Indoles and derivatives
![10,15-Dihydro-5H-diindolo[3,2-a:3',2'-c]carbazole 98.0+%, TCI America™](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-109005-10-9.jpg-250.jpg)
10,15-Dihydro-5H-diindolo[3,2-a:3',2'-c]carbazole 98.0+%, TCI America™
CAS: 109005-10-9 Molecular Formula: C24H15N3 Molecular Weight (g/mol): 345.405 MDL Number: MFCD21609440 InChI Key: IQRFZFGTHZJRFV-UHFFFAOYSA-N Synonym: 10,15-Dihydro-5H-5,10,15-triazadiindeno[1,2-a:1′,2′-c]fluorene PubChem CID: 13707158 SMILES: C1=CC=C2C(=C1)C3=C(N2)C4=C(C5=C3NC6=CC=CC=C65)NC7=CC=CC=C74
Medchemexpress LLC BPR1M97 | 2059904-66-2 | 99.4% | 10 MG
BPR1M97 is a dual-acting mu opioid receptor (MOP) and nociceptin-orphanin FQ peptide (NOP) receptor agonist. It exhibits high potency, penetrates the blood-brain barrier, and produces potent antinociceptive effects.
- Dual-acting mu opioid receptor (MOP) agonist
- Nociceptin-orphanin FQ peptide (NOP) receptor agonist
- High potency
- Penetrates blood-brain barrier
- Produces potent antinociceptive effects
- For research use only
Medchemexpress LLC Dibromocarbazole | 136630-39-2 | 99.9% | 325.00 | 10 G
2,7-Dibromocarbazole is a biochemical reagent intended for life science research, functioning as a biological material or organic compound. This product is for laboratory use only, suitable for the manufacture of substances by qualified scientists in equipped facilities, and is not for sale to patients.
- Functions as a biological material or organic compound
- Suitable for life science research
- Intended for laboratory and research use only
- Identified for the manufacture of substances
- Stable under recommended storage conditions
- Targeted for biochemical assay reagents
- Soluble in DMSO at 100 mg/mL
- Appearance is a white to off-white solid
- Product complies with given specifications
- Not validated for medical applications
Medchemexpress LLC PGAM1-IN-2 | 2438637-66-0 | 98.0% | 10 MG
PGAM1-IN-2 is a phosphoglycerate mutase 1 (PGAM1) inhibitor with an IC50 of 2.1 μM. This compound inhibits H1299 proliferation with an IC50 of 33.8±6.1 μM.
- Potent phosphoglycerate mutase 1 inhibitor
- Inhibits H1299 proliferation
- Suitable for research applications
Medchemexpress LLC Parp-2-in-1 | 2115698-83-2 | 99.6% | 465.40 g·mol⁻¹ | C21H19F4N5O3 | 10 MG
PARP-2-IN-1 is a potent, selective inhibitor of poly(ADP-ribose) polymerase 2 (PARP-2) used in research on DNA damage response and programmed cell death. It exhibits an IC50 of 11.5 nM against PARP-2 and is supplied as a high-purity small-molecule reagent for laboratory studies.
- Potent and selective PARP-2 inhibition (IC50 11.5 nM).
- High purity suitable for research (>99.5% by HPLC).
- Well-characterized molecular properties (C21H19F4N5O3, 465.40 g·mol⁻¹).
- Available in small mg-scale quantities for laboratory research.
- Suitable for biochemical and cell-based assays studying DNA repair and apoptosis.
- Provided with product datasheet and analytical data.
Medchemexpress LLC 6-Chloro-2-fluoro-9H-purine | 1651-29-2 | 172.55 | 10 G
6-Chloro-2-fluoro-9H-purine is a biochemical reagent that can be used as a biological material or organic compound for various life science related research applications.
- Utilized as a biochemical reagent
- Can be used as a biological material or organic compound
- Solid appearance, light yellow to yellow in color
- Molecular formula: C5H2ClFN4
- Purity: 99.2%
- Molecular weight: 172.55
- CAS number: 1651-29-2
- Melting/freezing point: 162-163°C
- Boiling point/range: 553.2°C at 760 mmHg
- Relative density: 1.98 g/cm³
- Recommended storage at -20°C, sealed, away from moisture
- When in solvent, store at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Sirt-in-2 | 1431411-66-3 | 98.1% | 383.49 | C15H21N5O3S2 | 10 MG
Sirt-in-2 is a potent, low-nanomolar inhibitor of sirtuin deacetylases SIRT1, SIRT2, and SIRT3 intended for laboratory research. The compound is provided as a high-purity solid (typical purity 98.1%) in a milligram pack for preparing stock solutions; it is for research use only and not for human use.
- Inhibits SIRT1, SIRT2, and SIRT3 with IC50s of 4 nM, 1 nM, and 7 nM, respectively.
- High purity suitable for biochemical and cell-based assays (≈98.1%).
- Molecular formula C15H21N5O3S2 and molecular weight 383.49.
- Supplied as a milligram-scale solid (e.g., 10 mg) for preparing stock solutions.
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC GSK2292767 | 1254036-66-2 | MFCD22572737 | 98.9% | 512.58 | C24H28N6O5S | 10 MG
GSK2292767 is a potent, selective PI3Kδ inhibitor supplied for preclinical research use. It is provided as a solid (light yellow to yellow) with reported purity of 98.89% and CAS 1254036-66-2, packaged in small-mass quantities suitable for in vitro and exploratory in vivo studies. Store as powder refrigerated or frozen according to supplier recommendations.
- Potent and selective PI3Kδ inhibition (pIC50 ~10.1).
- High reported purity for reliable experimental use.
- Available in small-mass quantities for screening and dosing studies.
- Solid form suitable for solution preparation and storage.
- Documented storage conditions for powder and stock solutions.
Medchemexpress LLC 3-Indolyl acetate | 608-08-2 | 99.3% | 175.18 | 10 G
3-Indolyl acetate is an ester derivative of indole that is ubiquitous in various plant tissues, especially in certain cruciferous vegetables such as broccoli and cabbage. It acts as an important signaling molecule in plants, regulating physiological processes such as growth and defense against pathogens. It also has potential applications in the pharmaceutical industry, as it has been shown to have antitumor and anti-inflammatory effects in some studies. As a biochemical reagent, it can be used as a biological material or organic compound for life science related research.
- Ester derivative of indole
- Found in various plant tissues
- Regulates plant growth and defense mechanisms
- Shows potential antitumor effects
- Shows potential anti-inflammatory effects
- Suitable for life science-related research
Medchemexpress LLC My-875 | 2974348-62-2 | MFCD34676541 | 99.6% | 387.43 | C21H25NO6 | 10 MG
MY-875 is a competitive microtubulin polymerization inhibitor that targets the colchicine binding site and activates the Hippo signaling pathway. It induces apoptosis, causes G2/M cell-cycle arrest, and exhibits dose-dependent antiproliferative activity in multiple cancer cell lines; reported tubulin polymerization IC50 is 0.92 μM. The compound is supplied as a high-purity solid with high solubility in DMSO and recommended storage to preserve stability.
- Competitive microtubulin polymerization inhibitor targeting colchicine binding sites.
- Activates Hippo pathway leading to YAP degradation.
- Induces apoptosis and G2/M cell-cycle arrest in cancer cells.
- Demonstrates potent antiproliferative activity (tubulin polymerization IC50 ~0.92 μM).
- High purity solid with high DMSO solubility for assay preparation.
- Stable under recommended storage conditions for experimental reproducibility.
Medchemexpress LLC Sid 26681509 | 958772-66-2 | 99.2% | 539.65 g/mol | C27H33N5O5S | 10 MG
A potent, reversible, competitive small-molecule inhibitor of human cathepsin L with reported in vitro and in vivo activity. The compound is a white to off-white solid (molecular weight 539.65 g/mol, CAS 958772-66-2) and is supplied in small quantities for research use.
- Potent cathepsin L inhibition (IC50 = 56 nM; potency increases to IC50 = 1.0 nM after 4 h preincubation).
- High reported purity (99.16%).
- Available as small solid quantities and as a 10 mM solution in DMSO for screening.
- Demonstrated in vitro activity against Plasmodium falciparum and Leishmania major.
- Suitable for biochemical assays and in vivo models of inflammation and sepsis.
![Medchemexpress LLC 1-[5-(thiophen-2-ylmethoxy)-1H-indol-3-yl]propan-2-amine;hydrochloride | 160521-72-2 | MFCD01321066 | 99.8% | 322.85 | C16H19ClN2OS | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000211646.png-250.jpg)
Medchemexpress LLC 1-[5-(thiophen-2-ylmethoxy)-1H-indol-3-yl]propan-2-amine;hydrochloride | 160521-72-2 | MFCD01321066 | 99.8% | 322.85 | C16H19ClN2OS | 10 MG
BW-723C86 is a research-grade selective 5-HT2B receptor agonist provided in solid and DMSO solution formats for in vitro and in vivo pharmacology studies. It exhibits high purity and has documented solubility and storage recommendations to support experimental reproducibility. Use only as directed for research purposes and follow safety and handling instructions from the supplier's safety documentation.
- Selective 5-HT2B receptor agonist.
- High purity suitable for pharmacological assays.
- Available as solid or ready-to-use DMSO solution.
- High solubility in DMSO (≈100 mg/mL) for easy formulation.
- In vivo formulation protocols provided to aid dosing.
- Storage recommendations provided to preserve stability.
- Intended for research use only.
Medchemexpress LLC (S)-2-(2-(1H-indol-3-yl)acetamido)-3-phenylpropanoic acid | 57105-50-7 | 97.2% | 322.36 | 10 G
(S)-2-(2-(1H-Indol-3-yl)acetamido)-3-phenylpropanoic acid is a phenylalanine derivative intended for research use. Amino acids and amino acid derivatives, including this product, are recognized as beneficial ergogenic dietary substances that have been commercially utilized as supplements.
- Influences anabolic hormones
- Supplies fuel during exercise
- Improves mental performance during stress-related tasks
- Prevents exercise-induced muscle damage
Medchemexpress LLC 3,4,5-Trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-2-thiazolyl)-benzamide | 461000-66-8 | MFCD03115431 | 98.9% | 428.50 | C22H24N2O5S | 10 MG
Eact is a small-molecule activator of the calcium-activated chloride channel TMEM16A (ANO1) that also directly activates TRPV1 channels in sensory nociceptors, producing itch, acute nociception, and thermal hypersensitivity. It is supplied as a purified white to off-white solid for research use with characterized physicochemical and solubility properties.
- Selective activator of TMEM16A and TRPV1 channels.
- High purity solid (≈98.9%) suitable for in vitro and in vivo studies.
- Soluble in DMSO (50 mg/mL) and formulatable for in vivo use (≥2.5 mg/mL in 10% DMSO/90% corn oil).
- Useful for electrophysiology and behavioral assays probing ion channel function.
- Stable under recommended storage conditions for long-term use.
Medchemexpress LLC N-Boc-indole-2-boronic acid | 213318-44-6 | MFCD02093045 | 99.95% | C13H16BNO4 | 10 G
(1-(tert-Butoxycarbonyl)-1H-indol-2-yl)boronic acid, also known as N-Boc-indole-2-boronic acid, is a high-purity biochemical reagent with a molecular formula of C13H16BNO4 and a molecular weight of 261.08. It is commonly used as a biological material or organic compound in various life science-related research applications.
- Biochemical reagent for life science research
- Organic compound suitable for various applications
- High purity of 99.95%
- Stable under recommended storage conditions: -20°C, sealed, away from moisture