PA-Boc is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTAC IRAK4 degrader-1. This product is for research use only and not intended for sale to patients.
- Alkyl chain-based PROTAC linker
- Used in the synthesis of PROTAC IRAK4 degrader-1
- For research use only
- Not intended for sale to patients
- CAS number: 2357108-99-5
- Molecular weight: 254.33
- Formula: C12H22N4O2
- Appearance: Oil
- Color: Off-white to gray
- Purity: 98.22%
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Ethanethiol, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]- (hydrochloride) | 95.0% | 25 MG
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HS-PEG3-CH2CH2NH2 hydrochloride is a PEG-based PROTAC linker used in the synthesis of PROTACs. These compounds are designed to exploit the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- PEG-based PROTAC linker
- Utilized for the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Designed for selective degradation of target proteins
- Intended for research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 1111638-05-1 | 6-Bromo-2-methylimidazo[1,2-a]pyrimidine | Synthonix - Stock | MFCD12024554 | 212.050 | C7H6BrN3 | 97.000 | Cc1cn2cc(Br)cnc2n1 | 5g | 505079491
6-Bromo-2-methylimidazo[1,2-a]pyrimidine | Synthonix - Stock | 1111638-05-1 | MFCD12024554 | 212.050 | C7H6BrN3 | 97.000 | Cc1cn2cc(Br)cnc2n1 | 5g | 505079491
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Alkali Scientific Imidazole [Glyoxaline] [1,3 Diaza 2 ,4 cyclopentadiene], 50 Grams
Imidazole [Glyoxaline] (1,3-Diaza 2,4-Cyclopentadiene) is a high-purity laboratory reagent widely used in organic chemistry and biochemistry. It is a versatile heterocyclic compound that serves as a key building block in synthetic chemistry, particularly in the preparation of pharmaceuticals, agrochemicals, and other fine chemicals. Its unique structure, with nitrogen atoms in the ring, makes it an excellent ligand in coordination chemistry and a critical intermediate in the synthesis of various biologically active compounds. This reagent is especially valuable in the synthesis of imidazole derivatives used in enzyme catalysis, pharmaceutical formulations, and as a stabilizer in certain chemical reactions.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Alkali Scientific Uracil, 1 Kg
Uracil is a pyrimidine nucleobase commonly used in molecular biology applications, particularly for nucleic acid synthesis and research. This laboratory-grade compound is essential for studying RNA synthesis, as it is one of the four nucleotide bases that make up RNA molecules. Uracil is also used in various biochemical assays and experiments, including genetic studies and RNA sequencing. In addition, it plays a critical role in studies of nucleic acid metabolism and the synthesis of synthetic oligonucleotides. The 1kg quantity of uracil offers researchers a sufficient supply for long-term projects and high-throughput studies, making it an essential reagent in molecular biology and biochemistry.
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Medchemexpress LLC Complement C3 protein, cynomolgus (HEK293, His) | >90.0% | 5 UG
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Recombinant complement C3 protein derived from cynomolgus macaque and expressed in HEK293 cells with a C-terminal His tag. It is suitable for studies of complement activation, C3 processing, and complement-mediated inflammation, and for use as a reagent in biochemical and cell-based assays.
- Cynomolgus origin for macaque-specific studies.
- Expressed in HEK293 cells to retain mammalian post-translational modifications.
- C-terminal His tag enables purification and detection.
- Purity greater than 90% as determined by reducing SDS-PAGE.
- Available in small research sizes for assay development.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Fl118-C3-O-C-amide-C-NH2-d5 formate | 2821769-41-7 | 587.59 g/mol | C28H25D5N4O10 | 10 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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FL118-C3-O-C-amide-C-NH2-d5 formate is a deuterium-labeled formate salt of an FL118-derived ADC linker intended for research use as a tracer, internal standard, or building block in antibody-drug conjugate synthesis. It is supplied in small milligram quantities for analytical and synthetic workflows.
- Deuterium-labeled (d5) tracer for quantitative analyses.
- Formate salt for improved handling and solubility.
- Suitable as an internal standard for NMR, GC-MS, and LC-MS methods.
- Available in milligram-scale quantities for research applications.
- Molecular formula C28H25D5N4O10 and molecular weight 587.59 g/mol.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Naringenin triacetate | 3682-04-0 | MFCD00706050 | >98.0% | 398.36 | C21H18O8 | 10 MG
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Naringenin triacetate is a plant-derived flavonoid research reagent reported to bind the first bromodomain of BRD4 (BRD4 BD1). It is provided as a solid for laboratory in-vitro studies and is for research use only, not for human or animal administration.
- Reported binder of BRD4 first bromodomain (BRD4 BD1).
- CAS number 3682-04-0.
- Molecular formula C21H18O8; molecular weight 398.36.
- Available in small research quantities, e.g., 10 mg.
- Purity reported >98% by HPLC from distributor sources.
- Intended for in-vitro research use only.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC 2-Aminopurine-O-Ph-NHCO-C3-COOH hydrochloride | 95.3% | 420.85 | C18H21ClN6O4 | 5 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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2-Aminopurine-O-Ph-NHCO-C3-COOH hydrochloride is a white to off-white solid used as the carboxylic acid precursor in the synthesis of activated esters. It is supplied with analytical purity and is intended for research and synthetic chemistry applications where a defined intermediate is required. Molecular formula C18H21ClN6O4; molecular weight 420.85 g/mol.
- Used as a carboxylic acid intermediate for NHS-ester formation and other coupling reactions.
- Supplied as a white to off-white solid suitable for synthetic workflows.
- High reported purity of 95.3% for reliable reaction performance.
- Available in small milligram quantities for research use.
- Store sealed, away from moisture; in solvent store at -80°C (6 months) or -20°C (1 month).
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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DSK BIOPHARMA INC CYANOACETYLENE 5G
Cyanoacetylene 5Gcas# 1070-71-9mdl# MFCD01696133
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 288-32-4 | Imidazole | Chem-Impex | MFCD00005183 | 68.079 | C3H4N2 | 99.000 | c1c[nH]cn1 | 25kg | 526509717
Imidazole | Chem-Impex | 288-32-4 | MFCD00005183 | 68.079 | C3H4N2 | 99.000 | c1c[nH]cn1 | 25kg | 526509717
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 288-32-4 | Imidazole | Chem-Impex | MFCD00005183 | 68.079 | C3H4N2 | 99.000 | c1c[nH]cn1 | 1kg | 272385127
Imidazole | Chem-Impex | 288-32-4 | MFCD00005183 | 68.079 | C3H4N2 | 99.000 | c1c[nH]cn1 | 1kg | 272385127
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Matrix Scientific 2-ETHYLPYRROLE, 98%-1G
2-Ethylpyrrole, 98%, 1G, MOLWT: 95.15, CAS# 1551-06-0, MFCD00060477
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 254-79-5 | 1,5-Naphthyridine | Ambeed | MFCD00039727 | 130.15 | C8H6N2 | 98 | c1cnc2cccnc2c1 | 1g | 491168597
Ambeed | Ethyl 2-bromovalerate | 25g | 628567075 | A1483653 | 615-83-8 | MFCD00000159 | 209.083 | C7H13BrO2
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Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC RK-582 | 2171388-28-4 | 98.1% | 510.60 | 100 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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RK-582 is an orally bioavailable tankyrase inhibitor and antitumor agent, demonstrating potent inhibition of human tankyrase-1 (IC50 36.1 nM) and tankyrase-2 (IC50 39.2 nM). Its efficacy in APC-mutated colorectal cancer cells correlates with active β-catenin levels, making it valuable for colorectal cancer research.
- Potent tankyrase inhibitor.
- Functions as an antitumor agent and orally bioavailable growth inhibitor.
- Effective in APC-mutated colorectal cancer cells.
- Demonstrates high selectivity over PARP1, PARP2, and PARP10.
- Inhibits Wnt/β-catenin signaling.
- Inhibits growth of COLO-320DM human colorectal cancer cells (GI50 = 0.035 μM).
- Induces AXIN2 accumulation and reduces active β-catenin levels.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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